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Z-ABU-OH

Product Name
Z-ABU-OH
CAS No.
42918-86-5
Chemical Name
Z-ABU-OH
Synonyms
02906;Z-D-Abu;Z-ABU-OH;Nsc164666;Z-L-Abu-OH;Z-2-ABU-OH;Cbz-Abu-OH;Z-D-Abu-OH;Z-ABU(2)-OH;Z-L-2Abu-OH
CBNumber
CB7343296
Molecular Formula
C12H15NO4
Formula Weight
237.25
MOL File
42918-86-5.mol
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Z-ABU-OH Property

storage temp. 
Sealed in dry,2-8°C
solubility 
Soluble in water or 1% acetic acid
form 
Powder
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
B194275
Product name
(S)-2-(((Benzyloxy)carbonyl)amino)butanoicAcid
Packaging
50mg
Price
$60
Updated
2021/12/16
Chem-Impex
Product number
02127
Product name
Z-L-α-aminobutyricacid,98%(HPLC)
Purity
98%(HPLC)
Packaging
1G
Price
$11.2
Updated
2021/12/16
Chem-Impex
Product number
02127
Product name
Z-L-α-aminobutyric acid
Purity
≥ 98% (HPLC)
Packaging
5G
Price
$20
Updated
2021/12/16
Activate Scientific
Product number
AS40032
Product name
(S)-2-(Bezyloxycarbonylamino)butanoic acid
Purity
97% ee
Packaging
5G
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA47262
Product name
Z-L-alpha-aminobutyric acid
Packaging
2g
Price
$60
Updated
2021/12/16
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Z-ABU-OH Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

(S)-Cbz-2-aminobutyric Acid can be used as inhibitors in treatment of gastrointestinal and mental disorders.

Synthesis

1492-24-6

501-53-1

42918-86-5

To benzyl chloroformate (17.06 mL, 119 mmol) was added slowly and dropwise (S)-2-aminobutyric acid (11.2 g, 109 mmol) solution of tetrahydrofuran (THF, 200 mL) and 2M aqueous sodium carbonate (65.2 mL, 130 mmol) at 0 °C. After dropwise addition, the reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the aqueous layer was separated by extraction with H2O/tert-butyl methyl ether (TBME). The aqueous layer was acidified to pH=2 with 2M HCl aqueous solution and subsequently extracted with ethyl acetate (EtOAc). The organic layers were combined, dried with anhydrous sodium sulfate (Na2SO4), filtered and the filtrate was concentrated to afford (S)-2-(benzyloxycarbonylamino)butyric acid (22.8 g, 77% yield) as a colorless oil. The product could be used in the subsequent reaction without further purification.LC-MS analysis: [M-H]? 236.2; retention time (Rt) 0.76 min (LCMS method 1).

References

[1] Chemical and Pharmaceutical Bulletin, 1994, vol. 42, # 9, p. 1927 - 1930
[2] Patent: US2014/135330, 2014, A1. Location in patent: Paragraph 0230
[3] Journal of the American Chemical Society, 1964, vol. 86, p. 4991 - 4999
[4] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1964, p. 635 - 640
[5] Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1964, # 4, p. 685 - 692

Z-ABU-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-ABU-OH Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Nanjing Rate Biochemicals CO., LTD.
Tel
+86-(0)25-84931986,(0)18951962398
Fax
+86-(0)25-84931686
Country
China
ProdList
70
Advantage
62
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
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View Lastest Price from Z-ABU-OH manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Z-ABU-OH 42918-86-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-12
Career Henan Chemical Co
Product
Z-ABU-OH 42918-86-5
Price
US $7.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-24
Career Henan Chemical Co
Product
Z-ABU-OH 42918-86-5
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2018-12-24

42918-86-5, Z-ABU-OHRelated Search:


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