ChemicalBook > CAS DataBase List > BETULINIC ACID METHYL ESTER

BETULINIC ACID METHYL ESTER

Product Name: BETULINIC ACID METHYL ESTER
CAS No.: 2259-06-5
Chemical Name: BETULINIC ACID METHYL ESTER
Synonyms: Methylbetulinate;betulinate, Methyl;BETULINIC ACID METHYL ESTER;BETULINIC ACID METHYL ESTER hplc;BETULINIC ACID METHYLESTER WITH HPLC;3B-HYDROXY-LUP-20(29)-EN-28-OIC ACID METHYL ESTER;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3β)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3beta)-
CBNumber: CB7322703
Molecular Formula: C31H50O3
Formula Weight: 470.73
MOL File: 2259-06-5.mol

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BETULINIC ACID METHYL ESTER Property

Melting point:: 222-223°C
Boiling point:: 523.5±33.0 °C(Predicted)
Density: 1.036±0.06 g/cm3(Predicted)
pka: 15.16±0.70(Predicted)
form: A solid
LogP: 9.400 (est)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 30066
Product name: Betulinic Acid methyl ester
Packaging: 1mg
Price: $153
Updated: 2024/03/01

Cayman Chemical

Product number: 30066
Product name: Betulinic Acid methyl ester
Packaging: 5mg
Price: $456
Updated: 2024/03/01

TRC

Product number: B330253
Product name: BetulinicAcidMethylEster
Packaging: 0.5mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB66104
Product name: Betulinic acid methyl ester
Packaging: 25mg
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB66104
Product name: Betulinic acid methyl ester
Packaging: 50mg
Price: $137.5
Updated: 2021/12/16

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BETULINIC ACID METHYL ESTER Chemical Properties,Usage,Production

Description

Betulinic acid methyl ester is a lupane-type triterpenoid and an esterified version of betulinic acid that has been found in Helicteres hirsuta and has diverse biological activities. It inhibits HIV-1 reverse transcriptase (IC₅₀ = 11 μM). Betulinic acid methyl ester is active against L. braziliensis and T. cruzi (IC₅₀s = 69.9 and 93.3 μM, respectively). It induces melanogenesis in (EC₅₀ = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC₅₀ = 4.9 μM). Betulinic acid methyl ester is cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC₅₀s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively).

Uses

Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity[1].

Definition

ChEBI: Betulinic acid methyl ester is a triterpenoid.

Biological Activity

Betulinic acid methyl ester is a natural compound extracted from the bark of the birch tree with anti-inflammatory and antiprotozoal activity. Studies have shown it to be a potent inhibitor of cancer cell growth in vitro and in vivo. It has also been shown to have hypoglycaemic effects in mice.

References

[1] D B Domínguez-Carmona, et al. Antiprotozoal activity of betulinic acid derivatives. Phytomedicine. 2010 Apr;17(5):379-82. DOI:10.1016/j.phymed.2009.08.002

BETULINIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from BETULINIC ACID METHYL ESTER manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: BETULINIC ACID METHYL ESTER 2259-06-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-04

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