H2N-PEG6-CH2COOtBu

Product Name: H2N-PEG6-CH2COOtBu
CAS No.: 297162-50-6
Chemical Name: H2N-PEG6-CH2COOtBu
Synonyms: NH2-PEG6-C1-Boc;H2N-PEG6-CH2COOtBu;NH2-PEG6-CH2COOtBu;NH2CH2CH2(OCH2CH2)5OCH2CO2-t-Bu;tert-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosanoate;3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester;NH-2-PEG6-C1-Boc,PROTAC Linkers,Inhibitor,NH2 PEG6 C1 Boc,inhibit,NH2PEG6C1Boc;tert-butyl 2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetate;H2N-PEG6-CH2COOtBu/3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester
CBNumber: CB73340573
Molecular Formula: C18H37NO8
Formula Weight: 395.48828
MOL File: 297162-50-6.mol

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H2N-PEG6-CH2COOtBu Property

Boiling point:: 463.4±40.0 °C(Predicted)
Density: 1.065±0.06 g/cm3(Predicted)
storage temp.: Store at 0-8 °C
pka: 8.74±0.10(Predicted)
Appearance: colorless liquid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS104025
Product name: H2N-PEG6-CH2COOtBu
Purity: 95+%
Packaging: 250mg
Price: $256
Updated: 2021/12/16

Activate Scientific

Product number: AS104025
Product name: H2N-PEG6-CH2COOtBu
Purity: 95+%
Packaging: 1g
Price: $583
Updated: 2021/12/16

Activate Scientific

Product number: AS104025
Product name: H2N-PEG6-CH2COOtBu
Purity: 95+%
Packaging: 5G
Price: $1478
Updated: 2021/12/16

Acrotein

Product number: B-0891
Product name: H2N-PEG6-CH2COOtBu
Purity: 97%
Packaging: 0.5g
Price: $302.5
Updated: 2021/12/16

purepeg

Product number: 4328206
Product name: H2N-PEG6-CH2COOtBu
Purity: min.97%
Packaging: 1g
Price: $450
Updated: 2021/12/16

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H2N-PEG6-CH2COOtBu Chemical Properties,Usage,Production

Uses

NH2-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

NH2-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

H2N-PEG6-CH2COOtBu Preparation Products And Raw materials

Raw materials

Preparation Products

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H2N-PEG6-CH2COOtBu Suppliers

China 37 United States 2 Global 39

Chengdu DingDang Pharmaceutical Co., Ltd.

Tel: 028-86040038 13980902949;
Fax: 028-85149890
Email: market@dingdangchem.com
Country: China
ProdList: 1853
Advantage: 55

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9713
Advantage: 58

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1615
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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Wuhan Borenpharm Co., Ltd

Tel: 027-65563561 18717150066
Fax: 027-59218822
Email: 3207347307@qq.com
Country: CHINA
ProdList: 1238
Advantage: 58

Shaanxi borno biotechnology co., LTD

Tel: +86-13759708231
Email: asherw9@hotmail.com
Country: China
ProdList: 2373
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Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD

Tel: 025-86755008 17751752005
Fax: 025-86755228
Email: hszhang@bestfluorodrug.com
Country: China
ProdList: 2358
Advantage: 58

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View Lastest Price from H2N-PEG6-CH2COOtBu manufacturers

LAURENT

Product: NH2-PEG6-CH2COOtBu 297162-50-6
Price: US $412.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 300kg
Release date: 2025-11-18

297162-50-6, H2N-PEG6-CH2COOtBuRelated Search:

H2N-PEG6-CH2COOtBu

NH2-PEG6-C1-Boc

NH2CH2CH2(OCH2CH2)5OCH2CO2-t-Bu

NH2-PEG6-CH2COOtBu

tert-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosanoate

NH-2-PEG6-C1-Boc,PROTAC Linkers,Inhibitor,NH2 PEG6 C1 Boc,inhibit,NH2PEG6C1Boc

H2N-PEG6-CH2COOtBu/3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester

3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester

tert-butyl 2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetate

297162-50-6