ChemicalBook > CAS DataBase List > H2N-PEG6-CH2COOtBu

H2N-PEG6-CH2COOtBu

Product Name
H2N-PEG6-CH2COOtBu
CAS No.
297162-50-6
Chemical Name
H2N-PEG6-CH2COOtBu
Synonyms
NH2-PEG6-C1-Boc;H2N-PEG6-CH2COOtBu;NH2-PEG6-CH2COOtBu;NH2CH2CH2(OCH2CH2)5OCH2CO2-t-Bu;tert-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosanoate;3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester;NH-2-PEG6-C1-Boc,PROTAC Linkers,Inhibitor,NH2 PEG6 C1 Boc,inhibit,NH2PEG6C1Boc;tert-butyl 2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetate;H2N-PEG6-CH2COOtBu/3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester
CBNumber
CB73340573
Molecular Formula
C18H37NO8
Formula Weight
395.48828
MOL File
297162-50-6.mol
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H2N-PEG6-CH2COOtBu Property

Boiling point:
463.4±40.0 °C(Predicted)
Density 
1.065±0.06 g/cm3(Predicted)
pka
8.74±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS104025
Product name
H2N-PEG6-CH2COOtBu
Purity
95+%
Packaging
250mg
Price
$256
Updated
2021/12/16
Activate Scientific
Product number
AS104025
Product name
H2N-PEG6-CH2COOtBu
Purity
95+%
Packaging
1g
Price
$583
Updated
2021/12/16
Activate Scientific
Product number
AS104025
Product name
H2N-PEG6-CH2COOtBu
Purity
95+%
Packaging
5G
Price
$1478
Updated
2021/12/16
Acrotein
Product number
B-0891
Product name
H2N-PEG6-CH2COOtBu
Purity
97%
Packaging
0.5g
Price
$302.5
Updated
2021/12/16
purepeg
Product number
4328206
Product name
H2N-PEG6-CH2COOtBu
Purity
min.97%
Packaging
1g
Price
$450
Updated
2021/12/16
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H2N-PEG6-CH2COOtBu Chemical Properties,Usage,Production

Biological Activity

NH2-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

H2N-PEG6-CH2COOtBu Preparation Products And Raw materials

Raw materials

Preparation Products

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H2N-PEG6-CH2COOtBu Suppliers

PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Chengdu DingDang Pharmaceutical Co., Ltd.
Tel
028-86040038 13980902949;
Fax
028-85149890
Email
market@dingdangchem.com
Country
China
ProdList
1843
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28810
Advantage
58
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15394
Advantage
58
Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
Email
1927928688@qq.com
Country
China
ProdList
1388
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Wuhan Borenpharm Co., Ltd
Tel
027-65563561 18717150066
Fax
027-59218822
Email
3207347307@qq.com
Country
CHINA
ProdList
1238
Advantage
58
Shaanxi borno biotechnology co., LTD
Tel
+86-13759708231
Email
asherw9@hotmail.com
Country
China
ProdList
2350
Advantage
58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD
Tel
025-86755008 17751752005
Fax
025-86755228
Email
hszhang@bestfluorodrug.com
Country
China
ProdList
2358
Advantage
58

297162-50-6, H2N-PEG6-CH2COOtBuRelated Search:


  • H2N-PEG6-CH2COOtBu
  • NH2-PEG6-C1-Boc
  • NH2CH2CH2(OCH2CH2)5OCH2CO2-t-Bu
  • NH2-PEG6-CH2COOtBu
  • tert-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosanoate
  • NH-2-PEG6-C1-Boc,PROTAC Linkers,Inhibitor,NH2 PEG6 C1 Boc,inhibit,NH2PEG6C1Boc
  • H2N-PEG6-CH2COOtBu/3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester
  • 3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester
  • tert-butyl 2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetate
  • 297162-50-6