ChemicalBook > CAS DataBase List > 1-TRIMETHYLSILYLMETHANOL

1-TRIMETHYLSILYLMETHANOL

Product Name
1-TRIMETHYLSILYLMETHANOL
CAS No.
3219-63-4
Chemical Name
1-TRIMETHYLSILYLMETHANOL
Synonyms
DK264;NSC 96777;rimethylsilylmethanol;(trimethylsilyl)-methano;1-TRIMETHYLSILYLMETHANOL;(TRIMETHYLSILYL)METHANOL;Methanol, (trimethylsilyl)-;TRIMETHYLHYDROXYMETHYLSILANE;Methanol,1-(trimethylsilyl)-;1-TRIMETHYLSILYLMETHANOL, 98+%
CBNumber
CB7284458
Molecular Formula
C4H12OSi
Formula Weight
104.22
MOL File
3219-63-4.mol
More
Less

1-TRIMETHYLSILYLMETHANOL Property

Melting point:
<0°C
Boiling point:
120-122 °C754 mm Hg(lit.)
Density 
0.826 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.419(lit.)
Flash point:
88 °F
storage temp. 
2-8°C
form 
clear liquid
pka
15.92±0.10(Predicted)
Specific Gravity
0.827
color 
Colorless to Almost colorless
Water Solubility 
Fully miscible in water.
Hydrolytic Sensitivity
1: no significant reaction with aqueous systems
BRN 
1731486
CAS DataBase Reference
3219-63-4(CAS DataBase Reference)
EPA Substance Registry System
Methanol, (trimethylsilyl)- (3219-63-4)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
UN 1987 3/PG 3
WGK Germany 
3
RTECS 
PC4100000
TSCA 
Yes
HS Code 
2931.90.9010
HazardClass 
3
PackingGroup 
III
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
T1250
Product name
Trimethylsilylmethanol
Purity
>97.0%(GC)
Packaging
5mL
Price
$113
Updated
2024/03/01
TCI Chemical
Product number
T1250
Product name
Trimethylsilylmethanol
Purity
>97.0%(GC)
Packaging
25mL
Price
$389
Updated
2024/03/01
Alfa Aesar
Product number
L04251
Product name
1-Trimethylsilylmethanol, 95%
Packaging
1g
Price
$37.65
Updated
2024/03/01
Alfa Aesar
Product number
L04251
Product name
1-Trimethylsilylmethanol, 95%
Packaging
5g
Price
$156.65
Updated
2024/03/01
Usbiological
Product number
291767
Product name
Trimethylsilylmethanol
Packaging
2g
Price
$313
Updated
2021/12/16
More
Less

1-TRIMETHYLSILYLMETHANOL Chemical Properties,Usage,Production

Uses

1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent.

Purification Methods

If the NMR indicates impurities (should have only two signals), then dissolve it in Et2O, shake this with aqueous 5N NaOH, M H2SO4, saturated aqueous NaCl, dry (MgSO4) and distil it using an efficient column at atmospheric pressure. The 3,5-dinitrobenzoate has m 70-70.5o (from 95% EtOH). [Huang & Wang Acta Chem Sin 23 291 1957, cf. Chem Abstr 52 19911 1958, Speier et al. J Am Chem Soc 81 1844 1959 and Speier et al. J Am Chem Soc 70 1117 1948, Beilstein 4 III 1844, 4 IV 2876.]

1-TRIMETHYLSILYLMETHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-TRIMETHYLSILYLMETHANOL Suppliers

