Cysteamine hydrochloride
- Product Name
- Cysteamine hydrochloride
- CAS No.
- 156-57-0
- Chemical Name
- Cysteamine hydrochloride
- Synonyms
- CYSTEAMINE HCL;2-AMINOETHANETHIOL HYDROCHLORIDE;2-MERCAPTOETHYLAMINE HYDROCHLORIDE;Mercaptamine hydrochloride;mercaptoethylammonium chloride;2-Mercaptoethylammonium chloride;2-AMINOETHANE-1-THIOL HYDROCHLORIDE;2-AMINOETHANETHIOL HCL;Aminoethanethiol hydrochloride;DECARBOXYCYSTEINE HYDROCHLORIDE
- CBNumber
- CB9337215
- Molecular Formula
- C2H8ClNS
- Formula Weight
- 113.61
- MOL File
- 156-57-0.mol
Cysteamine hydrochloride Property
- Melting point:
- 67-71 °C
- Boiling point:
- 238.5℃[at 101 325 Pa]
- Density
- 0.75
- vapor pressure
- 5.333Pa at 25℃
- refractive index
- 1.6100 (estimate)
- storage temp.
- 2-8°C
- solubility
- H2O: 1 m at 20 °C, clear, colorless
- form
- Crystalline Powder or Pellets
- color
- White
- PH
- 3.3-5.0 (400g/l, H2O, 20℃)
- Water Solubility
- VERY SOLUBLE
- Sensitive
- Hygroscopic
- λmax
- λ: 280 nm Amax: ≤0.3
- Merck
- 14,2779
- BRN
- 3590083
- Stability:
- Stable, but hygroscopic. Incompatible with strong oxidizing agents.
- InChIKey
- OGMADIBCHLQMIP-UHFFFAOYSA-N
- LogP
- -2.14 at 25℃
- CAS DataBase Reference
- 156-57-0(CAS DataBase Reference)
- EPA Substance Registry System
- Cysteamine hydrochloride (156-57-0)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 36/37/39-26-36
- RIDADR
- UN 3335
- WGK Germany
- 3
- RTECS
- KJ0200000
- F
- 1-3-10-13
- TSCA
- Yes
- HS Code
- 29309070
- Toxicity
- LD50 orally in Rabbit: 642 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.02835
- Product name
- Cysteaminium chloride
- Purity
- for synthesis
- Packaging
- 10g
- Price
- $44.5
- Updated
- 2024/03/01
- Product number
- 8.02835
- Product name
- Cysteaminium chloride
- Purity
- for synthesis
- Packaging
- 25g
- Price
- $55.1
- Updated
- 2024/03/01
- Product number
- 8.02835
- Product name
- Cysteaminium chloride
- Purity
- for synthesis
- Packaging
- 100g
- Price
- $148
- Updated
- 2024/03/01
- Product number
- 30078
- Product name
- Cysteamine hydrochloride
- Purity
- BioXtra
- Packaging
- 25g
- Price
- $139
- Updated
- 2024/03/01
- Product number
- A0296
- Product name
- 2-Aminoethanethiol Hydrochloride
- Purity
- >95.0%(T)
- Packaging
- 25g
- Price
- $40
- Updated
- 2024/03/01
Cysteamine hydrochloride Chemical Properties,Usage,Production
Description
Cysteamine is a stable aminothiol with radioprotective activities. It reduces ionizing radiation-induced death and chromosomal damage in mice in a dose-dependent manner. Cysteamine binds rapidly and temporarily to plasma proteins upon administration and this activity is directly correlated to its radioprotective effects. In vitro, 0.1 mM cysteamine depletes 90% of free cystine from cystinotic fibroblasts. Formulations containing cysteamine have been used to treat nephropathic cystinosis and reduce glomerular deterioration in humans.
Chemical Properties
White Solid
Uses
An inhibitor of DMBA-induced mammary tumors2-Mercaptoethylamine hydrochloride acts as a precursor in taurine biosynthesis and component of coenzyme A. It is involved in the preparation of active pharmaceutical ingredients like ranitidine and nizatidine. It acts as an antidote for acetaminophen poisoning. Further, it is used in the oral treatment of nephropathic cystinosis, radiation sickness and disorders of cysteine excretion. In addition to this, it serves as an antioxidant and an inhibitor of 7,12-Dimethylbenz[a]anthracene (DMBA)-induced tumors.
Uses
Cysteamine hydrochloride has been used in the in-situ generation of chiral cysteamine-capped cadmium sulfide quantum dots (CA-CdS QDs) for the sensing of Cd2+ and S2-.
Uses
Cysteamine hydrochloride is used as an antioxidant and in radiation therapy.
General Description
Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine.
Hazard
Toxic by inhalation and ingestion.
Biochem/physiol Actions
Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine. Cysteamine is used in a wide range of applications from regulation of gene expression, to depletion of somatostatin, to coating of nanoparticles.
Synthesis
In particular to synthesizing cysteamine hydrochloride in alkali surroundings, which is characterized in that ethanolamine solution and sulfate solution are used as raw material; 2- amino ethyl sulfate is firstly synthesized before made into ring in alkaline solution by 2-amino ethyl sulfate and carbon disulfide, thereby getting Alpha -mercaptothiazoline; alkaline hydrolysis is made upon Alpha -mercaptothiazoline to produce cysteamine hydrochloride.
Purification Methods
Purify the salt by recrystallisation from EtOH. It is freely soluble in H2O and should be stored in a dry atmosphere. [Mills & Bogert J Am Chem Soc 62 1177 1940.] The picrate has m 125-126o; see previous entry for free base. [Beilstein 4 IV 1570.]
Cysteamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Cysteamine hydrochloride manufacturers
- Product
- Cysteamine hydrochloride 156-57-0
- Price
- US $100.00-75.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 500Ton
- Release date
- 2024-08-13
- Product
- Cysteamine hydrochloride 156-57-0
- Price
- US $0.00-0.00/kg/drum kg/bag
- Min. Order
- 25kg/drum kg/bag
- Purity
- 75% 95% 99%
- Supply Ability
- 1000000MT
- Release date
- 2023-03-01
- Product
- Sodium Glycinate 6000-44-8
- Price
- US $120.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-17