2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid

Product Name: 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid
CAS No.: 1211443-58-1
Chemical Name: 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid
Synonyms: Ribociclib Intermediate 1;2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d];2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxy...;2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid;7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 2-chloro-7-cyclopentyl-
CBNumber: CB72729571
Molecular Formula: C12H12ClN3O2
Formula Weight: 265.7
MOL File: 1211443-58-1.mol

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2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid Property

Density: 1.61±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 3.63±0.30(Predicted)
Appearance: White to light yellow Solid
InChI: InChI=1S/C12H12ClN3O2/c13-12-14-6-7-5-9(11(17)18)16(10(7)15-12)8-3-1-2-4-8/h5-6,8H,1-4H2,(H,17,18)
InChIKey: LXCZVGKSFJMLRO-UHFFFAOYSA-N
SMILES: C1(Cl)=NC=C2C=C(C(O)=O)N(C3CCCC3)C2=N1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: C587358
Product name: 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylicAcid
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: C587358
Product name: 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylicAcid
Packaging: 500mg
Price: $155
Updated: 2021/12/16

Matrix Scientific

Product number: 153521
Product name: 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid
Purity: 95%
Packaging: 1g
Price: $79
Updated: 2021/12/16

AK Scientific

Product number: 9954DN
Product name: 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylicacid
Packaging: 100mg
Price: $91
Updated: 2021/12/16

Matrix Scientific

Product number: 153521
Product name: 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid
Purity: 95%
Packaging: 5g
Price: $277
Updated: 2021/12/16

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2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid Chemical Properties,Usage,Production

Synthesis

1211443-55-8

1211443-58-1

2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde (2.69 g, 11 mmol) was used as starting material and dissolved in DMF. Subsequently, Oxone (7.2 g, 12 mmol) was added to this solution and the reaction was stirred at room temperature for 6 hours. After completion of the reaction, water was added to the reaction mixture to precipitate the target product. The yellow solid, 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid (2.69 g, 85% yield) was collected by filtration. Mass spectrum (ESI) m/z 266 [M + H]+.

References

[1] Patent: WO2010/20675, 2010, A1. Location in patent: Page/Page column 91

2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid Suppliers

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View Lastest Price from 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid manufacturers

Career Henan Chemical Co

Product: 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid 1211443-58-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98-100%
Supply Ability: 100KG
Release date: 2018-08-20

1211443-58-1, 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acidRelated Search:

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2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid

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1211443-58-1