3,4-Dimethoxyphenylboronic acid
- Product Name
- 3,4-Dimethoxyphenylboronic acid
- CAS No.
- 122775-35-3
- Chemical Name
- 3,4-Dimethoxyphenylboronic acid
- Synonyms
- AKOS BRN-0064;RARECHEM AH PB 0109;3,4-Dimethoxyphenylboronic;3,4-Dimethoxy boronic acid;4-DiMethoxyphenylboronic acid;3,4-DimethoxyphenylboronicAci;3,4-DIMETHOXYPHENYLBORONIC AICD;3,4-DIMETHOXYPHENYLBORONIC ACID;3,4-DIMETHOXYBENZENEBORONIC ACID;3,4-Dimethoxyphenylboronic acid,97%
- CBNumber
- CB7334366
- Molecular Formula
- C8H11BO4
- Formula Weight
- 181.98
- MOL File
- 122775-35-3.mol
3,4-Dimethoxyphenylboronic acid Property
- Melting point:
- 245-250 °C (lit.)
- Boiling point:
- 336.7±52.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Powder and Granules
- pka
- 8.48±0.10(Predicted)
- color
- White to light beige
- Water Solubility
- 25 g/L
- BRN
- 5334877
- InChI
- InChI=1S/C8H11BO4/c1-12-7-4-3-6(9(10)11)5-8(7)13-2/h3-5,10-11H,1-2H3
- InChIKey
- RCVDPBFUMYUKPB-UHFFFAOYSA-N
- SMILES
- B(C1=CC=C(OC)C(OC)=C1)(O)O
- CAS DataBase Reference
- 122775-35-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 37/39-26-36/37
- WGK Germany
- 3
- Hazard Note
- Irritant/Keep Cold
- HazardClass
- IRRITANT
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 480118
- Product name
- 3,4-Dimethoxyphenylboronic acid
- Purity
- ≥95.0%
- Packaging
- 5g
- Price
- $39.45
- Updated
- 2025/07/31
- Product number
- 480118
- Product name
- 3,4-Dimethoxyphenylboronic acid
- Purity
- ≥95.0%
- Packaging
- 25g
- Price
- $92.3
- Updated
- 2025/07/31
- Product number
- D3512
- Product name
- 3,4-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 5g
- Price
- $88
- Updated
- 2025/07/31
- Product number
- D3512
- Product name
- 3,4-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 25g
- Price
- $352
- Updated
- 2025/07/31
- Product number
- 273034
- Product name
- 3,4-Dimethoxyphenylboronic acid
- Packaging
- 25g
- Price
- $486
- Updated
- 2021/12/16
3,4-Dimethoxyphenylboronic acid Chemical Properties,Usage,Production
Chemical Properties
white to light beige powder and granules
Uses
suzuki reaction
Uses
3,4-Dimethoxyphenylboronic acid can be used:
- As a substrate in the cross-coupling reaction with 5,7-dichloropyrido[4,3-d]pyrimidine catalyzed by palladium.
- As a starting material for the synthesis of buflavine 1, a natural alkaloid.
- In one of the key synthetic steps for the preparation of lipidated malarial glycosylphosphatidylinositols (GPI) disaccharide.
- To prepare 3,3″,4,4″-tetramethoxy-1,1′:4′,1″-terphenyl by reacting with 1,4-dibromobenzene using Pd catalyst.
Synthesis
6315-89-5
122775-35-3
GENERAL PROCEDURE: 3,4-Dimethoxyaniline (0.5 mmol, 1.0 eq.) was dissolved in methanol (1.0 mL), hydrochloric acid (0.5 mL, 1.5 mmol, 3.0 eq.) was slowly added, followed by water (0.5 mL). The reaction mixture was stirred for 2 min, then sodium nitrite solution (0.25 mL, prepared by dissolving 35 mg NaNO2 in 0.25 mL of water) was added. The reaction mixture was stirred at 0-5 °C for 30 min, followed by the addition of methanol (1.0 mL) and hydrochloric acid (135 mg, 1.5 mmol, 3.0 equiv). Stirring was continued for 60 min. Upon completion of the reaction, it was diluted with water (10 mL) and extracted with dichloromethane (50 mL, 3 times). The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 3,4-dimethoxyphenylboronic acid.
References
[1] Synlett, 2014, vol. 25, # 11, p. 1577 - 1584
3,4-Dimethoxyphenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,4-Dimethoxyphenylboronic acid manufacturers
- Product
- 3,4-Dimethoxyphenylboronic acid 122775-35-3
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100mt/year
- Release date
- 2021-05-31
- Product
- 3,4-Dimethoxyphenylboronic acid 122775-35-3
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-11-20
- Product
- 3,4-Dimethoxyphenylboronic acid 122775-35-3
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-22