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6-Ethyl-5-iodopyriMidine-2,4-diaMine

Product Name
6-Ethyl-5-iodopyriMidine-2,4-diaMine
CAS No.
514854-13-8
Chemical Name
6-Ethyl-5-iodopyriMidine-2,4-diaMine
Synonyms
6-Ethyl-5-iodopyriMidine-2,4-diaMine;"2,4-Diamino-6-ethyl-5-iodopyrimidine";2,4-Pyrimidinediamine, 6-ethyl-5-iodo-;6-Ethyl-5-iodopyrimidine-2,4-diamine 97%;2,4-Diamino-6-ethyl-5-iodopyrimidine, 2,4-Diamino-6-ethyl-5-iodo-1,3-diazine
CBNumber
CB72685901
Molecular Formula
C6H9IN4
Formula Weight
264.07
MOL File
514854-13-8.mol
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6-Ethyl-5-iodopyriMidine-2,4-diaMine Property

Boiling point:
431.3±55.0 °C(Predicted)
Density 
1.951±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
6.26±0.10(Predicted)
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

AK Scientific
Product number
7175AB
Product name
6-Ethyl-5-iodopyrimidine-2,4-diamine
Packaging
100mg
Price
$145
Updated
2021/12/16
Apolloscientific
Product number
OR52066
Product name
6-Ethyl-5-iodopyrimidine-2,4-diamine
Purity
97%
Packaging
250mg
Price
$154
Updated
2021/12/16
SynQuest Laboratories
Product number
3730-H-X4
Product name
6-Ethyl-5-iodopyrimidine-2,4-diamine
Packaging
250mg
Price
$170
Updated
2021/12/16
Apolloscientific
Product number
OR52066
Product name
6-Ethyl-5-iodopyrimidine-2,4-diamine
Purity
97%
Packaging
1g
Price
$383
Updated
2021/12/16
SynQuest Laboratories
Product number
3730-H-X4
Product name
6-Ethyl-5-iodopyrimidine-2,4-diamine
Packaging
1g
Price
$423
Updated
2021/12/16
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6-Ethyl-5-iodopyriMidine-2,4-diaMine Chemical Properties,Usage,Production

Synthesis

514854-12-7

514854-13-8

General procedure for the synthesis of 6-ethyl-5-iodopyrimidine-2,4-diamine from 2,4-diamino-6-ethylpyrimidine: a suspension of 2,4-diamino-6-ethylpyrimidine (0.8750 g, 5.00 mmol) and iodine monochloride (0.40 mL, 7.50 mmol) was stirred for 2 h at room temperature in methanol (15 mL). Upon completion of the reaction, water (5 mL) was added and the pH was adjusted with 10% NaOH aqueous solution to 7. Subsequently, the reaction mixture was extracted with ethyl acetate (15 mL each time) three times, and the organic phases were combined and dried with anhydrous MgSO4. Finally, the solvent was removed by evaporation to afford the light brown solid product 6-ethyl-5-iodopyrimidine-2,4-diamine (1.1355 g, 86% yield).

References

[1] Patent: WO2017/52479, 2017, A1. Location in patent: Page/Page column 10
[2] Journal of Chemical Research - Part S, 2002, # 10, p. 482 - 484
[3] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 15, p. 3947 - 3963

6-Ethyl-5-iodopyriMidine-2,4-diaMine Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Ethyl-5-iodopyriMidine-2,4-diaMine Suppliers

Hunan HuaTeng Pharmaceutical Co., Ltd.,
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514854-13-8, 6-Ethyl-5-iodopyriMidine-2,4-diaMineRelated Search:


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  • 6-Ethyl-5-iodopyriMidine-2,4-diaMine
  • 2,4-Diamino-6-ethyl-5-iodopyrimidine, 2,4-Diamino-6-ethyl-5-iodo-1,3-diazine
  • 2,4-Pyrimidinediamine, 6-ethyl-5-iodo-
  • "2,4-Diamino-6-ethyl-5-iodopyrimidine"
  • 514854-13-8