ChemicalBook > CAS DataBase List > H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH

H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH

Product Name
H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH
CAS No.
34273-12-6
Chemical Name
H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH
Synonyms
DRVYIHPFH;Angiotensin A;H2N-DRVYIHPFH-OH;ANGIOTENSIN (1-9);ANGIOTENSIN I (1-9);ANGIOTENSIN 1/2 (1-9);Des-Leu angiotensin I【human】;ALA-ARG-VAL-TYR-ILE-HIS-PRO-PHE;AngiotensinItrifluoroacetate sal;AngiotensinⅠtrifluoroacetate salt
CBNumber
CB6444417
Molecular Formula
C56H78N16O13
Formula Weight
1183.32
MOL File
34273-12-6.mol
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H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH Property

Density 
1.46±0.1 g/cm3(Predicted)
storage temp. 
-15°C
solubility 
≥118.3 mg/mL in DMSO; insoluble in EtOH; ≥51 mg/mL in H2O
form 
solid
pka
2.91±0.10(Predicted)
Sequence
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His
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Safety

HS Code 
29371900
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Frontier Specialty Chemicals
Product number
JK1391830
Product name
AngiotensinItrifluoroacetatesalt
Purity
98%
Packaging
5mg
Price
$20
Updated
2021/12/16
ApexBio Technology
Product number
A1007
Product name
Angiotensin1/2(1-9)
Packaging
5mg
Price
$60
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK1391830
Product name
AngiotensinItrifluoroacetatesalt
Purity
98%
Packaging
25mg
Price
$66
Updated
2021/12/16
ApexBio Technology
Product number
A1007
Product name
Angiotensin1/2(1-9)
Packaging
10mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA109440
Product name
Angiotensin I (1-9) trifluoroacetate salt H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-OH trifluoroacetate salt
Packaging
10mg
Price
$114
Updated
2021/12/16
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H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Definition

ChEBI: Angiotensin (1-9) is a nine amino acid peptide which is formed when angiotensin converting enzyme 2 (ACE2) hydrolyzes the carboxy terminal leucine from angiotensin I. It is a anti-cardiac hypertrophy agent. It has a role as a human metabolite, a rat metabolite, an antihypertensive agent and a cardioprotective agent. It is a tautomer of an angiotensin (1-9) dizwitterion.

Biological Activity

angiotensin i/ii (1-9) is a peptide (asp-arg-val-tyr-ile-his-pro-phe-his) containing the amino acids 1-9 that are converted from angiotensin i/ii peptide.angiotensin i is formed by the action of renin on angiotensinogen, which has 12 amino acids and is an α-2-globulin produced constitutively and released into the circulation mainly by the liver. renin cleaves the peptide bond between the leucine (leu) and valine (val) residues on angiotensinogen, creating the ten-amino acid peptide angiotensin i. angiotensin i is converted to angiotensin ii (aii) through removal of two c-terminal residues by the enzymeangiotensin-converting enzyme (ace), primarily through ace within the lung.angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. angiotensin also stimulates the release of aldosterone, which promotes sodium retention in the distal nephron so that drives blood pressure up.figure1 formula of angiotensin i/ii (1-9)

References

1. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246–9. 2. Richard A. Preston. et. (1998). “Age-Race Subgroup Compared With Renin Profile as Predictors of Blood Pressure Response to Antihypertensive Therapy”. JAMA. 1998;280(13):1168-1172.3. Williams GH, Dluhy RG (2008). "Chapter 336: Disorders of the Adrenal Cortex". In Loscalzo J, Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL. Harrison's principles of internal medicine. McGraw-Hill Medical.

H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH Preparation Products And Raw materials

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Preparation Products

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View Lastest Price from H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Angiotensin I 34273-12-6
Price
US $0.10-0.30/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-01-22

34273-12-6, H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OHRelated Search:


  • ANGIOTENSIN 1/2 (1-9)
  • ANGIOTENSIN (1-9)
  • ANGIOTENSIN I (1-9)
  • H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH
  • H2N-DRVYIHPFH-OH
  • DRVYIHPFH
  • Des-Leu angiotensin I【human】
  • L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro-L-Phe-L-His-OH
  • ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS
  • ALA-ARG-VAL-TYR-ILE-HIS-PRO-PHE
  • Angiotensin A
  • AngiotensinⅠtrifluoroacetate salt
  • AngiotensinItrifluoroacetate salt, 98%
  • AngiotensinItrifluoroacetate sal
  • Angiotensin I (1-9) trifluoroacetate salt H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-OH trifluoroacetate salt
  • H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH USP/EP/BP
  • 1-9-Angiotensin I, 5-L-isoleucine-
  • 34273-12-6
  • C56H78N16O13
  • SignalTransduction
  • peptide