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Hydroxy-PEG4-t-butyl ester

Product Name
Hydroxy-PEG4-t-butyl ester
CAS No.
518044-32-1
Chemical Name
Hydroxy-PEG4-t-butyl ester
Synonyms
OH-PEG4-TBA;HO-PEG4-TBA;HO-PEG4-COOtBu;PEG5-t-butly ester;HO-PEG4-CH2CH2COOTBU;OH-PEG4-CH2CH2COOtBu;Hydroxy-PEG4-(CH2)2-Boc;HO-PEG4 tert-Butyl Ester;Hydroxy-PEG4-t-butly ester;tert-Butyl PEG4 propanoate
CBNumber
CB32747166
Molecular Formula
C15H30O7
Formula Weight
322.39
MOL File
518044-32-1.mol
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Hydroxy-PEG4-t-butyl ester Property

Boiling point:
406.8±35.0 °C(Predicted)
Density 
1.04746 g/mL
refractive index 
n/D 1.4492
storage temp. 
2-8°C
solubility 
Soluble in Water, DCM
pka
14.36±0.10(Predicted)
form 
liquid
color 
Colorless to Light yellow to Light orange
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Safety

HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
902586
Product name
Hydroxy-PEG4-t-butyl ester
Packaging
1g
Price
$274
Updated
2024/03/01
Sigma-Aldrich
Product number
902586
Product name
Hydroxy-PEG4-t-butyl ester
Packaging
250mg
Price
$74.6
Updated
2023/06/20
TCI Chemical
Product number
B5901
Product name
PEG5-Carboxylic Acid tert-Butyl Ester
Packaging
1G
Price
$111
Updated
2024/03/01
TCI Chemical
Product number
B5901
Product name
PEG5-Carboxylic Acid tert-Butyl Ester
Packaging
5G
Price
$376
Updated
2024/03/01
TRC
Product number
H936410
Product name
Hydroxy-Peg4-T-ButlyEster
Packaging
500mg
Price
$155
Updated
2021/12/16
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Hydroxy-PEG4-t-butyl ester Chemical Properties,Usage,Production

Description

Hydroxy-PEG4-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG4-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

Hydroxy-PEG4-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxy-PEG4-t-butyl ester Suppliers

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80514535 19917294565
Email
caoy@chemextension.com
Country
China
ProdList
2724
Advantage
58
Hebei led the biological technology co., LTD
Tel
18032827359
Email
2922659299@qq.com
Country
China
ProdList
58
Advantage
58
PharmaBlock Sciences (Nanjing),Inc.
Tel
400-0255188 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
6854
Advantage
65
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
+8618575662672 18575662672
Fax
021 51613951
Email
mzeng@3wpharm.com
Country
China
ProdList
9747
Advantage
57
Chengdu Pukang Biotechnology Co., Ltd
Tel
028-82550498 19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
479
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
021-50430803 18017383231
Fax
qq:2817624287
Email
983544897@qq.com
Country
China
ProdList
9352
Advantage
55
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View Lastest Price from Hydroxy-PEG4-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Hydroxy-PEG4-t-butyl ester 518044-32-1
Price
US $0.00/g
Min. Order
25g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-25
Career Henan Chemical Co
Product
Hydroxy-PEG-5-t-butyl ester 518044-32-1
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-20

518044-32-1, Hydroxy-PEG4-t-butyl esterRelated Search:


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