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Fmoc-PEG12-NHS ester

Product Name
Fmoc-PEG12-NHS ester
CAS No.
2227246-92-4
Chemical Name
Fmoc-PEG12-NHS ester
Synonyms
Fmoc-NH-PEG12-NHS;Fmoc-PEG12-NHS ester;FmocNH-PEG12-NHS?ester;FmocNH-PEG12-CH2CH2COONHS;Inhibitor,Fmoc-PEG-12-NHS ester,FmocPEG12NHS ester,PROTAC Linkers,Fmoc PEG12 NHS ester,inhibit;2,5-Dioxopyrrolidin-1-yl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oate;5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester;FmocNH-PEG12-CH2CH2COONHS/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester
CBNumber
CB73162964
Molecular Formula
C46H68N2O18
Formula Weight
937.03
MOL File
2227246-92-4.mol
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Fmoc-PEG12-NHS ester Property

storage temp. 
Storage temp. -20°C
solubility 
Soluble in DCM
form 
Viscous Liquid
color 
Colorless to light yellow
InChIKey
HQKUPHFWWTZASE-UHFFFAOYSA-N
SMILES
C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(=O)CCC1=O)=O
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Apolloscientific
Product number
BIPG1422
Product name
Fmoc-PEG12-NHS ester
Packaging
100mg
Price
$623
Updated
2021/12/16
BroadPharm
Product number
BP-22241
Product name
Fmoc-PEG12-NHSester
Purity
95%
Packaging
500mg
Price
$650
Updated
2021/12/16
BroadPharm
Product number
BP-22241
Product name
Fmoc-PEG12-NHSester
Purity
95%
Packaging
1g
Price
$860
Updated
2021/12/16
Activate Scientific
Product number
AS107822
Product name
FmocNH-PEG12-CH2CH2COONHS
Purity
97%
Packaging
1g
Price
$969
Updated
2021/12/16
BroadPharm
Product number
BP-22241
Product name
Fmoc-PEG12-NHSester
Purity
95%
Packaging
2g
Price
$1290
Updated
2021/12/16
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Fmoc-PEG12-NHS ester Chemical Properties,Usage,Production

Description

Fmoc-PEG12-NHS ester is a PEG linker containing an Fmoc-protected amine and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Fmoc-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Fmoc-PEG12-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-PEG12-NHS ester Suppliers

Adachibio Inc.
Tel
+81-8027837258; +8108027837258
Fax
0081-80278372055
Email
sales@adachibio.com
Country
Japan
ProdList
992
Advantage
58
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View Lastest Price from Fmoc-PEG12-NHS ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
FmocNH-PEG12-NHS ester 2227246-92-4
Price
US $0.00/g
Min. Order
1g
Purity
>99.00%
Supply Ability
1g
Release date
2024-03-25

2227246-92-4, Fmoc-PEG12-NHS esterRelated Search:


  • Fmoc-PEG12-NHS ester
  • FmocNH-PEG12-NHS?ester
  • FmocNH-PEG12-CH2CH2COONHS
  • 5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester
  • Fmoc-NH-PEG12-NHS
  • Inhibitor,Fmoc-PEG-12-NHS ester,FmocPEG12NHS ester,PROTAC Linkers,Fmoc PEG12 NHS ester,inhibit
  • FmocNH-PEG12-CH2CH2COONHS/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester
  • 2,5-Dioxopyrrolidin-1-yl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oate
  • 2227246-92-4
  • C46H68N2O18