N-Succinimidyl-N-methylcarbamate

Product Name: N-Succinimidyl-N-methylcarbamate
CAS No.: 18342-66-0
Chemical Name: N-Succinimidyl-N-methylcarbamate
Synonyms: SuO-NM;methyl isocyanate substitute;N-Succinimidyl-N-methylcarbame;N-Succinimidyl Methylcarbamate;N-Succinimidyl-N-methylcarbama;N-SUCCINIMDYL-N-METHYLCARBAMATE;N-SUCCINIMIDYL-N-METHYLCARBAMATE;2,5-dioxopyrrolidin-1-yl MethylcarbaMate;Methylcarbamic Acid N-Succinimidyl Ester;N-Succinimidyl N-methylcarbamate >=97.0% (N)
CBNumber: CB7301533
Molecular Formula: C6H8N2O4
Formula Weight: 172.14
MOL File: 18342-66-0.mol

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N-Succinimidyl-N-methylcarbamate Property

Melting point:: 148-153 °C
Density: 1.41±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Dichloromethane (Slightly), DMSO (Slightly)
pka: 11.00±0.46(Predicted)
form: Solid
color: White to Off-White
Water Solubility: Slightly soluble in water.
Sensitive: Moisture Sensitive
BRN: 1531863
CAS DataBase Reference: 18342-66-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 10-21
HS Code: 2928.00.5000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 66181
Product name: N-Succinimidyl N-methylcarbamate
Purity: ≥97.0% (N)
Packaging: 5g
Price: $312
Updated: 2024/03/01

Sigma-Aldrich

Product number: 66181
Product name: N-Succinimidyl N-methylcarbamate
Purity: ≥97.0% (N)
Packaging: 25g
Price: $638
Updated: 2023/06/20

TCI Chemical

Product number: U0108
Product name: N-Succinimidyl Methylcarbamate
Purity: >98.0%(N)
Packaging: 1g
Price: $25
Updated: 2024/03/01

TCI Chemical

Product number: U0108
Product name: N-Succinimidyl Methylcarbamate
Purity: >98.0%(N)
Packaging: 5g
Price: $69
Updated: 2024/03/01

Alfa Aesar

Product number: H63566
Product name: N-Succinimidyl N-methylcarbamate, 97%
Packaging: 1g
Price: $36
Updated: 2023/06/20

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N-Succinimidyl-N-methylcarbamate Chemical Properties,Usage,Production

Uses

N-Succinimidyl N-Methylcarbamate is used as a reagent in the synthesis of Argifin, a natural product chitinase inhibitor with chemotherapeutic potential. N-Succinimidyl N-Methylcarbamate is also used as a reagent in the preparation of 5-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide (A616300); a metabolite of Temozolomide (T017775) which is an imidazotetrazine alkylating agent and antineoplastic.

Definition

ChEBI: N-succinimidyl N-methylcarbamate is a member of the class of pyrrolidinones that is N-hydroxysuccinimide in which the hydroxyl hydrogen is replaced by a methylcarbamoyl group. It has a role as an apoptosis inducer. It is a carbamate ester, a dicarboximide, a pyrrolidinone and a N-hydroxysuccinimide ester. It is functionally related to a succinimide.

N-Succinimidyl-N-methylcarbamate Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Succinimidyl-N-methylcarbamate Suppliers

China 107 Germany 2 India 3 Japan 1 South Korea 1 Switzerland 1 United States 20 Global 135

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View Lastest Price from N-Succinimidyl-N-methylcarbamate manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: N-Succinimidyl-N-methylcarbamate 18342-66-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: N-Succinimidyl-N-Methylcarbamate 18342-66-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: N-Succinimidyl-N-Methylcarbamate 18342-66-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

18342-66-0, N-Succinimidyl-N-methylcarbamateRelated Search:

POLYURETHANE Methyl anthranilate Urethane Dithiooxamide 4-Aminobenzoic acid 6-Aminoquinolyl-N-hydroxysuccinimidylcarbamate Anthranilic acid TERT-BUTYL N-SUCCINIMIDYL N,N'-TRIMETHYLENEDICARBAMATE TERT-BUTYL N-SUCCINIMIDYL N,N'-(1,4-PHENYLENE)DICARBAMATE TERT-BUTYL-N-SUCCINIMIDYL N N'-ETHYLENE- N-SucciniMidoxycarbonyl-β-alanine N-SucciniMidyl Ester TERT-BUTYL N-SUCCINIMIDYL N,N'-HEXAMETHYLENEDICARBAMATE CARBAMIC ACID, (2-CHLOROETHYL)NITROSO-, 2,5-DIOXO-1-PYRROLIDINYL ESTER TERT-BUTYL N-SUCCINIMIDYL N,N'-TETRAMETHYLENEDICARBAMATE N-Succinimidyl-N-methylcarbamate

2,5-PYRROLIDINEDIONE, 1-[[(METHYLAMINO)CARBONYL]OXY]-

N-SUCCINIMDYL-N-METHYLCARBAMATE

N-SUCCINIMIDYL-N-METHYLCARBAMATE

N-Succinimidyl-N-methylcarbama

methyl isocyanate substitute

Methyl isocyanate substitute, MIC substitute

2,5-dioxopyrrolidin-1-yl MethylcarbaMate

SuO-NM

N-Succinimidyl Methylcarbamate

N-Succinimidyl-N-methylcarbame

N-Succinimidyl N-methylcarbamate >=97.0% (N)

Methylcarbamic Acid N-Succinimidyl Ester

1-[[(Methylamino)carbonyl]oxy]-2,5-pyrrolidinedione

1-[(Methylcarbamoyl)oxy]-2,5-pyrrolidinedione

18342-66-0

8342-66-0

C6H8N2O4

Synthetic Reagents

Coupling

Active Esters/Additives

Norbornene Derivatives

Medical Intermediates