ANGIOTENSIN III, HUMAN

Product Name: ANGIOTENSIN III, HUMAN
CAS No.: 13602-53-4
Chemical Name: ANGIOTENSIN III, HUMAN
Synonyms: RVYIHPF;ANGIOTENSIN III;ANGIOTENSIN III, HUMAN;Angiotensin III - 5 mg;angiotensin III, 5-Ile-;[DES-ASP1]-ANGIOTENSIN II;ARG-VAL-TYR-ILE-HIS-PRO-PHE;ANGIOTENSIN II HEPTAPEPTIDE;ANGIOTENSIN III ACETATE SALT;ANGIOTENSIN III (HUMAN, MOUSE)
CBNumber: CB1334627
Molecular Formula: C46H66N12O9
Formula Weight: 931.09
MOL File: 13602-53-4.mol

More

Less

ANGIOTENSIN III, HUMAN Property

Density: 1.39±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: H₂O: 1.0 mg/mL, clear, colorless
form: Lyophilized.
pka: 3.56±0.10(Predicted)
color: White to off-white
Sequence: Arg-Val-Tyr-Ile-His-Pro-Phe

More

Less

Safety

WGK Germany: 3
F: 10

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 21618
Product name: Angiotensin III (human, mouse)
Purity: ≥98%
Packaging: 5mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21618
Product name: Angiotensin III (human, mouse)
Purity: ≥98%
Packaging: 10mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 21618
Product name: Angiotensin III (human, mouse)
Purity: ≥98%
Packaging: 25mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 21618
Product name: Angiotensin III (human, mouse)
Purity: ≥98%
Packaging: 50mg
Price: $214
Updated: 2024/03/01

Biosynth Carbosynth

Product number: FA73194
Product name: Angiotensin III，human
Packaging: 10mg
Price: $289
Updated: 2021/12/16

More

Less

ANGIOTENSIN III, HUMAN Chemical Properties,Usage,Production

Description

Angiotensin III (Ang III) is a heptapeptide agonist at the angiotensin 1 (AT₁) and AT₂ receptors, with a 30-fold higher affinity for AT₂ compared with AT₁ in HEK293 cells. Ang III is the preferred agonist for renal AT₂ receptors, which are responsible for sodium excretion into the urine. Ang III induces the same level of aldosterone synthesis as Ang II but has lower vasoconstrictive activity in vivo. In the brain renin-angiotensin system, Ang III increases sympathetic nerve activity and vasopressin release and dampens the baroreflex leading to higher blood pressure.

Uses

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.

Definition

ChEBI: Angiotensin III is a peptide.

in vivo

Angiotensin III (7, 14 and 28 nmol/kg/min) increases urine sodium excretion (U_NaV), fractional excretion of sodium (FE_Na), and fractional excretion of lithium (FE_Li) in SD rat^[2]. In RAS (renin-angiotensin system), Angiotensin III increases sympathetic nerve activity and vasopressin release and decreases the baroreflex leading to higher blood pressure in rats^[3].

IC 50

AT2 Receptor

References

[1] Bosnyak S, et al. Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors. Clin Sci (Lond). 2011 Oct;121(7):297-303. DOI:10.1042/CS20110036
[2] Kemp BA, et al. Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors. Hypertension. 2012 Aug;60(2):387-95. DOI:10.1161/HYPERTENSIONAHA.112.191403
[3] Gao J, et al. A new strategy for treating hypertension by blocking the activity of the brain renin-angiotensin system with aminopeptidase A inhibitors. Clin Sci (Lond). 2014 Aug;127(3):135-48. DOI:10.1042/CS20130396

ANGIOTENSIN III, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

ANGIOTENSIN III, HUMAN Suppliers

China 88 Europe 1 Germany 2 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 2 United States 11 USA 1 Global 108

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

ApexBio Technology LLC

Tel: +1-832-696-8203
Fax: +1-832-641-3177
Email: info@apexbt.com
Country: United States
ProdList: 477
Advantage: 60

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29759
Advantage: 68

More

Less

View Lastest Price from ANGIOTENSIN III, HUMAN manufacturers

Career Henan Chemical Co

Product: ANGIOTENSIN III, HUMAN 13602-53-4
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-13

13602-53-4, ANGIOTENSIN III, HUMANRelated Search:

Angiotensin acetate ANGIOTENSIN II, HUMAN ABZ-GLY-4-NITRO-PHE-PRO-OH BZ-GLY-GLY-GLY-OH H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ACETATE SALT ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE Angiotensin ANGIOTENSIN III ANTIPEPTIDE (val4)-angiotensin iii acetate,[val4]-angiotensin iii acetate hydrate,(VAL4)-ANGIOTENSIN III [DES-ARG1]-ANGIOTENSIN III (ILE7)-ANGIOTENSIN III ACETATE HYDRATE ALA-ANGIOTENSIN III ANGIOTENSIN III (HUMAN, MOUSE),ANGIOTENSIN III, HUMAN,ANGIOTENSIN III (HUMAN, MOUSE),ANGIOTENSIN III, HUMAN,ANGIOTENSIN III angiotensin III, 1-desarginine- (DES-ASP1)-ANGIOTENSIN I (DES-ASP1,ILE8)-ANGIOTENSIN II Angiotensin III triacetate

ARG-VAL-TYR-ILE-HIS-PRO-PHE

ARG-VAL-TYR-ILE-HIS-PRO-PHE 2ACOH 4H2O

ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH CH3COOH 4H2O

H-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH

[DES-ASP1]-ANGIOTENSIN II

DES-ASP-1-ANGIOTENSIN II ACETATE SALT

ANGIOTENSIN III ACETATE SALT

ANGIOTENSIN III

ANGIOTENSIN III, HUMAN

ANGIOTENSIN III (HUMAN) 2ACOH 4H2O

Angiotensin III H-Arg-Val-Tyr-Ile-His-Pro-Phe-OH

ANGIOTENSIN III (HUMAN, MOUSE)

ANGIOTENSIN II HEPTAPEPTIDE

RVYIHPF

angiotensin III, 5-Ile-

Angiotensin III, human, mouse(3TFA)

2-8-Angiotensin II, 5-L-isoleucine-

Human angiotensin III/Angiotensin III(mouse)

ANGIOTENSIN III, HUMAN USP/EP/BP

Angiotensin Receptor,Inhibitor,Angiotensin III, human, mouse,inhibit

Angiotensin III, human, mouse（Acetate）

Angiotensin III - 5 mg

13602-53-4

Cardiovascular

Angiotensin

peptide