Pyrene -PEG3-azide
- Product Name
- Pyrene -PEG3-azide
- CAS No.
- 1817735-36-6
- Chemical Name
- Pyrene -PEG3-azide
- Synonyms
- Pyrene-PEG3-N3;Pyrene -PEG3-azide;Pyrene-amido-PEG4-azide;1-Pyrenecarboxamide, N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-4,6-dihydro-
- CBNumber
- CB73163123
- Molecular Formula
- C25H28N4O4
- Formula Weight
- 448.52
- MOL File
- 1817735-36-6.mol
Pyrene -PEG3-azide Property
- solubility
- Soluble in DMSO, DMF, DCM
N-Bromosuccinimide Price
- Product number
- BP-22916
- Product name
- Pyrene-PEG3-azide
- Purity
- 98%
- Packaging
- 1mg
- Price
- $180
- Updated
- 2021/12/16
Pyrene -PEG3-azide Chemical Properties,Usage,Production
Description
Pyrene-PEG3-azide is a pyrene labeled PEG linker containing an azide group, which enables Click Chemistry labeling with any alkyne-bearing molecules and thus turns any molecule into pyrene-bearing probe.
Uses
Pyrene-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Pyrene-amido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Pyrene -PEG3-azide Preparation Products And Raw materials
Raw materials
Preparation Products
Pyrene -PEG3-azide Suppliers
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- +1-781-999-5354; +17819995354
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- United States
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