ChemicalBook > CAS DataBase List > ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE

ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE

Product Name
ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE
CAS No.
53-73-6
Chemical Name
ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE
Synonyms
angiotensinamide;Angiotensin amide acetate;(ASN1,VAL5)-ANGIOTENSIN II;(Asn?,Val?)-Angiotensin II;ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE;hypertensin II, 1-amide-5-valyl;L-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE;H-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH;[ASN1,VAL5]-ANGIOTENSIN II ACOH 4H2O;H2-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH
CBNumber
CB9735222
Molecular Formula
C49H70N14O11
Formula Weight
1031.17
MOL File
53-73-6.mol
More
Less

ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE Property

Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
-15°C
pka
3.56±0.10(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FA109691
Product name
H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH
Packaging
5mg
Price
$160
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA109691
Product name
H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH
Packaging
10mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA109691
Product name
H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH
Packaging
25mg
Price
$300
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA109691
Product name
H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH
Packaging
50mg
Price
$450
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA109691
Product name
H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH
Packaging
100mg
Price
$500
Updated
2021/12/16
More
Less

ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE Chemical Properties,Usage,Production

Originator

Hypertensin,Ciba,W. Germany,1961

Definition

ChEBI: Angiotensinamide is an oligopeptide.

Manufacturing Process

48 mg (0.042 mmol) of L-asparaginyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-Lhistidyl- L-prolyl-L-phenylalanine methyl ester trihydrochloride are suspended in 0.5 ml of methanol, and treated gradually in the course of one hour with 0.3 ml of N-caustic soda solution (about 7 equivalents) so that the pH value of the solution is maintained between 10.5 and 11.5. After a further 30 minutes the solution is freed from methanol under vacuum at room temperature, adjusted with 1 N acetic acid to pH 7.4 and lyophilized. The residual mixture of free peptide and inorganic salts (79 mg) is fractionated by countercurrent distribution in the system butanol/0.1 N ammonium hydroxide. The pure octapeptide is obtained as a colorless powder which is soluble in water and methanol, more sparingly soluble in ethanol, and insoluble in acetone.

Therapeutic Function

Vasoconstrictor

General Description

Angiotensin amide (Hypertensin)is a synthetic polypeptide (1-L-aspariginyl-5-L-valine angiotensinoctapeptide) and has twice the pressor activity ofangiotensin II. It is pharmaceutically available as alyophilized powder for injection (0.5–2.5 mg diluted in500 mL of sodium chloride injection or 5% dextrose for injection)to be administered by continuous infusion. The pressoreffect of angiotensin is due to an increase in peripheralresistance; it constricts resistance vessels but has little or nostimulating action on the heart and little effect on the capacitancevessels. Angiotensin has been used as an adjunct invarious hypotensive states. It is mainly useful in controllingacute hypotension during administration of general anestheticsthat sensitize the heart to the effects of catecholamines.

ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6084
Advantage
56
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29797
Advantage
68
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5503
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9961
Advantage
55
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Fax
0571-87213919
Email
eric@peptidego.com
Country
China
ProdList
6347
Advantage
58
More
Less

View Lastest Price from ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE 53-73-6
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-05-11
Dideu Industries Group Limited
Product
ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE 53-73-6
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-12

53-73-6, ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHERelated Search:


  • ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE
  • ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE ACOH 4H2O
  • (ASN1,VAL5)-ANGIOTENSIN II
  • [ASN1,VAL5]-ANGIOTENSIN II ACOH 4H2O
  • H-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH
  • H2-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH
  • 1-L-Asparagine-5-L-valineangiotensin II
  • L-Asn-L-Arg-L-Val-L-Tyr-L-Val-L-His-L-Pro-L-Phe-OH
  • 2-[[1-[2-[[2-[[2-[[2-[[2-[(2,4-diamino-4-keto-butanoyl)amino]-5-guanidino-pentanoyl]amino]-3-methyl-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methyl-butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenyl-propionic acid
  • L-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE
  • angiotensinamide
  • hypertensin II, 1-amide-5-valyl
  • L-Phenylalanine, N-[1-[N-[N-[N-[N-(N(sup2)-L-asparaginyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-valyl]-L-histidyl]-L-prolyl]-
  • 2-[[1-[2-[[2-[[2-[[2-[[5-(diaminomethylideneamino)-2-[(2,4-diamino-4-oxobutanoyl)amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
  • 2-[[1-[2-[[2-[[2-[[2-[[5-[bis(azanyl)methylideneamino]-2-[[2,4-bis(azanyl)-4-oxo-butanoyl]amino]pentanoyl]amino]-3-methyl-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methyl-butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidin-2-yl]carbonylamino]-3-phenyl-propanoic acid
  • Angiotensin II, 1-L-asparagine-5-L-valine-
  • ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE USP/EP/BP
  • Angiotensin amide acetate
  • Angiotensin amide acetate(53-73-6 Free base)
  • (Asn?,Val?)-Angiotensin II
  • 53-73-6