Methylamino-PEG3-azide

Product Name: Methylamino-PEG3-azide
CAS No.: 1355197-57-7
Chemical Name: Methylamino-PEG3-azide
Synonyms: N3-PEG3-NH-Me;N3-PEG3-CH2CH2NHMe;Methylamino-PEG3-N3;Methylamino-PEG3-azide;N3-PEG3-CH2CH2NHMe/Ethanamine, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-N-methyl-
CBNumber: CB73062556
Molecular Formula: C9H20N4O3
Formula Weight: 232.28
MOL File: 1355197-57-7.mol

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Methylamino-PEG3-azide Property

solubility: Soluble in Water, DMSO, DCM, DMF

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: M563183
Product name: Methylamino-PEG3-azide
Packaging: 5mg
Price: $45
Updated: 2021/12/16

BroadPharm

Product number: BP-22907
Product name: Methylamino-PEG3-azide
Purity: 98%
Packaging: 500mg
Price: $560
Updated: 2021/12/16

BroadPharm

Product number: BP-22907
Product name: Methylamino-PEG3-azide
Purity: 98%
Packaging: 1g
Price: $950
Updated: 2021/12/16

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Methylamino-PEG3-azide Chemical Properties,Usage,Production

Description

Methylamino-PEG3-azide is a PEG linker containing an azide group with a methylamine group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc.

Uses

Methylamino-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Methylamino-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Methylamino-PEG3-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Methylamino-PEG3-azide Suppliers

China 25 United States 3 Global 28

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-0431-80514535 19917294565
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Jinan elephant international trading co., LTD

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Amatek Scientific Co. Ltd.

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Xi'an Confluore Biological Technology Co., Ltd.

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Alfa Chemistry

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TargetMol Chemicals Inc.

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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Shanghai Minhan Pharmaceutical Technology Co., Ltd.

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Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
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Hangzhou Taorui Biotechnology Co., Ltd

Tel: 4000-360-990 15268198094
Email: sales@torreybio.com
Country: China
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View Lastest Price from Methylamino-PEG3-azide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Methylamino-PEG3-azide 1355197-57-7
Price: US $0.00/mg
Min. Order: 100mg
Purity: >95.00%
Supply Ability: 100mg
Release date: 2024-03-22

1355197-57-7, Methylamino-PEG3-azideRelated Search:

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Methylamino-PEG3-azide

N3-PEG3-CH2CH2NHMe

Methylamino-PEG3-N3

N3-PEG3-CH2CH2NHMe/Ethanamine, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-N-methyl-

N3-PEG3-NH-Me

1355197-57-7

C9H20N4O3