ChemicalBook > CAS DataBase List > Fmoc-PEG12-NHS ester
Fmoc-PEG12-NHS ester
- Product Name
- Fmoc-PEG12-NHS ester
- CAS No.
- 2227246-92-4
- Chemical Name
- Fmoc-PEG12-NHS ester
- Synonyms
- Fmoc-NH-PEG12-NHS;Fmoc-PEG12-NHS ester;FmocNH-PEG12-NHS?ester;FmocNH-PEG12-CH2CH2COONHS;Inhibitor,Fmoc-PEG-12-NHS ester,FmocPEG12NHS ester,PROTAC Linkers,Fmoc PEG12 NHS ester,inhibit;2,5-Dioxopyrrolidin-1-yl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oate;5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester;FmocNH-PEG12-CH2CH2COONHS/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester
- CBNumber
- CB73162964
- Molecular Formula
- C46H68N2O18
- Formula Weight
- 937.03
- MOL File
- 2227246-92-4.mol
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Fmoc-PEG12-NHS ester Property
- storage temp.
- Storage temp. -20°C
- solubility
- Soluble in DCM
- form
- Viscous Liquid
- color
- Colorless to light yellow
- InChIKey
- HQKUPHFWWTZASE-UHFFFAOYSA-N
- SMILES
- C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(=O)CCC1=O)=O
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N-Bromosuccinimide Price
Apolloscientific
- Product number
- BIPG1422
- Product name
- Fmoc-PEG12-NHS ester
- Packaging
- 100mg
- Price
- $623
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22241
- Product name
- Fmoc-PEG12-NHSester
- Purity
- 95%
- Packaging
- 500mg
- Price
- $650
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22241
- Product name
- Fmoc-PEG12-NHSester
- Purity
- 95%
- Packaging
- 1g
- Price
- $860
- Updated
- 2021/12/16
Activate Scientific
- Product number
- AS107822
- Product name
- FmocNH-PEG12-CH2CH2COONHS
- Purity
- 97%
- Packaging
- 1g
- Price
- $969
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22241
- Product name
- Fmoc-PEG12-NHSester
- Purity
- 95%
- Packaging
- 2g
- Price
- $1290
- Updated
- 2021/12/16
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Fmoc-PEG12-NHS ester Chemical Properties,Usage,Production
Description
Fmoc-PEG12-NHS ester is a PEG linker containing an Fmoc-protected amine and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Uses
Fmoc-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fmoc-PEG12-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Fmoc-PEG12-NHS ester manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- FmocNH-PEG12-NHS ester 2227246-92-4
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >99.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25