ChemicalBook > CAS DataBase List > N106
N106
- Product Name
- N106
- CAS No.
- 862974-25-2
- Chemical Name
- N106
- Synonyms
- N106, 10 mM in DMSO;4-Methoxy-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl-2-benzothiazolamine;2-Benzothiazolamine, 4-methoxy-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-;N-(4-Methoxybenzo[d]thiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine
- CBNumber
- CB73146335
- Molecular Formula
- C17H14N4O3S
- Formula Weight
- 354.38
- MOL File
- 862974-25-2.mol
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N106 Property
- Boiling point:
- 545.4±56.0 °C(Predicted)
- Density
- 1.390±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 20 mg/ml
- form
- A solid
- pka
- 1.03±0.10(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
TRC
- Product number
- N926030
- Product name
- N106
- Packaging
- 1mg
- Price
- $130
- Updated
- 2021/12/16
Axon Medchem
- Product number
- Axon2565
- Product name
- N106
- Purity
- 99%
- Packaging
- 25mg
- Price
- $368.5
- Updated
- 2021/12/16
AK Scientific
- Product number
- 0326CK
- Product name
- N-(4-Methoxybenzo[d]thiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine
- Packaging
- 25mg
- Price
- $749
- Updated
- 2021/12/16
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N106 Chemical Properties,Usage,Production
Uses
N106 is an activator of SUMO-activating enzyme, E1 ligase.
in vivo
In a murine model, the half-life of N106 is determined to be ~65.4?min with a Cmax of ~2.24?μM when the mice received 10?mg/kg of N106 by intravenous injection. The oral bioavailability (F%) is 56% and 50%, and terminal elimination half-life (t1/2) is 19?min[1].
?
In vivo, N106 (10 mg/kg) increases cardiac SERCA2A SUMOylation, and significantly improves ventricular function in mice with heart failure[1].
N106 Preparation Products And Raw materials
Raw materials
Preparation Products
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