Z-ABU-OH
- Product Name
- Z-ABU-OH
- CAS No.
- 42918-86-5
- Chemical Name
- Z-ABU-OH
- Synonyms
- 02906;Z-D-Abu;Z-ABU-OH;Nsc164666;Z-L-Abu-OH;Z-2-ABU-OH;Cbz-Abu-OH;Z-D-Abu-OH;Z-ABU(2)-OH;Z-L-2Abu-OH
- CBNumber
- CB7343296
- Molecular Formula
- C12H15NO4
- Formula Weight
- 237.25
- MOL File
- 42918-86-5.mol
Z-ABU-OH Property
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Soluble in water or 1% acetic acid
- form
- Powder
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B194275
- Product name
- (S)-2-(((Benzyloxy)carbonyl)amino)butanoicAcid
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FA47262
- Product name
- Z-L-alpha-aminobutyric acid
- Packaging
- 2g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 02127
- Product name
- Z-L-α-aminobutyricacid,98%(HPLC)
- Purity
- 98%(HPLC)
- Packaging
- 25G
- Price
- $67.2
- Updated
- 2021/12/16
- Product number
- W6246
- Product name
- (S)-2-(Bezyloxycarbonylamino)butanoicacid
- Packaging
- 25g
- Price
- $89
- Updated
- 2021/12/16
- Product number
- AS40032
- Product name
- (S)-2-(Bezyloxycarbonylamino)butanoic acid
- Purity
- 97% ee
- Packaging
- 5G
- Price
- $45
- Updated
- 2021/12/16
Z-ABU-OH Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder
Uses
(S)-Cbz-2-aminobutyric Acid can be used as inhibitors in treatment of gastrointestinal and mental disorders.
Synthesis
1492-24-6
501-53-1
42918-86-5
To benzyl chloroformate (17.06 mL, 119 mmol) was added slowly and dropwise (S)-2-aminobutyric acid (11.2 g, 109 mmol) solution of tetrahydrofuran (THF, 200 mL) and 2M aqueous sodium carbonate (65.2 mL, 130 mmol) at 0 °C. After dropwise addition, the reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the aqueous layer was separated by extraction with H2O/tert-butyl methyl ether (TBME). The aqueous layer was acidified to pH=2 with 2M HCl aqueous solution and subsequently extracted with ethyl acetate (EtOAc). The organic layers were combined, dried with anhydrous sodium sulfate (Na2SO4), filtered and the filtrate was concentrated to afford (S)-2-(benzyloxycarbonylamino)butyric acid (22.8 g, 77% yield) as a colorless oil. The product could be used in the subsequent reaction without further purification.LC-MS analysis: [M-H]? 236.2; retention time (Rt) 0.76 min (LCMS method 1).
References
[1] Chemical and Pharmaceutical Bulletin, 1994, vol. 42, # 9, p. 1927 - 1930
[2] Patent: US2014/135330, 2014, A1. Location in patent: Paragraph 0230
[3] Journal of the American Chemical Society, 1964, vol. 86, p. 4991 - 4999
[4] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1964, p. 635 - 640
[5] Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1964, # 4, p. 685 - 692
Z-ABU-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Z-ABU-OH Suppliers
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- 4006356688 18621169109
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- 0086-571-85864795
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View Lastest Price from Z-ABU-OH manufacturers
- Product
- Z-ABU-OH 42918-86-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-12
- Product
- Z-ABU-OH 42918-86-5
- Price
- US $7.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24
- Product
- Z-ABU-OH 42918-86-5
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24