3,4-Dihydroxyphenylacetic acid

ChemicalBook > CAS DataBase List > 3,4-Dihydroxyphenylacetic acid

3,4-Dihydroxyphenylacetic acid

Product Name: 3,4-Dihydroxyphenylacetic acid
CAS No.: 102-32-9
Chemical Name: 3,4-Dihydroxyphenylacetic acid
Synonyms: 2-(3,4-dihydroxyphenyl)acetic acid;DOPAC;3,4-Dihydroxybenzeneacetic acid;3,4-DihydroxyphenyL;HOMOPROTOCATECHUIC ACID;Dihydroxyphenylacetic acid;N,N-DIMETHYL-P-PHENYLENEDIAMINE SULFATE;ba2773;Ba 2773;dopaceticacid
CBNumber: CB7358779
Molecular Formula: C8H8O4
Formula Weight: 168.15
MOL File: 102-32-9.mol

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3,4-Dihydroxyphenylacetic acid Property

Melting point:: 127-130 °C (lit.)
Boiling point:: 257.07°C (rough estimate)
Density: 1.3037 (rough estimate)
refractive index: 1.5090 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: water: soluble50mg/mL, clear, almost colorless
pka: 4.42±0.10(Predicted)
form: Powder, Crystals or Lumps
color: White to off-white
Water Solubility: Soluble in water and methanol.
BRN: 2211017
InChI: InChI=1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
InChIKey: CFFZDZCDUFSOFZ-UHFFFAOYSA-N
SMILES: C1(CC(O)=O)=CC=C(O)C(O)=C1
LogP: 0.980
CAS DataBase Reference: 102-32-9(CAS DataBase Reference)
NIST Chemistry Reference: Acetic acid, (3,4-dihydroxyphenyl)-,(102-32-9)
EPA Substance Registry System: 3,4-Dihydroxyphenylacetic acid (102-32-9)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: AH0590000
F: 10-23
HS Code: 29182900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 850217
Product name: 3,4-Dihydroxyphenylacetic acid
Purity: 98%
Packaging: 1g
Price: $46.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 11569
Product name: 3,4-Dihydroxyphenylacetic acid
Purity: analytical standard
Packaging: 25mg
Price: $71.4
Updated: 2024/03/01

TCI Chemical

Product number: D1283
Product name: 3,4-Dihydroxyphenylacetic Acid
Purity: >97.0%(T)
Packaging: 25g
Price: $241
Updated: 2024/03/01

Alfa Aesar

Product number: A15893
Product name: 3,4-Dihydroxyphenylacetic acid, 98+%
Packaging: 1g
Price: $23.65
Updated: 2024/03/01

Alfa Aesar

Product number: A15893
Product name: 3,4-Dihydroxyphenylacetic acid, 98+%
Packaging: 5g
Price: $85
Updated: 2024/03/01

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3,4-Dihydroxyphenylacetic acid Chemical Properties,Usage,Production

Description

3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA). Both degradations involve the enzymes monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), albeit in reverse order: MAO catalyzes dopamine to DOPAC, and COMT catalyzes DOPAC to HVA; whereas COMT catalyzes dopamine to 3-MT and MAO catalyzes 3-MT to HVA. The third metabolic end-product of dopamine is norepinephrine (noradrenaline).
DOPAC can be oxidized by hydrogen peroxide, leading to the formation of toxic metabolites which destroy dopamine storage vesicles in the substantia nigra. This may contribute to the failure of levodopa treatment of Parkinson's disease. A MAO-B inhibitor such as selegiline or rasagiline can prevent this from happening.
wikipedia

Chemical Properties

beige to light brown crystalline powder

Uses

3,4-Dihydroxyphenylacetic Acid is a metabolite of Dopamine (D533782).

Uses

3,4-Dihydroxyphenylacetic acid is an important metabolite when studying the behavior of the dopaminergic system.

Definition

ChEBI: (3,4-dihydroxyphenyl)acetic acid is a dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine. It has a role as a human metabolite. It is a dihydroxyphenylacetic acid and a member of catechols. It is functionally related to a phenylacetic acid. It is a conjugate acid of a (3,4-dihydroxyphenyl)acetate.

