ChemicalBook > CAS DataBase List > Hydroxy-PEG4-t-butyl ester

Hydroxy-PEG4-t-butyl ester

Product Name
Hydroxy-PEG4-t-butyl ester
CAS No.
518044-32-1
Chemical Name
Hydroxy-PEG4-t-butyl ester
Synonyms
OH-PEG4-TBA;HO-PEG4-TBA;HO-PEG4-COOtBu;NH2-PEG4-COOtBu;HO-PEG4-C2COOtBu;PEG5-t-butly ester;HO-PEG4-CH2CH2COOTBU;OH-PEG4-CH2CH2COOtBu;Hydroxy-PEG4-(CH2)2-Boc;HO-PEG4 tert-Butyl Ester
CBNumber
CB32747166
Molecular Formula
C15H30O7
Formula Weight
322.39
MOL File
518044-32-1.mol
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Hydroxy-PEG4-t-butyl ester Property

Boiling point:
406.8±35.0 °C(Predicted)
Density 
1.04746 g/mL
refractive index 
n/D 1.4492
storage temp. 
2-8°C
solubility 
Soluble in Water, DCM
pka
14.36±0.10(Predicted)
form 
liquid
color 
Colorless to Light yellow to Light orange
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Safety

HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
902586
Product name
Hydroxy-PEG4-t-butyl ester
Packaging
1g
Price
$274
Updated
2024/03/01
Sigma-Aldrich
Product number
902586
Product name
Hydroxy-PEG4-t-butyl ester
Packaging
250mg
Price
$74.6
Updated
2023/06/20
TCI Chemical
Product number
B5901
Product name
PEG5-Carboxylic Acid tert-Butyl Ester
Packaging
1G
Price
$111
Updated
2024/03/01
TCI Chemical
Product number
B5901
Product name
PEG5-Carboxylic Acid tert-Butyl Ester
Packaging
5G
Price
$376
Updated
2024/03/01
TRC
Product number
H936410
Product name
Hydroxy-Peg4-T-ButlyEster
Packaging
500mg
Price
$155
Updated
2021/12/16
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Hydroxy-PEG4-t-butyl ester Chemical Properties,Usage,Production

Description

Hydroxy-PEG4-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG4-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

reaction suitability

reagent type: cross-linking reagent

Hydroxy-PEG4-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxy-PEG4-t-butyl ester Suppliers

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View Lastest Price from Hydroxy-PEG4-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Hydroxy-PEG4-t-butyl ester 518044-32-1
Price
US $0.00/g
Min. Order
25g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-25
Career Henan Chemical Co
Product
Hydroxy-PEG-5-t-butyl ester 518044-32-1
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-20

518044-32-1, Hydroxy-PEG4-t-butyl esterRelated Search:

Hydroxy-PEG4-CH2CO2Me Bis-PEG6-t-butyl ester tert-Butyl 3-[2-(2-{2-[2-(2-tert-butoxycarbonylethoxy)ethoxy]ethoxy}ethoxy) -ethoxy]propionate 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid PEG4-acid HO-PEG6-CH2CH2COOH α,ω-dipropionic acid tetraethylene glycol Bis-PEG6-acid alpha-[3-(1,1-Dimethylethoxy)-3-oxopropyl]-omega-hydroxypoly(oxy-1,2-ethanediyl) HO-PEG8-CH2CH2COOH Hydroxy-PEG5-acid PEG5-acid PEG7-t-butly ester PEG9-t-butly ester HO-PEG10-tBu Hydroxy-PEG3-t-butylester Hydroxy-PEG9-t-butyl ester TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-

  • HO-PEG4-CH2CH2COOTBU
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  • PEG5-t-butly ester
  • Hydroxy-PEG4-t-butly ester
  • OH-PEG4-CH2CH2COOtBu
  • OH-PEG4-TBA
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  • t-Butyl 3-Hydroxy(PEG4)propoinate
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  • tert-butyl 3-(2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)propanoate
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  • 4,7,10,13-Tetraoxapentadecanoic acid, 15-hydroxy-, 1,1-dimethylethyl ester
  • tert-Butyl PEG4 propanoate
  • PEG5-Carboxylic Acid tert-Butyl Ester
  • 1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oic Acid tert-Butyl Ester
  • HO-PEG4 tert-Butyl Ester
  • Hydroxy-dPEG4-t-butyl ester
  • HO-PEG4-CH2CH2COOtBu /4,7,10,13-Tetraoxapentadecanoic acid, 15-hydroxy-, 1,1-dimethylethyl ester
  • HO-PEG4-TBA
  • NH2-PEG4-COOtBu
  • HO-PEG4-C2COOtBu
  • 518044-32-1
  • peg