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Pyr10

Product Name
Pyr10
CAS No.
1315323-00-2
Chemical Name
Pyr10
Synonyms
Pyr10;PYR-10;PYR 10;Pyr10 >=98% (HPLC);Pyr10, 10 mM in DMSO;N-{4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}-4-methylbenzenesulfonamide;Benzenesulfonamide, N-[4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-;l-NAME,pyrazole,SOCE,Inhibitor,TRPC3,fibroblast,cardiac,ROCE,inhibit,Orai,STIM1,Pyr 10,Transient receptor potential channels,Ca2+,TRP Channel,Pyr10,Pyr-10
CBNumber
CB73040228
Molecular Formula
C18H13F6N3O2S
Formula Weight
449.37
MOL File
1315323-00-2.mol
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Pyr10 Property

Melting point:
105-107 °C
Boiling point:
470.1±55.0 °C(Predicted)
Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 100 mg/mL (222.53 mM);Water : < 0.1 mg/mL (insoluble)
form 
Solid
pka
6.98±0.10(Predicted)
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris
Product number
6941
Product name
Pyr10
Purity
≥98%(HPLC)
Packaging
50
Price
$545
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611723
Product name
Pyr10
Packaging
50mg
Price
$584.8
Updated
2021/12/16
ChemScene
Product number
CS-5276
Product name
Pyr10
Purity
97.52%
Packaging
50mg
Price
$432
Updated
2021/12/16
ChemScene
Product number
CS-5276
Product name
Pyr10
Purity
97.52%
Packaging
5mg
Price
$66
Updated
2021/12/16
ChemScene
Product number
CS-5276
Product name
Pyr10
Purity
97.52%
Packaging
10mg
Price
$108
Updated
2021/12/16
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Pyr10 Chemical Properties,Usage,Production

Biological Activity

Pyr10 is a novel, selective inhibitor of the transient receptor potential channel TRPC3. Pyr10 blocks carbachol-induced calcium entry into TRPC3-transfected HEK293 cells (IC50 = 0.72 μM), with significantly lower activity against STIM1/Orai1 mediated release of calcium from endoplasmic reticulum (store operated calcium entry) in BRL-2H3 cells (IC50 = 13.08 μM).

storage

Store at -20°C

Pyr10 Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyr10 Suppliers

China 48 United States 3 Global 51
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58

1315323-00-2, Pyr10Related Search:


  • Pyr10
  • N-{4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}-4-methylbenzenesulfonamide
  • PYR-10;PYR 10
  • Benzenesulfonamide, N-[4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-
  • Pyr10 >=98% (HPLC)
  • l-NAME,pyrazole,SOCE,Inhibitor,TRPC3,fibroblast,cardiac,ROCE,inhibit,Orai,STIM1,Pyr 10,Transient receptor potential channels,Ca2+,TRP Channel,Pyr10,Pyr-10
  • Pyr10, 10 mM in DMSO
  • 1315323-00-2