8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE

Product Name: 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
CAS No.: 99295-33-7
Chemical Name: 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
Synonyms: 159021;SKF 83566 hydrobromi;SKF 83566 HYDROBROMIDE;nicotine craving|||dorsal striatum|||Inhibitor;(+/-)-SKF-83566 HYDROCHLORIDE SELECTIVE DOPAMINE D1;8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol;1H-3-Benzazepin-7-ol, 8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-;7-bromo-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol hydrobromide;8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE;8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrochloride
CBNumber: CB7334038
Molecular Formula: C17H18BrNO
Formula Weight: 332.23
MOL File: 99295-33-7.mol

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8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Property

storage temp.: Desiccate at RT
solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: ≥14 mg/mL
form: solid
color: light tan

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1586
Product name: SKF83566hydrobromide
Purity: ≥98%(HPLC)
Packaging: 10
Price: $115
Updated: 2021/12/16

Tocris

Product number: 1586
Product name: SKF83566hydrobromide
Purity: ≥98%(HPLC)
Packaging: 50
Price: $482
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BRS0000210
Product name: SKF-83566
Purity: 95.00%
Packaging: 10MG
Price: $646.73
Updated: 2021/12/16

ChemScene

Product number: CS-0133715
Product name: SKF-83566
Purity: 99.86%
Packaging: 10mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-0133715
Product name: SKF-83566
Purity: 99.86%
Packaging: 5mg
Price: $95
Updated: 2021/12/16

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8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Chemical Properties,Usage,Production

Uses

SKF 83566 Hydrobromide is a very potent and selective D1-like dopamine receptor antagonist, specifically at the 5-HT2 receptor.

Definition

ChEBI: 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol is a benzazepine.

Biological Activity

Potent and selective D 1 -like dopamine receptor antagonist (K i ~ 0.56 nM for D 1 ; K B = 2 μ M for D 2 ). Also antagonist at the vascular 5-HT 2 receptor (K i = 11 nM). Centrally active following systemic administration in vivo .

8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Suppliers

China 33 Germany 2 Switzerland 1 United Kingdom 1 United States 6 Global 43

3B Pharmachem (Wuhan) International Co.,Ltd.

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EMMX Biotechnology LLC

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Career Henan Chemica Co

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Changzhou Chenhong Biotechnology Co., Ltd.

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Shanghai tingchong biology science and technology co., ltd

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Beijing Jin Ming Biotechnology Co., Ltd.

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Shanghai Universal Biotech Co.,Ltd

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Bide Pharmatech Ltd.

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99295-33-7, 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDERelated Search:

8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE

SKF 83566 HYDROBROMIDE

8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE

(+/-)-SKF-83566 HYDROCHLORIDE SELECTIVE DOPAMINE D1

(±)-SCH-24543, (±)-7-Bromo-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride

1H-3-Benzazepin-7-ol, 8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-

8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol

159021

SKF 83566 hydrobromi

8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrochloride

7-bromo-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol hydrobromide

nicotine craving|||dorsal striatum|||Inhibitor

99295-33-7

C17H18BrNOHCl

C17H18BrNOHBr

C17H19Br2NO

Dopamine receptor