MICROCYSTIN YR
- Product Name
- MICROCYSTIN YR
- CAS No.
- 101064-48-6
- Chemical Name
- MICROCYSTIN YR
- Synonyms
- MICROCYSTIN YR;Cyanoginosin-yr;Cyanoginosin yr;Microcystin YR (9CI);MICROCYSTIN-YR SOLUTION;Pentoxifylline Impurity 29;Cyanoginosin la, 3-tyrosyl-5-arginine-;Cyanoginosin la, 3-L-tyrosyl-5-L-arginine;microcystin yr from microcystis aeruginosa;Cyanoginosin la, 3-L-tyrosine-5-L-arginine
- CBNumber
- CB7273847
- Molecular Formula
- C52H72N10O13
- Formula Weight
- 1045.19
- MOL File
- 101064-48-6.mol
MICROCYSTIN YR Property
- Density
- 1.33±0.1 g/cm3(Predicted)
- Flash point:
- 11 °C
- storage temp.
- −20°C
- solubility
- methanol: 2 mg/mL (further dilute to 10% (v/v) methanol)
- pka
- 3.02±0.70(Predicted)
- form
- white powder
- EPA Substance Registry System
- Cyclo[2,3-didehydro-N-methylalanyl-D-alanyl-L-tyrosyl-(3S)-3-methyl-D-.beta.-aspartyl-L-arginyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-.gamma.-glutamyl] (101064-48-6)
Safety
- Hazard Codes
- T+,T,F
- Risk Statements
- 26/27/28-36/37/38-43-39/23/24/25-23/24/25-11
- Safety Statements
- 26-36/37/39-45-36/37-16-7
- RIDADR
- UN 2811 6.1/PG 1
- WGK Germany
- 3
- RTECS
- 000000030272
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H300Fatal if swallowed
H301Toxic if swalloed
H310Fatal in contact with skin
H311Toxic in contact with skin
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H330Fatal if inhaled
H331Toxic if inhaled
H335May cause respiratory irritation
H370Causes damage to organs
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P350IF ON SKIN: Gently wash with plenty of soap and water.
P311Call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 33576
- Product name
- Microcystin-YR solution
- Purity
- 10μg/mL in methanol, analytical standard
- Packaging
- 1ml
- Price
- $564
- Updated
- 2024/03/01
- Product number
- TOX0000326
- Product name
- MICROCYSTIN-YR
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.51
- Updated
- 2021/12/16
MICROCYSTIN YR Chemical Properties,Usage,Production
Uses
Microcystin YR from Microcystis aeruginosa has been used to assess cytotoxicity in neutrophils using DNA fragmentation and cell viability assays and as a reference standard in the quantification of microcystin from water samples.
General Description
Microcystin is a potent cyanotoxin produced by the bloom of Microcystis aeruginosa. It is harmful to aquatic animals. It is a heptapeptide and exists as multiple variant forms. pCO2 and nitrogen levels modulate the toxic variants levels. It elicits damage to the liver and other organs.
Biochem/physiol Actions
Microcystin YR inhibits protein phosphatase type 2A and protein phosphatase type 1. Toxicity to undifferentiated cells was seen by inhibition of neutral red uptake, >80% at 100 μM, after 48 h.