ChemicalBook > CAS DataBase List > phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

Appearance

Product Name: phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
CAS No.: 379270-35-6
Chemical Name: phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Synonyms: Monophenylester;TAF Impurity 3;GS7340 impurity1;GS7340 intermediate 1;Tenofovir Impurity 30;Tenofovir alafenamide-4;Tenofovir Alafenamide acid;Tenofovir Related Compound 2;Tenofovir Alafenamide Impurity 28;Tenofovir Alafenamide Impurity 18
CBNumber: CB72729612
Molecular Formula: C15H18N5O4P
Formula Weight: 363.31
MOL File: 379270-35-6.mol

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phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Property

Melting point:: 237-239°C
Boiling point:: 610.1±65.0 °C(Predicted)
Density: 1.53±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated)
pka: 2.09±0.10(Predicted)
form: Solid
color: White to Off-White
InChI: InChI=1S/C15H18N5O4P/c1-11(7-20-9-19-13-14(16)17-8-18-15(13)20)23-10-25(21,22)24-12-5-3-2-4-6-12/h2-6,8-9,11H,7,10H2,1H3,(H,21,22)(H2,16,17,18)/t11-/m1/s1
InChIKey: ITAMCOCNZJPJDF-LLVKDONJSA-N
SMILES: C(P(=O)(O)OC1=CC=CC=C1)O[C@H](C)CN1C2C(N=C1)=C(N)N=CN=2

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A628898
Product name: [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester
Packaging: 1g
Price: $65
Updated: 2021/12/16

Ambeed

Product number: A670413
Product name: Phenylhydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Purity: 97%
Packaging: 250mg
Price: $40
Updated: 2021/12/16

Ambeed

Product number: A670413
Product name: Phenylhydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Purity: 97%
Packaging: 1g
Price: $84
Updated: 2021/12/16

Chemenu

Product number: CM138836
Product name: phenylhydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Purity: 95+%
Packaging: 5g
Price: $421
Updated: 2021/12/16

Alichem

Product number: 379270356
Product name: Phenylhydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Packaging: 5g
Price: $590.94
Updated: 2021/12/16

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phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Chemical Properties,Usage,Production

Appearance

White powder

Uses

[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.

Application

[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate manufacturers

Zison Pharmaceutical (Shandong) Co., Ltd.

Product: Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate 379270-35-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98% by HPLC
Supply Ability: 100kg/month
Release date: 2023-01-05

Shaanxi Dideu New Materials Co. Ltd

Product: phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 379270-35-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-05

Shanghai UCHEM Inc.

Product: Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate 379270-35-6
Price: US $80.00-416.00/g
Min. Order: 25g
Purity: 0.97
Supply Ability: 25kg
Release date: 2023-12-20

379270-35-6, phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonateRelated Search:

6N-HydroxyMethyl Tenofovir Disoproxil Tenofovir Related Compound 14 D-Alanine Isopropyl Ester HCl Tenofovir Alafenamide PMPA Impurity Tenofovir disoproxil Tenofovir isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Alafenamide Impurity 6 Tenofovir Related Compound 5 Tenofovir Alafenamide Impurity 30 Tenofovir Related Compound 4 diisopropyl 2,2'-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(azanediyl))(2S,2'S)-dipropionate compound with methane (1:1) Tenofovir Related Compound 6 isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy) phosphoryl)-D-alaninate isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Related Compound 1 isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Alafenamide

[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester

Tenofovir Related Compound 2

phenyl ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

GS7340 impurity1

GS7340 intermediate 1

phenylydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) phosphonate

phenyl hydrogen (R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

Phenyl hydrogen ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate

Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monophenylester

Tenofovir alafenamide-4

[2-(6-Amino-purin-9- yl)-1-methyl-ethoxy methyl]-phosphonic acid monophenyl ester

The intermediate of Tenofovir Alafenamide

Tenofovir alafenamide Intermediate

Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monophenyl ester (9CI)

Tenofovir Impurity 30

Tenofovir alafenamide Intermediate 1

Monophenylester

Tenofovir Alafenamide Impurity 28

TAF Impurity 3

Tenofovir Monophenyl Ester Impurity

Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methyleth...

(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-phenoxy-phosphinic acid

9-[(R)-2- (phenylphosphonomethoxy) propyl]adenine (PPMPA)

Tenofovir Alafenamide Fumarate N-3

Tenofovir Alafenamide acid

(S)-propyl 2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate

Tenofovir Alafenamide Impurity 18

phenyl hydrogen ({[[](2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate

379270-35-6

C15H18N5O4P

Intermediate

379270-35-6