Belgium 2 China 85 Germany 4 India 3 Italy 1 Japan 2 Singapore 1 Switzerland 1 The Netherlands 2 United Kingdom 7 United States 29 Global 137
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
ChemFuture PharmaTech (Jiangsu) Ltd
Tel
5108538618
Fax
86 510 85386988-8017
Email
suger.wang@chemfuture.com
Country
China
ProdList
822
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Shanghai Hanhong Scientific Co.,Ltd.
Tel
Country
China
ProdList
42982
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5700
Advantage
66
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
Guangzhou Egg Biotechnology Co., Ltd.
Tel
86-20-28069315 28069316
Fax
86-20-28069316
Email
eggbio@163.com
Country
China
ProdList
20
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9352
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai Gileader Advanced Material Technology Co.,Ltd
Tel
021-69980372 18516111942
Email
823898732@qq.com
Country
China
ProdList
1336
Advantage
56
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9352
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Shanghai Enchem Industry Co., Ltd.
Tel
15021317485
Fax
021-58109752
Country
China
ProdList
1403
Advantage
58
Shanghai Zhuang Ming New Material Technology Co., Ltd.
Tel
17312398916 051386936896 15216715905
Fax
051386936896
Email
sales@zhuangming.net
Country
China
ProdList
1271
Advantage
58
Shanghai Synchem Pharma Co., ltd
Tel
021-61984905-1 18016477331
Email
synchempharma@aliyun.com
Country
China
ProdList
6456
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
5881
Advantage
65
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13349
Advantage
58
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19806
Advantage
60
Aikon International Limited
Tel
025-58851090 13611564524
Fax
(6)02557626880
Email
lwan@aikonchem.com
Country
China
ProdList
15952
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17997
Advantage
58
Suzhou Siso new material Co.,Ltd.
Tel
0512-65402974 18550909935;
Fax
0512-67544899
Email
siso03@126.com
Country
China
ProdList
1892
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
Country
China
ProdList
20532
Advantage
60
Shanghai neon biological technology co., LTD
Tel
021-54252912-8903
Email
leona.xin@forneeds.cn
Country
China
ProdList
4762
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-63315541 13323832564
Fax
QQ:3001332135
Email
3001332135@qq.com
Country
China
ProdList
9998
Advantage
58
Suzhou Adelaide Chemical Technology Co., Ltd.
Tel
15995785122
Email
3003020078@qq.com
Country
China
ProdList
1198
Advantage
58
Hunan chemfish Scientific co.,ltd
Tel
+8619313119731 15528049369
Email
sales@chemfish.com
Country
China
ProdList
4911
Advantage
58
Anhui Silicon Innovation Materials Technology Co., Ltd.
Tel
15155150338 17201714774
Email
3317543774@qq.com
Country
China
ProdList
1085
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
0551-65418671
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34572
Advantage
58
CD Chemical Group Limited
Tel
+8615986615575
Fax
0086-13651442114
Email
info@codchem.com
Country
China
ProdList
20356
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
CHINA
ProdList
52867
Advantage
58
WinWin Chemical CO., Limited
Tel
+86-0577-64498589 +8615325081899
Fax
0086-577-56994596
Email
sales@win-winchemical.com
Country
China
ProdList
14151
Advantage
58
SIMAGCHEM CORP
Tel
+86-13806087780
Email
sale@simagchem.com
Country
China
ProdList
17367
Advantage
58
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
chemwill_asia@126.com
Country
CHINA
ProdList
23931
Advantage
58
Shenyang Maud Pharmaceutical Technology Co., Ltd.
Tel
024-23982345
Email
1020788318@qq.com
Country
China
ProdList
2254
Advantage
58
Wuhan Rongcan Biotechnology Co., Ltd
Tel
18327024450
Fax
183-27024450
Email
2130026275@qq.com
Country
China
ProdList
4590
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 15093356674;
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29826
Advantage
58
Hubei kefule Material Technology Co., Ltd
Tel
027-84459282 13720265353
Email
zhou@cfmats.com
Country
China
ProdList
881
Advantage
58
Hubei Co-Formula Material Tech Co., Ltd.
Tel
+86-27-84459282
Fax
+86-27-84459282
Email
sales@cfmats.com
Country
CHINA
ProdList
882
Advantage
58
Shanghai Qiming New Material Co. LTD
Tel
021-36010885 13661599081
Fax
021-66167180
Email
sale@qmsilicon.com
Country
China
ProdList
1506
Advantage
58
Zhengzhou Alpha Chemical Co. LTD
Tel
0371-0371-53732842 13383863444
Fax
QQ：3002612166
Email
3002612166@qq.com
Country
China
ProdList
10014
Advantage
58
Henan Vocas Biotechnology Co., Ltd
Tel
0185-37671377 18537671377
Fax
QQ3487632979
Email
vocas@foxmail.com
Country
China
ProdList
5011
Advantage
58
Mainchem Co., Ltd.
Tel
--
Fax
--
Email
sarah@mainchem.com
Country
China
ProdList
6572
Advantage
58
More
Less

View Lastest Price from 1-TRIMETHYLSILYLMETHANOL manufacturers

Career Henan Chemical Co
Product
1-TRIMETHYLSILYLMETHANOL 3219-63-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
KG/T
Release date
2019-12-17

3219-63-4, 1-TRIMETHYLSILYLMETHANOLRelated Search:

3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE TRIMETHYLSILYL DIETHYLPHOSPHONOACETATE (TRIMETHYLSILYL)CYCLOPENTADIENE, MIXTURE OF ISOMERS TRIMETHYLSILYL PROPIONATE TRIMETHYLSILYL TRIFLUOROACETATE 1-TRIMETHYLSILYLMETHANOL (TRIMETHYLSILYL)METHYL TRIFLUOROMETHANESULFONATE 1-(TRIMETHYLSILYL)ETHANOL, 98 (METHOXYMETHYL)TRIMETHYLSILANE (1-ETHOXYVINYL)-TRIMETHYLSILANE ACRYLOXYMETHYLTRIMETHYLSILANE (PHENYLDIMETHYLSILYL)METHYL METHACRYLATE (1-HYDROXYALLYL)TRIMETHYLSILANE 1-TRIETHYLSILYL-4-(TRIETHLYLSILYLOXY)-1-BUTYNE METHACRYLOXYMETHYLTRIMETHYLSILANE (2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine (1-METHOXYVINYL)TRIMETHYLSILANE TRIMETHYLSILYLMETHYL ACETATE

  • (hydroxymethyl)trimethyl-silan
  • (trimethylsilyl)-methano
  • Methanol, (trimethylsilyl)-
  • Silane, (hydroxymethyl)trimethyl-
  • TRIMETHYLHYDROXYMETHYLSILANE
  • (TRIMETHYLSILYL)METHANOL
  • 1-TRIMETHYLSILYLMETHANOL
  • (HYDROXYMETHYL)TRIMETHYLSILANE
  • 1-TRIMETHYLSILYLMETHANOL, 98+%
  • (Trimethylsilyl)methanol,(Hydroxymethyl)trimethylsilane
  • NSC 96777
  • Methanol,1-(trimethylsilyl)-
  • rimethylsilylmethanol
  • DK264
  • 3219-63-4
  • C4H12OSi
  • CH33SiCH2OH
  • Alcohols
  • Building Blocks
  • C2 to C6
  • Organic Building Blocks
  • Oxygen Compounds
  • Silicon Compounds (for Synthesis)
  • Si (Classes of Silicon Compounds)
  • Si-(C)4 Compounds
  • Si (Classes of Silicon Compounds)
  • Si-(C)4 Compounds
  • Silicon Compounds (for Synthesis)
  • Synthetic Organic Chemistry