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ANGIOTENSIN II, HUMAN

Product Name
ANGIOTENSIN II, HUMAN
CAS No.
4474-91-3
Chemical Name
ANGIOTENSIN II, HUMAN
Synonyms
Ang II;DRVYIHPF;TY-10721;ANGIOTENSIN-2;H-DRVYIHPF-OH;ANGIOTENSIN II;angiotensin renin;ANTI-ANGIOTENSIN II;ile(5)-angiotensini;[ILE5]-ANGIOTENSIN 2
CBNumber
CB0338057
Molecular Formula
C50H71N13O12
Formula Weight
1046.18
MOL File
4474-91-3.mol
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ANGIOTENSIN II, HUMAN Property

Boiling point:
809.08°C (rough estimate)
Density 
1.1257 (rough estimate)
refractive index 
1.6700 (estimate)
RTECS 
BW2165000
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form 
Powder
pka
pK1: 10.37 (25°C)
color 
orange
Water Solubility 
Soluble in Water (25 mg/ml), and 5% Acetic Acid (1 mg/ml).
InChIKey
CZGUSIXMZVURDU-JZXHSEFVSA-N
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A9525
Product name
Angiotensin II human
Purity
≥93% (HPLC), powder
Packaging
1mg
Price
$31.6
Updated
2021/03/22
Sigma-Aldrich
Product number
05-23-0101
Product name
Angiotensin II, Human - CAS 4474-91-3 - Calbiochem
Purity
Plays an important role in the regulation of blood pressure.
Packaging
1 mg
Price
$43.38
Updated
2021/03/22
Sigma-Aldrich
Product number
05-23-0101
Product name
Angiotensin II, Human - CAS 4474-91-3 - Calbiochem
Purity
Plays an important role in the regulation of blood pressure.
Packaging
5 mg
Price
$54.76
Updated
2021/03/22
Sigma-Aldrich
Product number
A9525
Product name
Angiotensin II human
Purity
≥93% (HPLC), powder
Packaging
5x1mg
Price
$124
Updated
2021/03/22
Sigma-Aldrich
Product number
05-23-0101
Product name
Angiotensin II, Human - CAS 4474-91-3 - Calbiochem
Purity
Plays an important role in the regulation of blood pressure.
Packaging
25 mg
Price
$205
Updated
2021/03/22
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ANGIOTENSIN II, HUMAN Chemical Properties,Usage,Production

Description

It is known that tumor tissues including metastatic lymph nodes are composed of newly growing vessels which lack blood flow autoregulation and are influenced only secondarily by the responding somatic vessels. Human angiotensin II (AT II). a vasopressor, was introduced in Japan to improve the efficacy of systemic chemotherapy. In patients with various advanced cancers, i.v. infusion of AT II to achieve a mean blood pressure of 1.5 times of baseline (but not over 150 mm Hg) followed by a bolus injection of conventional cytotoxic agents increases blood flow 5-7 fold in tumor tissues and therefore, increases drug delivery to the target tissue resulting in enhanced chemotherapeutic effects. This induced-hypertension chemotherapy regimen can be performed safely with minimal side effects.

Originator

Toa Eiyo (Japan)

Uses

Cardiopulmonary resuscitation - not yet an approved application

Uses

A peptide involved in the regulation of blood pressure

Uses

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two distinct receptors, AT1 and AT2, each evoking distinct signaling pathways and physiological responses. The development of antagonists for specific angiotensin II receptor subtypes represents a valuable alternative to ACE inhibitors.

brand name

Delivert

ANGIOTENSIN II, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

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ANGIOTENSIN II, HUMAN Suppliers

Beijing NuoqiYa Biotechnology Co., Ltd.
Tel
4000-819-385 010-62329685 13718666987
Fax
010-62340519
Email
good@nuoqiya.com
Country
China
ProdList
1973
Advantage
55
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973132-
Email
3329726100@qq.com
Country
China
ProdList
22394
Advantage
68
MedChemexpress LLC
Tel
609-228-6898
Fax
609-228-5909
Email
sales@medchemexpress.com
Country
United States
ProdList
4787
Advantage
58
Nanjing chengqimei Biotechnology Co., Ltd
Email
2173594524@qq.com
Country
China
ProdList
2299
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-62971590-
Fax
010-62340519
Email
3462612863@qq.com
Country
China
ProdList
10589
Advantage
58
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15877
Advantage
69
GL Biochem (Shanghai) Ltd
Tel
21-61263452- ;21-61263452-
Fax
86-21-61263399
Email
ymbetter@glbiochem.com;ymbetter@glbiochem.com
Country
China
ProdList
9940
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202- ; ;
Email
jerry.ma@hanhonggroup.com;jerry.ma@hanhonggroup.com;jerry.ma@hanhonggroup.com
Country
China
ProdList
43255
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32358
Advantage
50
Chengdu XiYa Chemical Technology Co., Ltd.
Tel
;
Fax
0539-6365991
Email
sale@xiyashiji.com;3007716753@qq.com
Country
China
ProdList
10578
Advantage
57
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View Lastest Price from ANGIOTENSIN II, HUMAN manufacturers

career henan chemical co
Product
ANGIOTENSIN II, HUMAN 4474-91-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-12

4474-91-3, ANGIOTENSIN II, HUMANRelated Search:


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