ChemicalBook > CAS DataBase List > 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE

8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE

Product Name
8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
CAS No.
99295-33-7
Chemical Name
8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
Synonyms
159021;SKF 83566 hydrobromi;SKF 83566 HYDROBROMIDE;nicotine craving|||dorsal striatum|||Inhibitor;(+/-)-SKF-83566 HYDROCHLORIDE SELECTIVE DOPAMINE D1;8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol;1H-3-Benzazepin-7-ol, 8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-;7-bromo-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol hydrobromide;8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE;8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrochloride
CBNumber
CB7334038
Molecular Formula
C17H18BrNO
Formula Weight
332.23
MOL File
99295-33-7.mol
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8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Property

storage temp. 
Desiccate at RT
solubility 
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: ≥14 mg/mL
form 
solid
color 
light tan
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1586
Product name
SKF83566hydrobromide
Purity
≥98%(HPLC)
Packaging
10
Price
$115
Updated
2021/12/16
Tocris
Product number
1586
Product name
SKF83566hydrobromide
Purity
≥98%(HPLC)
Packaging
50
Price
$482
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BRS0000210
Product name
SKF-83566
Purity
95.00%
Packaging
10MG
Price
$646.73
Updated
2021/12/16
ChemScene
Product number
CS-0133715
Product name
SKF-83566
Purity
99.86%
Packaging
10mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-0133715
Product name
SKF-83566
Purity
99.86%
Packaging
5mg
Price
$95
Updated
2021/12/16
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8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Chemical Properties,Usage,Production

Uses

SKF 83566 Hydrobromide is a very potent and selective D1-like dopamine receptor antagonist, specifically at the 5-HT2 receptor.

Definition

ChEBI: 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol is a benzazepine.

Biological Activity

Potent and selective D 1 -like dopamine receptor antagonist (K i ~ 0.56 nM for D 1 ; K B = 2 μ M for D 2 ). Also antagonist at the vascular 5-HT 2 receptor (K i = 11 nM). Centrally active following systemic administration in vivo .

8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Suppliers

China 34 Germany 2 Switzerland 1 United Kingdom 1 United States 6 Global 44
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99295-33-7, 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDERelated Search:

8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE

  • SKF 83566 HYDROBROMIDE
  • 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
  • (+/-)-SKF-83566 HYDROCHLORIDE SELECTIVE DOPAMINE D1
  • (±)-SCH-24543, (±)-7-Bromo-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
  • 1H-3-Benzazepin-7-ol, 8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-
  • 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol
  • 159021
  • SKF 83566 hydrobromi
  • 8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrochloride
  • 7-bromo-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol hydrobromide
  • nicotine craving|||dorsal striatum|||Inhibitor
  • 99295-33-7
  • C17H18BrNOHCl
  • C17H18BrNOHBr
  • C17H19Br2NO
  • Dopamine receptor