ChemicalBook > CAS DataBase List > (SAR1,ILE4,8)-ANGIOTENSIN II

(SAR1,ILE4,8)-ANGIOTENSIN II

Product Name
(SAR1,ILE4,8)-ANGIOTENSIN II
CAS No.
185461-45-4
Chemical Name
(SAR1,ILE4,8)-ANGIOTENSIN II
Synonyms
Octapeptide (NMe) G-RVIIHPI;(SAR1,ILE4,8)-ANGIOTENSIN II;SAR-ARG-VAL-ILE-ILE-HIS-PRO-ILE;SAR-ARG-VAL-ILE-ILE-HIS-PRO-ILE-OH;REF DUPL: Sar-Arg-Val-Ile-Ile-His-Pro-Ile-OH;(Sar1,Ile4,8)-Angiotensin II、SII-Angiotensin II;(Sar 1,Ile4·8)-Angiotensin II trifluoroacetate salt;L-Isoleucine, N-methylglycyl-L-arginyl-L-valyl-L-isoleucyl-L-isoleucyl-L-histidyl-L-prolyl-;(Sar 1,Ile4·8)-Angiotensin II trifluoroacetate salt Sar-Arg-Val-Ile-Ile-His-Pro-Ile-OH trifluoroacetate salt
CBNumber
CB7302545
Molecular Formula
C43H75N13O9
Formula Weight
918.14
MOL File
185461-45-4.mol
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(SAR1,ILE4,8)-ANGIOTENSIN II Property

Density 
1.34±0.1 g/cm3(Predicted)
form 
Solid
pka
3.72±0.22(Predicted)
color 
White to off-white
Sequence
{Sar}-Arg-Val-Ile-Ile-His-Pro-Ile
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PEP0010287
Product name
(SAR1,ILE4,8)-ANGIOTENSIN-II
Purity
95.00%
Packaging
5MG
Price
$497.23
Updated
2021/12/16
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(SAR1,ILE4,8)-ANGIOTENSIN II Chemical Properties,Usage,Production

Uses

(Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β[1].

IC 50

Angiotensin II Type 1

References

[1] Sanni SJ, et al. [Sar1, Ile4, Ile8]-angiotensin II Potentiates Insulin Receptor Signalling and Glycogen Synthesis in Hepatocytes. Basic Clin Pharmacol Toxicol. 2018 May;122(5):460-469. DOI:10.1111/bcpt.12937

(SAR1,ILE4,8)-ANGIOTENSIN II Preparation Products And Raw materials

Raw materials

Preparation Products

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185461-45-4, (SAR1,ILE4,8)-ANGIOTENSIN IIRelated Search:


  • (SAR1,ILE4,8)-ANGIOTENSIN II
  • SAR-ARG-VAL-ILE-ILE-HIS-PRO-ILE-OH
  • SAR-ARG-VAL-ILE-ILE-HIS-PRO-ILE
  • REF DUPL: Sar-Arg-Val-Ile-Ile-His-Pro-Ile-OH
  • (Sar 1,Ile4·8)-Angiotensin II trifluoroacetate salt Sar-Arg-Val-Ile-Ile-His-Pro-Ile-OH trifluoroacetate salt
  • L-Isoleucine, N-methylglycyl-L-arginyl-L-valyl-L-isoleucyl-L-isoleucyl-L-histidyl-L-prolyl-
  • Octapeptide (NMe) G-RVIIHPI
  • (Sar 1,Ile4·8)-Angiotensin II trifluoroacetate salt
  • (Sar1,Ile4,8)-Angiotensin II、SII-Angiotensin II
  • 185461-45-4
  • C43H75N13O9