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POPC

Product Name
POPC
CAS No.
26853-31-6
Chemical Name
POPC
Synonyms
1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1-Palmitoyl-2-oleoyl-sn-glycero-3-PC;L-BETA-OLEOYL-GAMMA-PALMITOYL-ALPHA-LECITHIN;1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine;POPC;3-sn-Phospha;16:0-18:1 PC;2-oleoyl-1-palmitoyl;50-60% ALPHA, VINYL CARBONS);L-β-Oleoyl-γ-palmitoyl-α-lecithin
CBNumber
CB7328336
Molecular Formula
C42H82NO8P
Formula Weight
760.08
MOL File
26853-31-6.mol
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POPC Property

Melting point:
-3 °C
storage temp. 
-20°C
solubility 
Ethanol: 25mg/ml
form 
A crystalline solid
color 
White to off-white
BRN 
4173237
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
F 
1-8-10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H372Causes damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
42773
Product name
2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine
Purity
≥99.0% (TLC)
Packaging
100mg
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
42773
Product name
2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine
Purity
≥99.0% (TLC)
Packaging
500mg
Price
$454
Updated
2024/03/01
Cayman Chemical
Product number
15102
Product name
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
Purity
≥98%
Packaging
100mg
Price
$76
Updated
2024/03/01
Cayman Chemical
Product number
15102
Product name
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
Purity
≥98%
Packaging
250mg
Price
$179
Updated
2024/03/01
Sigma-Aldrich
Product number
P3017
Product name
2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine
Purity
≥95.5% (GC), ≥98% (TLC)
Packaging
10mg
Price
$215
Updated
2024/03/01
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POPC Chemical Properties,Usage,Production

Description

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC) is a phospholipid containing 16:0 and 18:1 fatty acids at the sn-1 and sn-2 positions, respectively. It belongs to a class of phospholipids that are a major component of biological membranes. This compound can be used for liposome production in order to study the properties of lipid bilayers.

Description

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPhtCho), is a phosphatidylcholine, that belongs to a class of phospholipids that are a major component of biological membranes. This compound has been shown to decrease the expression of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor subunit GluR1 on the plasma membrane of CA1 region of rat hippocampal slices.

Uses

16:0-18:1 PC has been used in the preparation of liposomes for the muramyl tripeptide encapsulation. It has also been used in the preparation of membrane scaffold protein 1 nanodisc. 16:0-18:1 PC may be used in the synthesis of discoidal reconstituted high-density lipoproteins.

Uses

The effect of non-ionic detergent on liposomes was studied with giant POPC liposomes. Increasing concentrations of detergent cause tubular protrusions, then indentations, to develop on spherical liposomes. At higher detergent concentrations, the liposomes burst.

Uses

Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.

Application

POPC is an important phospholipid for biophysical experiments and has been used to study various subjects such as lipid rafts. POPC is also used in systems mimicking the cell membrane such as Nanodiscs. It is available commercially synthetically and is naturally present in eukaryotic cell membranes.

Definition

ChEBI: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine is a phosphatidylcholine 34:1 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl) and 9Z-octadecenoyl (oleoyl) respectively. It has a role as a mouse metabolite. It is a phosphatidylcholine 34:1 and a 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine betaine. It is functionally related to a hexadecanoic acid and an oleic acid.

General Description

POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.

Biochem/physiol Actions

1-palmitoyl-2-oleoyl-glycero-3-phosphocholine (POPC)or 16:0-18:1 PC plays an important role as a lung surfactant and reduces surface tension. POPC mimics natural cell membrane and may be useful for unsaturated lipids oxidation studies. Its interaction with ozone leads to oxidative decomposition at the oleoyl strand C-C moiety.

