SHA 68

ChemicalBook > CAS DataBase List > SHA 68

Product Name: SHA 68
CAS No.: 847553-89-3
Chemical Name: SHA 68
Synonyms: SHA 68;N-(4-fluorobenzyl)-3-oxo-1,1-diphenyltetrahydro-1H-oxazolo[3,4-a]pyrazine-7(3H)-carboxamide;N-(4-Fluorobenzyl)-3-oxo-1,1-diphenyltetrahydro-3H-oxazolo[3,4-a]pyrazine-7(1H)-carboxamide;N-[(4-Fluorophenyl)methyl]tetrahydro-3-oxo-1,1-diphenyl-3H-oxazolo[3,4-a]pyrazine-7(1H)-carboxamide;N-[(4-fluorophenyl)methyl]-3-oxo-1,1-diphenyl-hexahydro-1H-[1,3]oxazolo[3,4-a]pyrazine-7-carboxamide;3H-Oxazolo[3,4-a]pyrazine-7(1H)-carboxamide, N-[(4-fluorophenyl)methyl]tetrahydro-3-oxo-1,1-diphenyl-
CBNumber: CB73037532
Molecular Formula: C26H24FN3O3
Formula Weight: 445.49
MOL File: 847553-89-3.mol

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SHA 68 Property

Boiling point:: 727.8±60.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 16 mg/ml; DMSO: 14 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml
form: A crystalline solid
pka: 13.32±0.40(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1459
Product name: SHA 68
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $91.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1459
Product name: SHA 68
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $462
Updated: 2024/03/01

Cayman Chemical

Product number: 21512
Product name: SHA-68
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21512
Product name: SHA-68
Purity: ≥95%
Packaging: 5mg
Price: $88
Updated: 2024/03/01

Cayman Chemical

Product number: 21512
Product name: SHA-68
Purity: ≥95%
Packaging: 10mg
Price: $160
Updated: 2024/03/01

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SHA 68 Chemical Properties,Usage,Production

Description

SHA-68 is an antagonist of the neuropeptide S receptor (NPSR; IC₅₀s = 22 and 23.8 nM for the NPSR Asn¹⁰⁷ and NPSR Ile¹⁰⁷ isoforms, respectively). It is selective for NPSR over a panel of 14 G protein-coupled receptors exhibiting no activity at a concentration of 10 μM. SHA-68 (50 mg/kg) reduces NPS-induced horizontal activity and vertical rearing and climbing in mice. SHA-68 also reduces conditioned reinstatement of cocaine seeking in rats.

Uses

SHA 68 is a selective neuropeptide S antagonist.

storage

Store at +4°C

SHA 68 Preparation Products And Raw materials

Raw materials

Preparation Products

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847553-89-3, SHA 68Related Search:

SH-4-54 SH5-07

SHA 68

N-(4-fluorobenzyl)-3-oxo-1,1-diphenyltetrahydro-1H-oxazolo[3,4-a]pyrazine-7(3H)-carboxamide

N-[(4-Fluorophenyl)methyl]tetrahydro-3-oxo-1,1-diphenyl-3H-oxazolo[3,4-a]pyrazine-7(1H)-carboxamide

3H-Oxazolo[3,4-a]pyrazine-7(1H)-carboxamide, N-[(4-fluorophenyl)methyl]tetrahydro-3-oxo-1,1-diphenyl-

N-(4-Fluorobenzyl)-3-oxo-1,1-diphenyltetrahydro-3H-oxazolo[3,4-a]pyrazine-7(1H)-carboxamide

N-[(4-fluorophenyl)methyl]-3-oxo-1,1-diphenyl-hexahydro-1H-[1,3]oxazolo[3,4-a]pyrazine-7-carboxamide

847553-89-3