ChemicalBook > CAS DataBase List > (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate

(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate

Product Name
(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
CAS No.
874638-94-5
Chemical Name
(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
Synonyms
Sofosbuvir imp-6;Sofosbuvir Impurity X;2'-epi-Sofosbuvir Desphosphate;Sofosbuvir Dibenzoyl Amino Impurity;(2R,3R,4R,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((be...;(2R,3R,4R,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate;Benzamide, N-[1-[(2R)-3,5-di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-α-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-;N-[1-[(2R)-3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-alpha-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide;Sofosbuvir impurity 21/(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
CBNumber
CB72705027
Molecular Formula
C31H26FN3O7
Formula Weight
571.56
MOL File
874638-94-5.mol
More
Less

(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate Property

Melting point:
174-175 °C(Solv: dichloromethane (75-09-2); hexane (110-54-3))
Density 
1.34±0.1 g/cm3(Predicted)
pka
8.51±0.20(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
S675625
Product name
2’-epi-SofosbuvirDesphosphate
Packaging
10mg
Price
$1980
Updated
2021/12/16
ChemScene
Product number
CS-M2820
Product name
(2R,3R,4R,5S)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-ylbenzoate
Packaging
100mg
Price
$360
Updated
2021/12/16
ChemScene
Product number
CS-M2820
Product name
(2R,3R,4R,5S)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-ylbenzoate
Packaging
250mg
Price
$600
Updated
2021/12/16
ChemScene
Product number
CS-M2820
Product name
(2R,3R,4R,5S)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-ylbenzoate
Packaging
1g
Price
$1200
Updated
2021/12/16
Chemenu
Product number
CM156928
Product name
(2R,3R,4R,5S)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-ylbenzoate
Purity
95%
Packaging
1g
Price
$1122
Updated
2021/12/16
More
Less

(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate Chemical Properties,Usage,Production

Uses

2’-epi-Sofosbuvir Desphosphate is possible metabolite of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C.

