ChemicalBook > CAS DataBase List > Vadadustat

Vadadustat

Product Name
Vadadustat
CAS No.
1000025-07-9
Chemical Name
Vadadustat
Synonyms
CS-2486;AKB-6548;Valdesta;PG1016548;PG-1016548;PG 1016548;Vadadustat;Vardorestat;Vadadustat 13C6;PG-1016548;AKB-6548
CBNumber
CB73147387
Molecular Formula
C14H11ClN2O4
Formula Weight
306.7
MOL File
1000025-07-9.mol
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Vadadustat Property

Melting point:
172-174°C
Boiling point:
674.6±55.0 °C(Predicted)
Density 
1.461±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.09±0.40(Predicted)
color 
Pale Beige to Light Beige
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P314Get medical advice/attention if you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
5mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
10mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
25mg
Price
$239
Updated
2024/03/01
Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
50mg
Price
$357
Updated
2024/03/01
TRC
Product number
V849530
Product name
Vadadustat
Packaging
5mg
Price
$195
Updated
2021/12/16
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Vadadustat Chemical Properties,Usage,Production

Description

Vadadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) and HIF-PH3 (IC50s = 1.1 and 0.39 micromolar, respectively). It stabilizes HIF-1α in mouse hepatocyte nuclear extracts. Vadadustat (50 and 100 mg/kg) increases erythropoietin levels in mouse serum.

Uses

Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.

Vadadustat Preparation Products And Raw materials

Raw materials

Preparation Products

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Vadadustat Suppliers

China 76 India 2 United States 9 Global 87
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 17702719238
Email
sales@sun-shinechem.com
Country
China
ProdList
905
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17988
Advantage
64
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
1010
Advantage
62
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3420
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7892
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4121
Advantage
55
Hangzhou Cheminspire Technology Co., Ltd.
Tel
0571-89081561; 10006559855
Fax
0571 89081561
Email
info@cheminspire.com
Country
China
ProdList
412
Advantage
58
Suzhou PengXu PharmaTech Co., Ltd.
Tel
15850786624
Email
sales@cqpharm.com
Country
China
ProdList
88
Advantage
58
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View Lastest Price from Vadadustat manufacturers

Wuhan Nutra Biotechnology Co.,Ltd
Product
Vadadustat 1000025-07-9
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1000kgs
Release date
2021-05-24
Career Henan Chemical Co
Product
Vadadustat 1000025-07-9
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

1000025-07-9, VadadustatRelated Search:


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