BETULINIC ACID METHYL ESTER
- Product Name
- BETULINIC ACID METHYL ESTER
- CAS No.
- 2259-06-5
- Chemical Name
- BETULINIC ACID METHYL ESTER
- Synonyms
- Methylbetulinate;betulinate, Methyl;BETULINIC ACID METHYL ESTER;BETULINIC ACID METHYL ESTER hplc;BETULINIC ACID METHYLESTER WITH HPLC;3B-HYDROXY-LUP-20(29)-EN-28-OIC ACID METHYL ESTER;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3β)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3beta)-
- CBNumber
- CB7322703
- Molecular Formula
- C31H50O3
- Formula Weight
- 470.73
- MOL File
- 2259-06-5.mol
BETULINIC ACID METHYL ESTER Property
- Melting point:
- 222-223°C
- Boiling point:
- 523.5±33.0 °C(Predicted)
- Density
- 1.036±0.06 g/cm3(Predicted)
- pka
- 15.16±0.70(Predicted)
- form
- A solid
- LogP
- 9.400 (est)
N-Bromosuccinimide Price
- Product number
- 30066
- Product name
- Betulinic Acid methyl ester
- Packaging
- 1mg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 30066
- Product name
- Betulinic Acid methyl ester
- Packaging
- 5mg
- Price
- $456
- Updated
- 2024/03/01
- Product number
- B330253
- Product name
- BetulinicAcidMethylEster
- Packaging
- 0.5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB66104
- Product name
- Betulinic acid methyl ester
- Packaging
- 25mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FB66104
- Product name
- Betulinic acid methyl ester
- Packaging
- 50mg
- Price
- $137.5
- Updated
- 2021/12/16
BETULINIC ACID METHYL ESTER Chemical Properties,Usage,Production
Description
Betulinic acid methyl ester is a lupane-type triterpenoid and an esterified version of betulinic acid that has been found in Helicteres hirsuta and has diverse biological activities. It inhibits HIV-1 reverse transcriptase (IC50 = 11 μM). Betulinic acid methyl ester is active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively). It induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM). Betulinic acid methyl ester is cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively).
Uses
Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity[1].
Definition
ChEBI: Betulinic acid methyl ester is a triterpenoid.
Biological Activity
Betulinic acid methyl ester is a natural compound extracted from the bark of the birch tree with anti-inflammatory and antiprotozoal activity. Studies have shown it to be a potent inhibitor of cancer cell growth in vitro and in vivo. It has also been shown to have hypoglycaemic effects in mice.
References
[1] D B Domínguez-Carmona, et al. Antiprotozoal activity of betulinic acid derivatives. Phytomedicine. 2010 Apr;17(5):379-82. DOI:10.1016/j.phymed.2009.08.002
BETULINIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from BETULINIC ACID METHYL ESTER manufacturers
- Product
- BETULINIC ACID METHYL ESTER 2259-06-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-04