Pyrene -PEG3-azide

Product Name: Pyrene -PEG3-azide
CAS No.: 1817735-36-6
Chemical Name: Pyrene -PEG3-azide
Synonyms: Pyrene-PEG3-N3;Pyrene -PEG3-azide;Pyrene-amido-PEG4-azide;1-Pyrenecarboxamide, N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-4,6-dihydro-
CBNumber: CB73163123
Molecular Formula: C25H28N4O4
Formula Weight: 448.52
MOL File: 1817735-36-6.mol

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Pyrene -PEG3-azide Property

solubility: Soluble in DMSO, DMF, DCM

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22916
Product name: Pyrene-PEG3-azide
Purity: 98%
Packaging: 1mg
Price: $180
Updated: 2021/12/16

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Pyrene -PEG3-azide Chemical Properties,Usage,Production

Description

Pyrene-PEG3-azide is a pyrene labeled PEG linker containing an azide group, which enables Click Chemistry labeling with any alkyne-bearing molecules and thus turns any molecule into pyrene-bearing probe.

Uses

Pyrene-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Pyrene-amido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Pyrene -PEG3-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyrene -PEG3-azide Suppliers

China 15 United States 2 Global 17

Jinan elephant international trading co., LTD

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TargetMol Chemicals Inc.

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Nextpeptide Inc

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Beijing Jin Ming Biotechnology Co., Ltd.

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1817735-36-6, Pyrene -PEG3-azideRelated Search:

Pyrene -PEG4-acid 3H-IndoliuM, 2-[5-[1-[6-[(3-azidopropyl)aMino]-6-oxohexyl]-1,3-dihydro-3,3-diMethyl-5-sulfo-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1,3,3-triMethyl-5-sulfo-, inner salt DNP-PEG3-azide Azidoacetic acid NHS ester Methylamino-PEG3-azide Fluorescein-PEG2-Azide BDP FL azide diSulfo-Cy5 azide Fluorescein-PEG4-azide Lipoamido-PEG3-Azide FAM azide, 6-isomer Pyrene-PEG4-Propargyl Pyrene -PEG5-OH Pyrene -PEG5-propargyl Pyrene-PEG3-Propargyl Pyrene -PEG2-azide Pyrene-PEG4-OH Pyrene-PEG4-N3

Pyrene-PEG3-N3

Pyrene -PEG3-azide

Pyrene-amido-PEG4-azide

1-Pyrenecarboxamide, N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-4,6-dihydro-

1817735-36-6