General Description

3,4-dihydroxyphenylacetic acid (DOPAC) is a normal constituent of rat brain tissue. A mass fragmentographic method for determination of DOPAC in rat brain tissue has been described. It is major metabolite of dopamine (DA). The voltammetric reduction of DOPAC has been studied at a glassy carbon electrode modified with single-wall carbon nanotubes (SWNTs). Semi-automatic fluorometric assay technique for DOPAC has been reported.

3,4-Dihydroxyphenylacetic acid Preparation Products And Raw materials

Raw materials

Hippuric acid Sodium acetate Acetic anhydride Hydrogen peroxide Benzene Veratraldehyde Hydrochloric acid Sodium hydroxide Magnesium sulfate Sodium carbonate

Preparation Products

Hydroxytyrosol 3,4-(METHYLENEDIOXY)PHENYLACETIC ACID

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View Lastest Price from 3,4-Dihydroxyphenylacetic acid manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: 3,4-Dihydroxyphenylacetic acid 102-32-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-11-14

Hebei Mojin Biotechnology Co., Ltd

Product: 3,4-Dihydroxyphenylacetic acid 102-32-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-11-16

Hebei Guanlang Biotechnology Co., Ltd.

Product: 3,4-Dihydroxyphenylacetic acid 102-32-9
Price: US $0.00-0.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2022-09-27

102-32-9, 3,4-Dihydroxyphenylacetic acidRelated Search:

DL-3,4-DIHYDROXYMANDELIC ACID DL-4-HYDROXY-3-METHOXYMANDELIC ACID 3,4,5-Trimethoxyphenylacetic acid 4,5-DIMETHOXY-2-NITROPHENYLACETIC ACID ETHYL 3,4-DIMETHOXYPHENYLACETATE METHYL HOMOVERATRATE 3-Hydroxy-4-methoxyphenylacetic acid 3,4-(METHYLENEDIOXY)PHENYLACETIC ACID 3,4-Diethoxyphenylacetic acid 3,5-DIMETHOXY-4-HYDROXYPHENYLACETIC ACID 2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID 2,3,4-TRIMETHOXYPHENYLACETIC ACID 3,4-Dihydroxyphenylacetic acid 1,3-BENZODIOXOLE-5-GLYCOLIC ACID Homovanillic acid DL-4-HYDROXY-3-METHOXYMANDELIC ACID ETHYL HOMOVANILLATE 4-Ethoxy-3-methoxyphenylacetic acid

Ba 2773

DIHYDROXYPHENYLACETIC ACID, 3,4-(RG)

Dopac/(3,4-dihydroxyphenyl)-aceticaci

Hypoxanthine DisodiuM

(3,4-dihydroxyphenyl)-aceticaci

3,4-Dihydroxybenzeneacetic acid

3,4-dihydroxy-benzeneaceticaci

3,4-dihydroxybenzeneaceticacid

3,4-Dihydroxyphenylacetic acid, 98+%

3,4-Dihydroxyphenylcaetic acid

2-(3,4-dihydroxyphenyl)acetic acid

3,4-DIHYDROXYPHENYLACETIC ACID, 97+%

DOPAC, Homoprotocatechuic acid

ba2773

Benzeneacetic acid, 3,4-dihydroxy-

Dihydroxyphenylacetic acid

dihydroxyphenylaceticacid

Dopacetic acid

dopaceticacid

PYROCATECHOL-4-ACETIC ACID

N,N-DIMETHYL-P-PHENYLENEDIAMINE SULFATE

CATECHOL-4-ACETIC ACID

DOPAC

HOMOPROTOCATECHUIC ACID

4-CARBOXYMETHYLPYROCATECHOL

4-CARBOXYMETHYLCATECHOL

3,4-DIHYDROXYPHENYLACETIC ACID

Catechol-p-acetic acid

4-Carboxymethylcatechol 4-Carboxymethylpyrocatechol Catechol-4-acetic Acid Homoprotocatechuic Acid Pyrocatechol-4-acetic Acid

3,4-DihydroxyphenyL

3,4-Dihydroxyphenylacetic Acid &gt

Mouse 3,4 dihydroxyphenylacetic acid elisa kit

CAS 102-32-9 3, 4-Dihydroxybenzeneacetic Acid

Senecionine Impurity 1

102-32-9

HO2C6H3CH2CO2H

HOHOC6H3CH2COOH

HO2C6H3CD2COOH

Carbonyl Compounds

Carboxylic Acids

Building Blocks

Organic Building Blocks

buildingblock

Aromatic Phenylacetic Acids and Derivatives