Glycerol phenylbutyrate
- Product Name
- Glycerol phenylbutyrate
- CAS No.
- 611168-24-2
- Chemical Name
- Glycerol phenylbutyrate
- Synonyms
- Ravicti;Glycerol phenylbutryate;glyceryl tri-(4-phenylbutyrate);HPN-100;Glycerol phenylbutyrate;Hydroxy Urea Impurity 9;HPN-100(Glycerol phenylbutyrate);Glycerol phenylbutyrate, 10 mM in DMSO;Propane-1,2,3-triyl tris(4-phenylbutanoate);BENZENEBUTANOIC ACID, 1,2,3-PROPANETRIYL ESTER
- CBNumber
- CB73049827
- Molecular Formula
- C33H38O6
- Formula Weight
- 530.65
- MOL File
- 611168-24-2.mol
Glycerol phenylbutyrate Property
- Boiling point:
- 621.2±45.0 °C(Predicted)
- Density
- 1.131±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:150.0(Max Conc. mg/mL);282.67(Max Conc. mM)
Ethanol:50.0(Max Conc. mg/mL);94.22(Max Conc. mM) - form
- Oil
- color
- Colourless
- InChIKey
- ZSDBFLMJVAGKOU-UHFFFAOYSA-N
- SMILES
- C(OC(=O)CCCC1=CC=CC=C1)C(OC(=O)CCCC1=CC=CC=C1)COC(=O)CCCC1=CC=CC=C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML3426
- Product name
- Glycerol phenylbutyrate
- Purity
- ≥95% (HPLC)
- Packaging
- 10 mg
- Price
- $63.27
- Updated
- 2025/07/31
- Product number
- SML3426
- Product name
- Glycerol phenylbutyrate
- Purity
- ≥95% (HPLC)
- Packaging
- 50 mg
- Price
- $336
- Updated
- 2025/07/31
- Product number
- T808810
- Product name
- Tri(4-phenylbutyryl)glycerol
- Packaging
- 100mg
- Price
- $260
- Updated
- 2021/12/16
- Product number
- T808810
- Product name
- Tri(4-phenylbutyryl)glycerol
- Packaging
- 25mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- CS-0017499
- Product name
- Glycerolphenylbutyrate
- Purity
- 99.81%
- Packaging
- 50mg
- Price
- $100
- Updated
- 2021/12/16
Glycerol phenylbutyrate Chemical Properties,Usage,Production
Uses
Tri(4-phenylbutyryl)glycerol is a drug that is currently under development for treatment of urea cyclic disorders (UCDs). It works by preventing the harmful buildup of ammonia in the body.
Definition
ChEBI: Glycerol phenylbutyrate is a triglyceride.
Biological Activity
Glycerol phenylbutyrate, a triacylglycerol, is a prodrug of ER stress inhibitor 4-phenylbutyric acid (PBA). Glycerol phenylbutyrate is a nitrogen-binding agent approved for the chronic management of adult and pediatric patients (≥2 years of age) with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone.
in vivo
Glycerol phenylbutyrate (GPB) has the potential for the treatment of hyperammonemia. Glycerol phenylbutyrate (GPB) may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders[1][2].
IC 50
Sigma 2 Receptor
Glycerol phenylbutyrate Preparation Products And Raw materials
Raw materials
Preparation Products
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