1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]-
- Product Name
- 1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]-
- CAS No.
- 1334179-85-9
- Chemical Name
- 1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]-
- Synonyms
- BTTAA;inhibit,Inhibitor,BTTAA;(4-{[Bis-(1-tert-butyl-1H-[1,2,3]triazol-4-ylmethyl)-amino]-methyl}-[1,2,3]triazol-1-yl)-acetic acid;2-(4-((Bis(2,2-dimethyl-1-(1H-1,2,3-triazol-4-yl)propyl)amino)methyl)-1H-1,2,3-triazol-1-yl)aceticacid;2-(4-((bis((1-(tert-butyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid;1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]-;(4-((Bis((1-(2-methyl-2-propyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid;{4-[(Bis{[1-(2-methyl-2-propanyl)-1H-1,2,3-triazol-4-yl]methyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetic acid;(4-{[Bis-(1-tert-butyl-1H-[1,2,3]triazol-4-ylmethyl)-amino]-methyl}-[1,2,3]triazol-1-yl)-acetic acid (other name: BTTAA)
- CBNumber
- CB72730768
- Molecular Formula
- C19H30N10O2
- Formula Weight
- 430.51
- MOL File
- 1334179-85-9.mol
1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]- Property
- Boiling point:
- 620.7±65.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO, DMF, MeOH
- pka
- 3.33±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- InChI
- InChI=1S/C19H30N10O2/c1-18(2,3)28-11-15(21-24-28)8-26(7-14-10-27(23-20-14)13-17(30)31)9-16-12-29(25-22-16)19(4,5)6/h10-12H,7-9,13H2,1-6H3,(H,30,31)
- InChIKey
- MGQYHUDOWOGSQI-UHFFFAOYSA-N
- SMILES
- N1(CC(O)=O)C=C(CN(CC2=CN(C(C)(C)C)N=N2)CC2=CN(C(C)(C)C)N=N2)N=N1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H242Heating may cause a fire
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P234Keep only in original container.
P235Keep cool.
P240Ground/bond container and receiving equipment.
P370+P378In case of fire: Use … for extinction.
P403Store in a well-ventilated place.
N-Bromosuccinimide Price
- Product number
- 906328
- Product name
- BTTAA
- Purity
- ≥95%
- Packaging
- 100mg
- Price
- $255
- Updated
- 2024/03/01
- Product number
- 906328
- Product name
- BTTAA
- Purity
- ≥95%
- Packaging
- 500mg
- Price
- $545.4
- Updated
- 2024/03/01
- Product number
- orb611468
- Product name
- BTTAA
- Packaging
- 5mg
- Price
- $569.5
- Updated
- 2021/12/16
- Product number
- 35127
- Product name
- BTTAA,95%(HPLC)
- Purity
- 95%(HPLC)
- Packaging
- 250MG
- Price
- $582.4
- Updated
- 2021/12/16
- Product number
- 35127
- Product name
- BTTAA,95%(HPLC)
- Purity
- 95%(HPLC)
- Packaging
- 100MG
- Price
- $291.2
- Updated
- 2021/12/16
1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]- Chemical Properties,Usage,Production
Description
BTTP is a newest generation, accelerating ligand for CuAAC that provides much greater rate enhancement compared to previous generation ligands (e.g. THPTA or TBTA). More importantly, it minimizes perturbations to the physiological state of the cells or organisms probed and allows for effective bioconjugation with suppressed cell cytotoxicity by further lowering copper loading in the catalyst formulation. Nature Communications. 5: 4981(2014) Chem Asian J., 6(10), 2796-802(2011)
Uses
BTTAA is a next-generation, water-soluble ligand for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that dramatically accelerates reaction rates and suppresses cell cytotoxicity. The biocompatibility and fast kinetics of BTTAA are advancements from water-insoluble TBTA and are desirable for bio conjugation in diverse chemical biology experiments.
1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]- Suppliers
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View Lastest Price from 1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]- manufacturers
- Product
- BTTAA 1334179-85-9
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >95.00%
- Supply Ability
- 100mg
- Release date
- 2024-03-22