Hydroxy-PEG4-CH2CO2Me

Product Name: Hydroxy-PEG4-CH2CO2Me
CAS No.: 77303-64-1
Chemical Name: Hydroxy-PEG4-CH2CO2Me
Synonyms: HO-PEG4-CH2COOMe;Hydroxy-PEG4-CH2CO2Me;Hydroxy-PEG4-methyl acetate;Methyl 14-hydroxy-3,6,9,12-tetraoxatetradecan-1-oate;3,6,9,12-Tetraoxatetradecanoic acid, 14-hydroxy-, methyl ester;methyl 2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]acetate;HO-PEG4-CH2COOMe/3,6,9,12-Tetraoxatetradecanoic acid, 14-hydroxy-, methyl ester
CBNumber: CB73373634
Molecular Formula: C11H22O7
Formula Weight: 266.29
MOL File: 77303-64-1.mol

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Hydroxy-PEG4-CH2CO2Me Property

Boiling point:: 120 °C(Press: 0.001 Torr)
Density: 1.125±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Liquid
pka: 14.36±0.10(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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Hydroxy-PEG4-CH2CO2Me Chemical Properties,Usage,Production

Uses

Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Hydroxy-PEG4-CH2CO2Me Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxy-PEG4-CH2CO2Me Suppliers

China 22 United States 2 Global 24

Shanghai Yihe Biological Technology Co., Ltd.

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Amatek Scientific Co. Ltd.

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Changzhou Kechem Bio-Scientific Co., LTD.

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Shanghai Haohong Pharmaceutical Co., Ltd.

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Guangzhou Hongyuan Chemical Co.,Ltd

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Beijing Jin Ming Biotechnology Co., Ltd.

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Bide Pharmatech Ltd.

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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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TargetMol Chemicals Inc.

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Beijing Solarbio Science & Tecnology Co., Ltd.

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77303-64-1, Hydroxy-PEG4-CH2CO2MeRelated Search:

HO-PEG5-CH2COOtBu HS-PEG5-CH2CH2COOH Hydroxy-PEG1-methyl ester Hydroxy-PEG2-CH2CO2H HO-PEG6-CH2COOH HS-PEG4-CH2CH2COOH HO-PEG3-CH2COOH Hydroxy-PEG1-ethyl ester Hydroxy-PEG5-ethyl ester Hydroxy-PEG4-ethyl ester Hydroxy-PEG4-t-butyl ester 3,6,9,12,15-Pentaoxaheptadecanoic acid, 17-hydroxy-, methyl ester

Hydroxy-PEG4-CH2CO2Me

3,6,9,12-Tetraoxatetradecanoic acid, 14-hydroxy-, methyl ester

Hydroxy-PEG4-methyl acetate

HO-PEG4-CH2COOMe

HO-PEG4-CH2COOMe/3,6,9,12-Tetraoxatetradecanoic acid, 14-hydroxy-, methyl ester

methyl 2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]acetate

Methyl 14-hydroxy-3,6,9,12-tetraoxatetradecan-1-oate

77303-64-1