2-AMINO-4-BROMOBENZALDEHYDE
Application- Product Name
- 2-AMINO-4-BROMOBENZALDEHYDE
- CAS No.
- 59278-65-8
- Chemical Name
- 2-AMINO-4-BROMOBENZALDEHYDE
- Synonyms
- Ambroxol Impurity 60;2-Amino-4-bromobenzaL;4-BroMo-2-aMinobenzaldehyde;2-AMINO-4-BROMOBENZALDEHYDE;Benzaldehyde, 2-amino-4-bromo-;2-AMINO-4-BROMOBENZALDEHYDE ISO 9001：2015 REACH
- CBNumber
- CB7294688
- Molecular Formula
- C7H6BrNO
- Formula Weight
- 200.03
- MOL File
- 59278-65-8.mol
2-AMINO-4-BROMOBENZALDEHYDE Property
- Melting point:
- 85 °C
- Boiling point:
- 317.1±32.0 °C(Predicted)
- Density
- 1.672±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- pka
- -0.72±0.10(Predicted)
- Appearance
- Off-white to yellow Solid
- InChI
- InChI=1S/C7H6BrNO/c8-6-2-1-5(4-10)7(9)3-6/h1-4H,9H2
- InChIKey
- ZZVUOSVSPAPBEJ-UHFFFAOYSA-N
- SMILES
- C(=O)C1=CC=C(Br)C=C1N
Safety
- HS Code
- 2922390090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A594835
- Product name
- 2-Amino-4-bromobenzaldehyde
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- W7224
- Product name
- 2-Amino-4-bromobenzaldehyde
- Packaging
- 1g
- Price
- $107
- Updated
- 2021/12/16
- Product number
- OR51844
- Product name
- 2-Amino-4-bromobenzaldehyde
- Packaging
- 1g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- FA139324
- Product name
- 2-Amino-4-bromobenzaldehyde
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 4656-9-44
- Product name
- 2-Amino-4-bromobenzaldehyde
- Packaging
- 1g
- Price
- $154
- Updated
- 2021/12/16
2-AMINO-4-BROMOBENZALDEHYDE Chemical Properties,Usage,Production
Application
2-Amino-4-bromobenzaldehyde is an organic synthesis intermediate and a pharmaceutical intermediate that can be used in laboratory research and development processes as well as in chemical and pharmaceutical synthesis.
Synthesis
5551-12-2
59278-65-8
Step 3. Synthesis of 2-amino-4-bromobenzaldehyde: Iron powder was added to 0.2 M of 4-bromo-2-nitrobenzaldehyde in a mixed solvent system of acetic acid and ethanol (v/v 1:1) under argon protection. The reaction mixture was stirred at room temperature for 1.5 h. The completion of the reaction was confirmed by LCMS monitoring. The insoluble solids were removed by filtration and the filtrate was concentrated under vacuum. The residue was diluted with ethyl acetate, washed sequentially with saturated sodium bicarbonate solution and brine, and the organic phase was dried over anhydrous sodium sulfate and concentrated. The crude product was purified by Biotage system using hexane solution of 15% ethyl acetate as eluent to afford the target compound 2-amino-4-bromobenzaldehyde in 38% yield.ES/MS m/z 200/202 (MH+).
References
[1] Tetrahedron Letters, 2016, vol. 57, # 45, p. 5003 - 5008
[2] Patent: WO2016/86200, 2016, A1. Location in patent: Page/Page column 219
[3] Patent: WO2007/117607, 2007, A2. Location in patent: Page/Page column 333-334
[4] Chemische Berichte, 1909, vol. 42, p. 3697
[5] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 7, p. 2462 - 2467
2-AMINO-4-BROMOBENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-4-BROMOBENZALDEHYDE manufacturers
- Product
- 2-AMINO-4-BROMOBENZALDEHYDE 59278-65-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-26
- Product
- 2-AMINO-4-BROMOBENZALDEHYDE 59278-65-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2019-12-30