ChemicalBook > CAS DataBase List > Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester
Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester
- Product Name
- Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester
- CAS No.
- 88039-46-7
- Chemical Name
- Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester
- Synonyms
- INF 4E;NLRP3-IN-9, 10 mM in DMSO;Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate;Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester;Benzenepropanoic acid, 2-chloro-β-hydroxy-α-methylene-, ethyl ester;inflammasome,NOD-like Receptor (NLR),myocardial injury,NLRP3 IN 9,caspase-1,dysfunction,NLRP3IN9,Inhibitor,pyroptosis,inhibit,NLRP-3-IN-9,THP-1 cells
- CBNumber
- CB73270199
- Molecular Formula
- C12H13ClO3
- Formula Weight
- 240.68282
- MOL File
- 88039-46-7.mol
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Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Property
- Boiling point:
- 180-185 °C(Press: 10 Torr)
- Density
- 1.222±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 12.51±0.20(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
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N-Bromosuccinimide Price
Tocris
- Product number
- 6172
- Product name
- INF4E
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $208
- Updated
- 2021/12/16
TRC
- Product number
- I496003
- Product name
- INF4E
- Packaging
- 1g
- Price
- $1010
- Updated
- 2021/12/16
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Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Chemical Properties,Usage,Production
Uses
INF 4E was used to study the electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis.
in vivo
INF4E significantly reduces the in infarct size and lactate dehydrogenase release and improvement in postischemic left ventricular pressure[1].
INF4E attenuates the formation of NLRP3 inflammasome complex was induced by myocardial IR (ischemia/reperfusion) in a time-dependent way[1].
IC 50
NLRP3
storage
Store at -20°C
Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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