Ceftobiprole Medocaril Sodium Sterile Powder
- Product Name
- Ceftobiprole Medocaril Sodium Sterile Powder
- CAS No.
- 252188-71-9
- Chemical Name
- Ceftobiprole Medocaril Sodium Sterile Powder
- Synonyms
- BAL5788 sodium;Ceftobiprol medocaril;CEFTOBIPROLE MEDOCARIL SODIUM;Ceftobiprole medocaril sodium;Ceftobiprole Medocaril Sodium Sterile Powder;Sodium (6R,7R)-3-((E)-(1-((R)-1-(((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)pyrrolidin-3-yl)-2-oxopyrrolidin-3-ylidene)methyl)-7-((Z)-2-(5-amin
- CBNumber
- CB73311692
- Molecular Formula
- C26H27N8NaO11S2
- Formula Weight
- 714.66
- MOL File
- 252188-71-9.mol
Ceftobiprole Medocaril Sodium Sterile Powder Property
- storage temp.
- 4°C, away from moisture and light
- solubility
- DMSO : 250 mg/mL (350.81 mM; Need ultrasonic)
- form
- Solid
- color
- Off-white to light yellow
- InChIKey
- UKULSYNDTFCVEY-ATILTDJWNA-N
- SMILES
- C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3=NSC(N)=N3)=N\O)C(=O)N12)/C=C1\CCN([C@@H]2CCN(C(=O)OCC3=C(OC(=O)O3)C)C2)C\1=O)(=O)O.[NaH] |&1:5,7,28,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P285In case of inadequate ventilation wear respiratory protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P321Specific treatment (see … on this label).
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
Ceftobiprole Medocaril Sodium Sterile Powder Chemical Properties,Usage,Production
Uses
Broad spectrum antibiotic.
in vivo
Ceftobiprole medocaril (s.c.; 3 × q12h; total daily doses of BAL9141 equivalents, 2.1, 4.2, or 8.4 mg/kg) causes ten-day cumulative survival rates ranged from 57 to 100% for female Swiss albino mice (body weight, 20 to 22 g) infected Penr Cros Ctxs strain P-15986[1].
Ceftobiprole medocaril (10, 40, 160 mg/kg; single dose; sc) has T1/2s from 20 min to 31 min, as the dose rose from 40 mg/kg to 160 mg/kg. The AUC/dose values for the escalating single doses ranges from 0.585 to 1.33, and the Cmax/dose values decreases from 1.08 to 0.90 in neutropenic thigh-infected mice[2].
Drug interactions
Potentially hazardous interactions with other drugs
Anticoagulants: effects of coumarins may be
enhanced.
Metabolism
Ceftobiprole medocaril sodium is the pro-drug of the active moiety ceftobiprole. Conversion from the prodrug ceftobiprole medocaril sodium, to the active moiety ceftobiprole, occurs rapidly and is mediated by non-specific plasma esterases. Ceftobiprole undergoes minimal metabolism to the open-ring metabolite, which is microbiologically inactive
Ceftobiprole Medocaril Sodium Sterile Powder Preparation Products And Raw materials
Raw materials
Preparation Products
Ceftobiprole Medocaril Sodium Sterile Powder Suppliers
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- Fax
- 1-631-614-7828
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- Country
- United States
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- +17819995354
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- Country
- United States
- ProdList
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- Advantage
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