ChemicalBook > CAS DataBase List > Pyrene -PEG3-azide

Pyrene -PEG3-azide

Product Name
Pyrene -PEG3-azide
CAS No.
1817735-36-6
Chemical Name
Pyrene -PEG3-azide
Synonyms
Pyrene-PEG3-N3;Pyrene -PEG3-azide;Pyrene-amido-PEG4-azide;1-Pyrenecarboxamide, N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-4,6-dihydro-
CBNumber
CB73163123
Molecular Formula
C25H28N4O4
Formula Weight
448.52
MOL File
1817735-36-6.mol
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Pyrene -PEG3-azide Property

solubility 
Soluble in DMSO, DMF, DCM
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22916
Product name
Pyrene-PEG3-azide
Purity
98%
Packaging
1mg
Price
$180
Updated
2021/12/16
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Pyrene -PEG3-azide Chemical Properties,Usage,Production

Description

Pyrene-PEG3-azide is a pyrene labeled PEG linker containing an azide group, which enables Click Chemistry labeling with any alkyne-bearing molecules and thus turns any molecule into pyrene-bearing probe.

Uses

Pyrene-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Pyrene-amido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Pyrene -PEG3-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyrene -PEG3-azide Suppliers

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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0431-0431-80514535 19917294565
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China
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Jinan elephant international trading co., LTD
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Zhengzhou Acme Chemical Co., Ltd.
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0371-037163312495,13303845143 13303845143
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Alpha Biopharmaceuticals Co., Ltd
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0411-39042497
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0411-39042693
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sales@alphabiopharm.com
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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Nextpeptide Inc
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+86-0571-81612335 +8613336028439
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
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Hangzhou Taorui Biotechnology Co., Ltd
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4000-360-990 15268198094
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Zhengzhou convergence chemical co., LTD
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 15801484223;
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psaitong@jm-bio.com
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