ChemicalBook > CAS DataBase List > AKOS B019512

AKOS B019512

Product Name
AKOS B019512
CAS No.
5775-82-6
Chemical Name
AKOS B019512
Synonyms
AKOS B019512;ART-CHEM-BB B019512;TIMTEC-BB SBB005613;4-Bromo-1,3-dimethylpyrazole;4-Bromo-1,3-dimethyl-1H-pyrazole;1H-Pyrazole, 4-bromo-1,3-dimethyl-;4-bromo-1,3-dimethyl-1H-pyrazole(SALTDATA: FREE)
CBNumber
CB7287101
Molecular Formula
C5H7BrN2
Formula Weight
175.03
MOL File
Mol file
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AKOS B019512 Property

Boiling point:
100 °C(Press: 30 Torr)
Density 
1.487 g/mL at 25 °C
refractive index 
1.5214 (estimate)
Flash point:
103 °C
storage temp. 
2-8°C
form 
liquid
pka
0.68±0.10(Predicted)
Appearance
Colorless to light yellow Liquid
InChI
InChI=1S/C5H7BrN2/c1-4-5(6)3-8(2)7-4/h3H,1-2H3
InChIKey
UESOBPUTZLYSGI-UHFFFAOYSA-N
SMILES
N1(C)C=C(Br)C(C)=N1
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-39
HazardClass 
IRRITANT
HS Code 
29331990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B691718
Product name
4-Bromo-1,3-dimethylpyrazole
Packaging
500mg
Price
$65
Updated
2021/12/16
Apolloscientific
Product number
OR910091
Product name
4-Bromo-1,3-dimethylpyrazole
Purity
95%
Packaging
1g
Price
$70
Updated
2021/12/16
AK Scientific
Product number
V6734
Product name
4-Bromo-1,3-dimethylpyrazole
Packaging
250mg
Price
$73
Updated
2021/12/16
Matrix Scientific
Product number
030917
Product name
4-Bromo-1,3-dimethyl-1H-pyrazole
Purity
95+%
Packaging
5g
Price
$78
Updated
2021/12/16
Matrix Scientific
Product number
030917
Product name
4-Bromo-1,3-dimethyl-1H-pyrazole
Purity
95+%
Packaging
1g
Price
$23
Updated
2021/12/16
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AKOS B019512 Chemical Properties,Usage,Production

Chemical Properties

White solid

Synthesis

694-48-4

5775-82-6

General procedure for the synthesis of 4-bromo-1,3-dimethyl-1H-pyrazole from 1,3-dimethyl-1H-pyrazole: Bromine (2.0 mL, 40.80 mmol) was added slowly and dropwise to a solution of 1,3-dimethyl-1H-pyrazole (3.92 g, 40.80 mmol) in acetic acid (10 mL) at room temperature. The reaction mixture was heated to 70 °C and maintained for 1 hour. Upon completion of the reaction, it was cooled to room temperature and concentrated under vacuum to give the crude product. The pH of the crude product was adjusted with saturated sodium carbonate solution to 7~8. Subsequently, extraction was carried out with ethyl acetate (50 mL x 3), the organic phases were combined and dried over anhydrous sodium sulfate. After filtration, the filtrate was concentrated under vacuum to give the residue. The residue was purified by column chromatography (eluent: ethyl acetate/petroleum ether = 1/6 to 1/4) to afford the target compound 4-bromo-1,3-dimethyl-1H-pyrazole (3.30 g, yield: 46%) as an oil. The product was detected by ESI-MS and showed (M + H)+ peak located at 175.1. 1H NMR (400 MHz, CDCl3) data were as follows: δ 7.30 (s, 1H), 3.83 (s, 3H), 2.23 (s, 3H).

References

[1] J. Gen. Chem. USSR (Engl. Transl.), 1980, vol. 50, # 9, p. 1714 - 1716
[2] Zhurnal Obshchei Khimii, 1980, vol. 50, # 9, p. 2116 - 2119
[3] Patent: WO2015/89327, 2015, A1. Location in patent: Paragraph 0296
[4] Chemische Berichte, 1926, vol. 59, p. 606,1296

AKOS B019512 Preparation Products And Raw materials

Raw materials

Preparation Products

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AKOS B019512 Suppliers

China 76 Germany 1 India 1 Russia 1 Switzerland 1 United Kingdom 2 United States 9 Global 91
Accela ChemBio Inc.
Tel
+1(858) 699-3322
Fax
+1(858) 876-1948
Email
marketing@accelachem.com
Country
United States
ProdList
6024
Advantage
65
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
TimTec Corporation
Tel
--
Fax
--
Email
info@timtec.net
Country
United States
ProdList
6891
Advantage
68

5775-82-6, AKOS B019512Related Search:

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  • AKOS B019512
  • ART-CHEM-BB B019512
  • 4-Bromo-1,3-dimethylpyrazole
  • TIMTEC-BB SBB005613
  • 4-Bromo-1,3-dimethyl-1H-pyrazole
  • 4-bromo-1,3-dimethyl-1H-pyrazole(SALTDATA: FREE)
  • 1H-Pyrazole, 4-bromo-1,3-dimethyl-
  • 5775-82-6