ChemicalBook > CAS DataBase List > Cbz-N-amido-PEG3-acid

Cbz-N-amido-PEG3-acid

Product Name
Cbz-N-amido-PEG3-acid
CAS No.
1310327-18-4
Chemical Name
Cbz-N-amido-PEG3-acid
Synonyms
CBZ-AEEEP;CBZ-NH-PEG3-acid;Cbz-NH-PEG3-C2-acid;CbzNH-PEG3-CH2CH2COOH;CBZ-N-AMIDO-PEG3-COOH;Cbz-N-amido-PEG3-acid;CBZ-NH-PEG3-propionic acid;CBZ-12-amino-4,7,10-trioxadodecanoic acid;3-oxo-1-phenyl-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid;5,8,11-Trioxa-2-azatetradecanedioic acid, 1-(phenylmethyl) ester
CBNumber
CB73062460
Molecular Formula
C17H25NO7
Formula Weight
355.38
MOL File
1310327-18-4.mol
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Cbz-N-amido-PEG3-acid Property

storage temp. 
2-8°C
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C227223
Product name
Cbz-N-Amido-PEG3-Acid
Packaging
100mg
Price
$130
Updated
2021/12/16
BroadPharm
Product number
BP-22312
Product name
Cbz-N-amido-PEG3-acid
Purity
98%
Packaging
1g
Price
$290
Updated
2021/12/16
Ambeed
Product number
A755988
Product name
CBz-n-amido-peg3-acid
Purity
95%
Packaging
100mg
Price
$35
Updated
2021/12/16
Ambeed
Product number
A755988
Product name
CBz-n-amido-peg3-acid
Purity
95%
Packaging
250mg
Price
$64
Updated
2021/12/16
Acrotein
Product number
B-1097
Product name
CbzNH-PEG3-CH2CH2COOH
Purity
97%
Packaging
1g
Price
$165
Updated
2021/12/16
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Cbz-N-amido-PEG3-acid Chemical Properties,Usage,Production

Description

Cbz-N-amido-PEG3-acid is a PEG linker containing a CBZ-protected amino group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected by acidic conditions.

Uses

Cbz-NH-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Cbz-N-amido-PEG3-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Cbz-N-amido-PEG3-acid manufacturers

LAURENT
Product
CBZ-NH-PEG3-CH2CH2COOH 1310327-18-4
Price
US $333.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-24

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