POPC Preparation Products And Raw materials

Raw materials

Preparation Products

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POPC Suppliers

China 124 Germany 1 India 1 Japan 1 Sweden 1 Switzerland 4 United Kingdom 4 United States 18 Global 154
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View Lastest Price from POPC manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
POPC 26853-31-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04
Hebei Mujin Biotechnology Co.,Ltd
Product
POPC 26853-31-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-16
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 26853-31-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

26853-31-6, POPCRelated Search:

ELAIDIC ACID METHYL ESTER 1-O-HEXADECYL-SN-GLYCEROL 1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Choline hydroxide L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, LAUROYL 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE ELAIDIC ACID ELAIDIC ACID ETHYL ESTER Tetramethylammonium hydroxide pentahydrate 2-[[(2R)-3-decanoyloxy-2-hydroxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium PALMITELAIDIC ACID 1-HEXADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOETHANOLAMINE 1,2-1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE L-ALPHA-LECITHIN L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, CAPROYL 1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE 1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE 1-HEXADECYL LYSOPHOSPHATIDIC ACID

  • 3-SN-PHOSPHATIDYLCHOLINE, 2-OLEOYL-1-PALMITOYL
  • L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-OLEOYL-GAMMA-PALMITOYL
  • L-BETA-OLEOYL-GAMMA-PALMITOYL-ALPHA-LECITHIN
  • 3,5,8-Trioxa-4-phosphahexacos-17-en-1-aMiniuM,4-hydroxy-N,N,N-triMethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]Methyl]-, inner salt,4-oxide, (7R,17Z)-
  • (7R,17Z)-4-Hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium 4-oxide, inner salt
  • 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
  • 3-sn-Phospha
  • 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
  • 1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;16:0-18:1 PC
  • 1-palmitoyl-2-oleoyl-glycero-3-phosphocholine
  • L-β-Oleoyl-γ-palmitoyl-α-lecithin
  • (R)-(Z)-[4-oxido-9-oxo-7-(palmitoylmethyl)-3,5,8-trioxa-4-phosphahexacos-17-enyl)trimethylammonium 4-oxide
  • 1-Palmitoyl-2-Oleoyl-L-a-Lecithin
  • 1-Palmitoyl-2-oleyl-sn-glycero-3-phosphocholine
  • L-b-Oleoyl-g-palmitoyl-a-lecithin
  • 1-Palmityl-2-oleoyl-sn-glycero-3-phosphocholine
  • 3-sn-Phosphatidylcholine, 2-oleoyl-1-palmitoyl, L-β-Oleoyl-γ-palmitoyl-α-lecithin, 1-Hexadecanoyl-2-(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine
  • [O-(1-O-Palmitoyl-2-O-oleoyl-L-glycero-3-phospho)choline]anion
  • 1-Palmitoyl-2-oleoylplasmenylcholine
  • β-Oleoyl-γ-palmitoyl-L-α-phosphatidylcholine
  • 2-oleoyl-1-palmitoyl
  • PalMitoyl-2-oleoyl-sn-glycero-3-phosphocholine L-1618
  • 1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
  • 1-HEXADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 2-OLEOYL-1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 16:0-18:1 PC
  • POPC
  • 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine >=99.0% (TLC)
  • 1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE (FATTY ACIDS-D63,97%
  • 50-60% ALPHA, VINYL CARBONS)
  • 1-Palmitoyl-2-oleoyl-sn-3-phosphocholine
  • L-β-Oleoyl-γ-palmitoyl-α-lecithin
  • (R,Z)-2-(Oleoyloxy)-3-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
  • 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (main component of Egg Phosphatidylcholines / EPC, CAS 97281-44-2)
  • 2H5]-1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
  • POPC 1-palmitoyl-2-octyl phosphatidylcholine
  • 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphorylcholine (POPC), Zwitterionic phospholipid
  • 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (main component of Egg Phosphatidylcholines / EPC,
  • 26853-31-6
  • C42H82NO8P
  • Phosphoglycerides
  • Glycerophosphonocholines
  • Glycerides
  • Lipids
  • BioChemical
  • Biochemicals and Reagents