(R)-AMbrisentan

Product Name: (R)-AMbrisentan
CAS No.: 1007358-76-0
Chemical Name: (R)-AMbrisentan
Synonyms: (R)-AMbrisentan;Ambrisentan Impurity 5;(2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid;Benzenepropanoic acid, α-[(4,6-dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenyl-, (αR)-
CBNumber: CB72706312
Molecular Formula: C22H22N2O4
Formula Weight: 378.43
MOL File: 1007358-76-0.mol

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(R)-AMbrisentan Property

Melting point:: >161°C (dec.)
Boiling point:: 551.1±60.0 °C(Predicted)
Density: 1.228±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Sparingly, Heated, Sonicated)
form: Solid
pka: 0.97±0.10(Predicted)
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A575873
Product name: (R)-Ambrisentan
Packaging: 10mg
Price: $450
Updated: 2021/12/16

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(R)-AMbrisentan Chemical Properties,Usage,Production

Uses

(R)-Ambrisentan is the R-isomer impurity of Ambrisentan (A575860), which is a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.

(R)-AMbrisentan Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-AMbrisentan Suppliers

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1007358-76-0, (R)-AMbrisentanRelated Search:

(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester 2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3,3-diphenyl-2-propenoic Acid MATFPFPXUXCLHI-UHFFFAOYSA-N Benzenepropanoic acid,a-hydroxy-b-methoxy-b-phenyl-,(aS)- rac-Ambrisentan-d5 4,6-Dimethyl-2-hydroxypyrimidine Ambrisentan Ambrisentan pyrimidine Ester Impurity Ambrisentan Hydroxy Acid Impurity (R-isomer) (S)-4-HydroxyMethyl AMbrisentan 4-Hydroxymethyl ambrisentan acyl beta-glucuronide Ambrisentan N-Oxide Ambrisentan Acyl Glucuronide (Mixture of Diastereomers) 4-Hydroxy Methyl Ambrisentan-D3

(R)-AMbrisentan

(2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid

Ambrisentan Impurity 5

Benzenepropanoic acid, α-[(4,6-dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenyl-, (αR)-

1007358-76-0