POPC
- Product Name
- POPC
- CAS No.
- 26853-31-6
- Chemical Name
- POPC
- Synonyms
- 1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1-Palmitoyl-2-oleoyl-sn-glycero-3-PC;L-BETA-OLEOYL-GAMMA-PALMITOYL-ALPHA-LECITHIN;1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine;POPC;3-sn-Phospha;16:0-18:1 PC;2-oleoyl-1-palmitoyl;50-60% ALPHA, VINYL CARBONS);L-β-Oleoyl-γ-palmitoyl-α-lecithin
- CBNumber
- CB7328336
- Molecular Formula
- C42H82NO8P
- Formula Weight
- 760.08
- MOL File
- 26853-31-6.mol
POPC Property
- Melting point:
- -3 °C
- storage temp.
- -20°C
- solubility
- Ethanol: 25mg/ml
- form
- A crystalline solid
- BRN
- 4173237
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H336May cause drowsiness or dizziness
H351Suspected of causing cancer
H372Causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P273Avoid release to the environment.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 42773
- Product name
- 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine
- Purity
- ≥99.0% (TLC)
- Packaging
- 100mg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 42773
- Product name
- 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine
- Purity
- ≥99.0% (TLC)
- Packaging
- 500mg
- Price
- $454
- Updated
- 2024/03/01
- Product number
- 15102
- Product name
- 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $76
- Updated
- 2024/03/01
- Product number
- 15102
- Product name
- 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $179
- Updated
- 2024/03/01
- Product number
- P3017
- Product name
- 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine
- Purity
- ≥95.5% (GC), ≥98% (TLC)
- Packaging
- 10mg
- Price
- $215
- Updated
- 2024/03/01
POPC Chemical Properties,Usage,Production
Description
1-
Description
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPhtCho), is a phosphatidylcholine, that belongs to a class of phospholipids that are a major component of biological membranes. This compound has been shown to decrease the expression of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor subunit GluR1 on the plasma membrane of CA1 region of rat hippocampal slices.
Uses
16:0-18:1 PC has been used in the preparation of liposomes for the muramyl tripeptide encapsulation. It has also been used in the preparation of membrane scaffold protein 1 nanodisc. 16:0-18:1 PC may be used in the synthesis of discoidal reconstituted high-density lipoproteins.
Uses
The effect of non-ionic detergent on liposomes was studied with giant POPC liposomes. Increasing concentrations of detergent cause tubular protrusions, then indentations, to develop on spherical liposomes. At higher detergent concentrations, the liposomes burst.
Uses
Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.
Application
POPC is an important phospholipid for biophysical experiments and has been used to study various subjects such as lipid rafts. POPC is also used in systems mimicking the cell membrane such as Nanodiscs. It is available commercially synthetically and is naturally present in eukaryotic cell membranes.
Definition
ChEBI: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine is a phosphatidylcholine 34:1 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl) and 9Z-octadecenoyl (oleoyl) respectively. It has a role as a mouse metabolite. It is a phosphatidylcholine 34:1 and a 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine betaine. It is functionally related to a hexadecanoic acid and an oleic acid.
General Description
POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.
Biochem/physiol Actions
1-palmitoyl-2-oleoyl-glycero-3-phosphocholine (POPC)or 16:0-18:1 PC plays an important role as a lung surfactant and reduces surface tension. POPC mimics natural cell membrane and may be useful for unsaturated lipids oxidation studies. Its interaction with ozone leads to oxidative decomposition at the oleoyl strand C-C moiety.
POPC Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from POPC manufacturers
- Product
- POPC 26853-31-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-10-16
- Product
- POPC 26853-31-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2023-03-23
- Product
- 1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 26853-31-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10