H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH
- Product Name
- H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH
- CAS No.
- 34273-12-6
- Chemical Name
- H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH
- Synonyms
- DRVYIHPFH;Angiotensin A;H2N-DRVYIHPFH-OH;ANGIOTENSIN (1-9);ANGIOTENSIN I (1-9);ANGIOTENSIN 1/2 (1-9);Des-Leu angiotensin I【human】;ALA-ARG-VAL-TYR-ILE-HIS-PRO-PHE;AngiotensinItrifluoroacetate sal;AngiotensinⅠtrifluoroacetate salt
- CBNumber
- CB6444417
- Molecular Formula
- C56H78N16O13
- Formula Weight
- 1183.32
- MOL File
- 34273-12-6.mol
H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH Property
- Density
- 1.46±0.1 g/cm3(Predicted)
- storage temp.
- -15°C
- solubility
- ≥118.3 mg/mL in DMSO; insoluble in EtOH; ≥51 mg/mL in H2O
- form
- solid
- pka
- 2.91±0.10(Predicted)
- Sequence
- Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His
Safety
- HS Code
- 29371900
N-Bromosuccinimide Price
- Product number
- JK1391830
- Product name
- AngiotensinItrifluoroacetatesalt
- Purity
- 98%
- Packaging
- 5mg
- Price
- $20
- Updated
- 2021/12/16
- Product number
- A1007
- Product name
- Angiotensin1/2(1-9)
- Packaging
- 5mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- JK1391830
- Product name
- AngiotensinItrifluoroacetatesalt
- Purity
- 98%
- Packaging
- 25mg
- Price
- $66
- Updated
- 2021/12/16
- Product number
- A1007
- Product name
- Angiotensin1/2(1-9)
- Packaging
- 10mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FA109440
- Product name
- Angiotensin I (1-9) trifluoroacetate salt H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-OH trifluoroacetate salt
- Packaging
- 10mg
- Price
- $114
- Updated
- 2021/12/16
H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH Chemical Properties,Usage,Production
Chemical Properties
White powder
Definition
ChEBI: Angiotensin (1-9) is a nine amino acid peptide which is formed when angiotensin converting enzyme 2 (ACE2) hydrolyzes the carboxy terminal leucine from angiotensin I. It is a anti-cardiac hypertrophy agent. It has a role as a human metabolite, a rat metabolite, an antihypertensive agent and a cardioprotective agent. It is a tautomer of an angiotensin (1-9) dizwitterion.
Biological Activity
angiotensin i/ii (1-9) is a peptide (asp-arg-val-tyr-ile-his-pro-phe-his) containing the amino acids 1-9 that are converted from angiotensin i/ii peptide.angiotensin i is formed by the action of renin on angiotensinogen, which has 12 amino acids and is an α-2-globulin produced constitutively and released into the circulation mainly by the liver. renin cleaves the peptide bond between the leucine (leu) and valine (val) residues on angiotensinogen, creating the ten-amino acid peptide angiotensin i. angiotensin i is converted to angiotensin ii (aii) through removal of two c-terminal residues by the enzymeangiotensin-converting enzyme (ace), primarily through ace within the lung.angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. angiotensin also stimulates the release of aldosterone, which promotes sodium retention in the distal nephron so that drives blood pressure up.figure1 formula of angiotensin i/ii (1-9)
References
1. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246–9. 2. Richard A. Preston. et. (1998). “Age-Race Subgroup Compared With Renin Profile as Predictors of Blood Pressure Response to Antihypertensive Therapy”. JAMA. 1998;280(13):1168-1172.3. Williams GH, Dluhy RG (2008). "Chapter 336: Disorders of the Adrenal Cortex". In Loscalzo J, Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL. Harrison's principles of internal medicine. McGraw-Hill Medical.
H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH manufacturers
- Product
- Angiotensin I 34273-12-6
- Price
- US $0.10-0.30/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-01-22