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Vadadustat

Product Name
Vadadustat
CAS No.
1000025-07-9
Chemical Name
Vadadustat
Synonyms
CS-2486;AKB-6548;Valdesta;PG1016548;PG-1016548;PG 1016548;Vadadustat;Vadadustat 13C6;PG-1016548;AKB-6548;Vadadustat USP/EP/BP
CBNumber
CB73147387
Molecular Formula
C14H11ClN2O4
Formula Weight
306.7
MOL File
1000025-07-9.mol
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Vadadustat Property

Melting point:
172-174°C
Boiling point:
674.6±55.0 °C(Predicted)
Density 
1.461±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.09±0.40(Predicted)
color 
Pale Beige to Light Beige
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
5mg
Price
$54
Updated
2023/01/06
Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
10mg
Price
$96
Updated
2023/01/06
Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
25mg
Price
$212
Updated
2023/01/06
Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
50mg
Price
$318
Updated
2023/01/06
TRC
Product number
V849530
Product name
Vadadustat
Packaging
5mg
Price
$195
Updated
2021/12/16
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Vadadustat Chemical Properties,Usage,Production

Description

Vadadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) and HIF-PH3 (IC50s = 1.1 and 0.39 micromolar, respectively). It stabilizes HIF-1α in mouse hepatocyte nuclear extracts. Vadadustat (50 and 100 mg/kg) increases erythropoietin levels in mouse serum.

Uses

Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.

Vadadustat Preparation Products And Raw materials

Raw materials

Preparation Products

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Vadadustat Suppliers

China 67 India 1 United States 6 Global 74
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
027-65522453
Email
sales@sun-shinechem.com
Country
China
ProdList
300
Advantage
64
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
021-64556180 15000803246
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3355
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7907
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Shanghai YuanQi Biotechnology Co., Ltd.
Tel
+86-2332782371 +86-18120098618
Email
sales@adobechem.com
Country
China
ProdList
3160
Advantage
50
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696 15000506266
Fax
+86-21-52996696
Email
2311958233@qq.com
Country
China
ProdList
3562
Advantage
55
Hangzhou Cheminspire Technology Co., Ltd.
Tel
10006559855
Fax
0571 89081561
Email
info@cheminspire.com
Country
China
ProdList
389
Advantage
58
Suzhou PengXu PharmaTech Co., Ltd.
Tel
18362508876
Email
kendoll@cqpharm.com
Country
China
ProdList
88
Advantage
58
Chengdu DingDang Pharmaceutical Co., Ltd.
Tel
028-86040038
Fax
028-85149890
Email
market@dingdangchem.com
Country
China
ProdList
1702
Advantage
55
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View Lastest Price from Vadadustat manufacturers

Wuhan Nutra Biotechnology Co.,Ltd
Product
Vadadustat 1000025-07-9
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1000kgs
Release date
2021-05-24
Career Henan Chemical Co
Product
Vadadustat 1000025-07-9
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

1000025-07-9, VadadustatRelated Search:


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  • disease,HIFs,AKB 6548,Erythropoiesis-stimulating,kidney,Inhibitor,AKB6548,inhibit,Vadadustat,HIF-PH,PG 1016548,anemia,Hypoxia-inducible factors,PG1016548,nondialysis-dependent,HIF/HIF Prolyl-Hydroxylase,chronic
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