(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate Suppliers

China 51 India 1 United States 5 Global 57
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Acesys Pharmatech
Tel
18860950986
Email
tangmanman@zenjipharma.com
Country
China
ProdList
1733
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18333
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50
Nanjing Chempioneer Pharmaceutical Co., Ltd.
Tel
18068075658
Fax
-
Email
sales@chempioneer.com
Country
China
ProdList
1811
Advantage
58
Shanghai XingTai Pharmaceutical Technology co., LTD
Tel
15801747407
Fax
+86 021 51388225
Email
sales01@suntechpharma.com
Country
China
ProdList
123
Advantage
58
Hubei Yangxin Medical Technology Co., Ltd.
Tel
15374522761
Fax
QQ:2853117752
Email
3003392093@yongstandards.com
Country
China
ProdList
10000
Advantage
55
Jiaxing Deyi Chemical Co., Ltd.
Tel
86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8593
Advantage
58
PI & PI BIOTECH INC.
Tel
+86-13602409664 +86-17788709170
Fax
020-81716319
Email
Sales@pipitech.com
Country
China
ProdList
2649
Advantage
58
Abydos Scientific
Tel
025-84767922 18936879710
Email
sales@abydoscientific.com
Country
China
ProdList
1002
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
ANHUI WITOP BIOTECH CO., LTD
Tel
+8615255079626
Email
eric@witopchemical.com
Country
China
ProdList
23541
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
Hangzhou Huarong Pharm Co., Ltd.
Tel
571-86758373 +8613588754946
Fax
0086-571-81131109
Email
sales@huarongpharm.com
Country
CHINA
ProdList
3148
Advantage
58
AFINE CHEMICALS LIMITED
Tel
+86-0571-85134551
Fax
008657185134895
Email
sales@afinechem.com
Country
China
ProdList
15109
Advantage
58
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
020-36607679 19925672674
Fax
QQ 3008233717
Email
3008233746@qq.com
Country
China
ProdList
9883
Advantage
12
Jinan blalong chemical co. LTD
Tel
2710913286@.com
Email
1513643261@qq.com
Country
China
ProdList
14246
Advantage
58
Shanghai Payne Pharmaceutical Technology Co.Ltd
Tel
021-58123769 17721400256
Email
info@paynepharm.com
Country
China
ProdList
1285
Advantage
58
Shanghai Payne Pharmaceutical Technology Co.Ltd
Tel
021-58123769 18678586262
Email
info@paynepharm.com
Country
China
ProdList
1354
Advantage
58
Shenzhen ruikai de biotechnology co., ltd.
Tel
0755-61348847 17820674378
Fax
0755-21016893
Email
2682116078@qq.com
Country
China
ProdList
7843
Advantage
58
Nanjing Becas pharmatech Ltd.
Tel
13912903754
Email
info@becaspharma.com
Country
China
ProdList
2763
Advantage
58
Wuxi Minglu Medicine technology Co.,Ltd.
Tel
0510-88726693
Fax
0510-88726693
Email
3204601684@qq.com
Country
China
ProdList
2215
Advantage
58
Wuxi Helen Biotechnology Co., Ltd.,
Tel
0510-85629785 18013409632
Fax
0510-85625359
Email
sales@reading-chemicals.com
Country
China
ProdList
14081
Advantage
58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8860
Advantage
58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD
Tel
0755-0755-83725350 13380397412
Fax
0755-28094224
Email
3001280422@qq.com
Country
China
ProdList
10001
Advantage
58
Guangzhou Juntang Technology Co., Ltd
Tel
020-36607679 13502246435
Email
sales@dmstandards.com
Country
China
ProdList
10945
Advantage
58
Foshan Treasure Biotechnology Co., Ltd
Tel
0757-85921206 18520245316
Email
2329783215@qq.com
Country
China
ProdList
12661
Advantage
58
Changzhou Xianglong Pharmaceutical Technology Co., LTD
Tel
18661161657
Email
yaoxiangqiu2021@163.com
Country
China
ProdList
9968
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
QUALITY CONTROL SOLUTIONS LTD.
Tel
+86-0755-66853366 +86-13670046396
Email
export03@qcsrm.com
Country
China
ProdList
24342
Advantage
58
Molcoo Chemicals Inc.
Tel
18576690171
Email
3001025734@qq.com
Country
China
ProdList
8880
Advantage
58
Huaihua Yuanyanda Biotechnology Co., Ltd
Tel
18711085600
Email
1652923704@qq.com
Country
China
ProdList
4628
Advantage
58
Scinova Biotech(Guangzhou) Co., Ltd.
Tel
13268215580
Email
scinova_sales@163.com
Country
China
ProdList
7025
Advantage
58
Hubei Wanye Zhongcheng Chemical Reagent Co., Ltd.
Tel
18671296875
Email
1205035102@qq.com
Country
China
ProdList
4302
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
Shanghai Zerui Biotechnology Co., Ltd.
Tel
021-54580889 18321124657
Fax
021-54580889
Email
731997554@qq.com
Country
China
ProdList
10608
Advantage
58
https://hanhongsci.com/
Tel
021-54306202 18917919676
Email
info@hanhongsci.com
Country
China
ProdList
29995
Advantage
58
Shenzhen Qingtian Biotechnology Co, Ltd.
Tel
18823167005 18162969855
Email
744288988@qq.com
Country
China
ProdList
2629
Advantage
58
Shenzhen Xingyue Biotechnology Co., Ltd
Tel
18124513697; 18124513697
Fax
18822823697
Email
jjj18822823697@163.com
Country
China
ProdList
1377
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
hanfangpharma@126.com; 18616537568
Email
hanfangpharma@126.com
Country
China
ProdList
29965
Advantage
58
Hubei Moco Chemical Co., Ltd.
Tel
18627753421; 18627756402
Fax
QQ：3001051413
Email
3001051413@qq.com
Country
China
ProdList
20319
Advantage
58
Minglong (Xianning) Pharmaceutical Co., LTD
Tel
186-7296-9259 18771307593
Email
3919539926@qq.com
Country
China
ProdList
4258
Advantage
58
Huaihua Yuanyanda Biotechnology Co., Ltd
Tel
18229999901
Email
18711085600@163.com
Country
China
ProdList
4590
Advantage
58
Shanghai Titan Scientific Co.,Ltd
Tel
16621234537
Email
chenyj@titansci.com
Country
China
ProdList
10000
Advantage
58
Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-010-52878169 15801002657
Email
sales@bjcomparison.com
Country
China
ProdList
5096
Advantage
58
Hangzhou Yiyun Guoke Biotechnology Co., Ltd.
Tel
17717523804
Email
1211221625@qq.com
Country
China
ProdList
8568
Advantage
58
Moxin Chemicals
Tel
+86-17320513646 +8617320513646
Email
anna@molcoo.com
Country
China
ProdList
10000
Advantage
58
China National Standard Pharmaceutical Corporation Limited
Tel
+8615391658522
Email
overseasales@yongstandards.com
Country
China
ProdList
11922
Advantage
58

874638-94-5, (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoateRelated Search:

Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI) PSI-7977-13C-d3 SofosBuvir Impurity 52 PSI-7976 SofosBuvir impurity 44 SofosBuvir impurity 45 PSI 7411 N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester SofosBuvir Impurity 39 (R)-isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate Sofosbuvir (2R,3R,4R,5R)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-chloro-4-Methyltetrahydrofuran-3-yl benzoate Sofosbuvir impurity D L-Alanine, N-[(S)-hydroxyphenoxyphosphinyl]-, 1-Methylethyl ester, (P→3'),(P'→5')-diester with (2'R)-2'-deoxy-2'-fluoro-2'-Methyluridine 1-((2S,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione SofosBuvir Impurity 14 SofosBuvir Impurity 50 Sofosbuvir Impurity 67

  • N-[1-[(2R)-3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-alpha-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide
  • 2'-epi-Sofosbuvir Desphosphate
  • Sofosbuvir Impurity X
  • Sofosbuvir impurity 21/(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
  • Sofosbuvir imp-6
  • Benzamide, N-[1-[(2R)-3,5-di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-α-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-
  • Sofosbuvir Dibenzoyl Amino Impurity
  • (2R,3R,4R,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((be...
  • (2R,3R,4R,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate
  • 874638-94-5