6-Ethyl-5-iodopyriMidine-2,4-diaMine
- Product Name
- 6-Ethyl-5-iodopyriMidine-2,4-diaMine
- CAS No.
- 514854-13-8
- Chemical Name
- 6-Ethyl-5-iodopyriMidine-2,4-diaMine
- Synonyms
- 6-Ethyl-5-iodopyriMidine-2,4-diaMine;"2,4-Diamino-6-ethyl-5-iodopyrimidine";2,4-Pyrimidinediamine, 6-ethyl-5-iodo-;6-Ethyl-5-iodopyrimidine-2,4-diamine 97%;2,4-Diamino-6-ethyl-5-iodopyrimidine, 2,4-Diamino-6-ethyl-5-iodo-1,3-diazine
- CBNumber
- CB72685901
- Molecular Formula
- C6H9IN4
- Formula Weight
- 264.07
- MOL File
- 514854-13-8.mol
6-Ethyl-5-iodopyriMidine-2,4-diaMine Property
- Boiling point:
- 431.3±55.0 °C(Predicted)
- Density
- 1.951±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 6.26±0.10(Predicted)
Safety
- HS Code
- 2933599590
N-Bromosuccinimide Price
- Product number
- 7175AB
- Product name
- 6-Ethyl-5-iodopyrimidine-2,4-diamine
- Packaging
- 100mg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- OR52066
- Product name
- 6-Ethyl-5-iodopyrimidine-2,4-diamine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $154
- Updated
- 2021/12/16
- Product number
- 3730-H-X4
- Product name
- 6-Ethyl-5-iodopyrimidine-2,4-diamine
- Packaging
- 250mg
- Price
- $170
- Updated
- 2021/12/16
- Product number
- OR52066
- Product name
- 6-Ethyl-5-iodopyrimidine-2,4-diamine
- Purity
- 97%
- Packaging
- 1g
- Price
- $383
- Updated
- 2021/12/16
- Product number
- 3730-H-X4
- Product name
- 6-Ethyl-5-iodopyrimidine-2,4-diamine
- Packaging
- 1g
- Price
- $423
- Updated
- 2021/12/16
6-Ethyl-5-iodopyriMidine-2,4-diaMine Chemical Properties,Usage,Production
Synthesis
514854-12-7
514854-13-8
General procedure for the synthesis of 6-ethyl-5-iodopyrimidine-2,4-diamine from 2,4-diamino-6-ethylpyrimidine: a suspension of 2,4-diamino-6-ethylpyrimidine (0.8750 g, 5.00 mmol) and iodine monochloride (0.40 mL, 7.50 mmol) was stirred for 2 h at room temperature in methanol (15 mL). Upon completion of the reaction, water (5 mL) was added and the pH was adjusted with 10% NaOH aqueous solution to 7. Subsequently, the reaction mixture was extracted with ethyl acetate (15 mL each time) three times, and the organic phases were combined and dried with anhydrous MgSO4. Finally, the solvent was removed by evaporation to afford the light brown solid product 6-ethyl-5-iodopyrimidine-2,4-diamine (1.1355 g, 86% yield).
References
[1] Patent: WO2017/52479, 2017, A1. Location in patent: Page/Page column 10
[2] Journal of Chemical Research - Part S, 2002, # 10, p. 482 - 484
[3] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 15, p. 3947 - 3963
6-Ethyl-5-iodopyriMidine-2,4-diaMine Preparation Products And Raw materials
Raw materials
Preparation Products
6-Ethyl-5-iodopyriMidine-2,4-diaMine Suppliers
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
- Tel
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- Fax
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- info@synthonix.com
- Country
- United States
- ProdList
- 6872
- Advantage
- 58
- Tel
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- info@synquestlabs.com
- Country
- United States
- ProdList
- 6871
- Advantage
- 62