Hydroxy-PEG4-t-butyl ester
- Product Name
- Hydroxy-PEG4-t-butyl ester
- CAS No.
- 518044-32-1
- Chemical Name
- Hydroxy-PEG4-t-butyl ester
- Synonyms
- OH-PEG4-TBA;HO-PEG4-TBA;HO-PEG4-COOtBu;PEG5-t-butly ester;HO-PEG4-CH2CH2COOTBU;OH-PEG4-CH2CH2COOtBu;Hydroxy-PEG4-(CH2)2-Boc;HO-PEG4 tert-Butyl Ester;Hydroxy-PEG4-t-butly ester;tert-Butyl PEG4 propanoate
- CBNumber
- CB32747166
- Molecular Formula
- C15H30O7
- Formula Weight
- 322.39
- MOL File
- 518044-32-1.mol
Hydroxy-PEG4-t-butyl ester Property
- Boiling point:
- 406.8±35.0 °C(Predicted)
- Density
- 1.04746 g/mL
- refractive index
- n/D 1.4492
- storage temp.
- 2-8°C
- solubility
- Soluble in Water, DCM
- pka
- 14.36±0.10(Predicted)
- form
- liquid
- color
- Colorless to Light yellow to Light orange
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 902586
- Product name
- Hydroxy-PEG4-t-butyl ester
- Packaging
- 1g
- Price
- $274
- Updated
- 2024/03/01
- Product number
- 902586
- Product name
- Hydroxy-PEG4-t-butyl ester
- Packaging
- 250mg
- Price
- $74.6
- Updated
- 2023/06/20
- Product number
- B5901
- Product name
- PEG5-Carboxylic Acid tert-Butyl Ester
- Packaging
- 1G
- Price
- $111
- Updated
- 2024/03/01
- Product number
- B5901
- Product name
- PEG5-Carboxylic Acid tert-Butyl Ester
- Packaging
- 5G
- Price
- $376
- Updated
- 2024/03/01
- Product number
- H936410
- Product name
- Hydroxy-Peg4-T-ButlyEster
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
Hydroxy-PEG4-t-butyl ester Chemical Properties,Usage,Production
Description
Hydroxy-PEG4-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG4-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
Hydroxy-PEG4-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Hydroxy-PEG4-t-butyl ester Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28398
- Advantage
- 80
View Lastest Price from Hydroxy-PEG4-t-butyl ester manufacturers
- Product
- Hydroxy-PEG4-t-butyl ester 518044-32-1
- Price
- US $0.00/g
- Min. Order
- 25g
- Purity
- >98.00%
- Supply Ability
- 25g
- Release date
- 2024-03-25
- Product
- Hydroxy-PEG-5-t-butyl ester 518044-32-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-20