3,4-Dihydroxyphenylacetic acid

ChemicalBook > CAS DataBase List > 3,4-Dihydroxyphenylacetic acid

3,4-Dihydroxyphenylacetic acid

Product Name: 3,4-Dihydroxyphenylacetic acid
CAS No.: 102-32-9
Chemical Name: 3,4-Dihydroxyphenylacetic acid
Synonyms: 2-(3,4-dihydroxyphenyl)acetic acid;DOPAC;3,4-Dihydroxybenzeneacetic acid;3,4-DihydroxyphenyL;HOMOPROTOCATECHUIC ACID;Dihydroxyphenylacetic acid;N,N-DIMETHYL-P-PHENYLENEDIAMINE SULFATE;ba2773;Ba 2773;dopaceticacid
CBNumber: CB7358779
Molecular Formula: C8H8O4
Formula Weight: 168.15
MOL File: 102-32-9.mol

Less

3,4-Dihydroxyphenylacetic acid Property

Melting point:: 127-130 °C (lit.)
Boiling point:: 257.07°C (rough estimate)
Density: 1.3037 (rough estimate)
refractive index: 1.5090 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: water: soluble50mg/mL, clear, almost colorless
pka: 4.42±0.10(Predicted)
form: Powder, Crystals or Lumps
color: White to off-white
Water Solubility: Soluble in water and methanol.
BRN: 2211017
InChI: InChI=1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
InChIKey: CFFZDZCDUFSOFZ-UHFFFAOYSA-N
SMILES: C1(CC(O)=O)=CC=C(O)C(O)=C1
LogP: 0.980
CAS DataBase Reference: 102-32-9(CAS DataBase Reference)
NIST Chemistry Reference: Acetic acid, (3,4-dihydroxyphenyl)-,(102-32-9)
EPA Substance Registry System: 3,4-Dihydroxyphenylacetic acid (102-32-9)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: AH0590000
F: 10-23
HS Code: 29182900

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 850217
Product name: 3,4-Dihydroxyphenylacetic acid
Purity: 98%
Packaging: 1g
Price: $46.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 11569
Product name: 3,4-Dihydroxyphenylacetic acid
Purity: analytical standard
Packaging: 25mg
Price: $71.4
Updated: 2024/03/01

TCI Chemical

Product number: D1283
Product name: 3,4-Dihydroxyphenylacetic Acid
Purity: >97.0%(T)
Packaging: 25g
Price: $241
Updated: 2024/03/01

Alfa Aesar

Product number: A15893
Product name: 3,4-Dihydroxyphenylacetic acid, 98+%
Packaging: 1g
Price: $23.65
Updated: 2024/03/01

Alfa Aesar

Product number: A15893
Product name: 3,4-Dihydroxyphenylacetic acid, 98+%
Packaging: 5g
Price: $85
Updated: 2024/03/01

Less

3,4-Dihydroxyphenylacetic acid Chemical Properties,Usage,Production

Description

3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA). Both degradations involve the enzymes monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), albeit in reverse order: MAO catalyzes dopamine to DOPAC, and COMT catalyzes DOPAC to HVA; whereas COMT catalyzes dopamine to 3-MT and MAO catalyzes 3-MT to HVA. The third metabolic end-product of dopamine is norepinephrine (noradrenaline).
DOPAC can be oxidized by hydrogen peroxide, leading to the formation of toxic metabolites which destroy dopamine storage vesicles in the substantia nigra. This may contribute to the failure of levodopa treatment of Parkinson's disease. A MAO-B inhibitor such as selegiline or rasagiline can prevent this from happening.
wikipedia

Chemical Properties

beige to light brown crystalline powder

Uses

3,4-Dihydroxyphenylacetic Acid is a metabolite of Dopamine (D533782).

Uses

3,4-Dihydroxyphenylacetic acid is an important metabolite when studying the behavior of the dopaminergic system.

Definition

ChEBI: (3,4-dihydroxyphenyl)acetic acid is a dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine. It has a role as a human metabolite. It is a dihydroxyphenylacetic acid and a member of catechols. It is functionally related to a phenylacetic acid. It is a conjugate acid of a (3,4-dihydroxyphenyl)acetate.

General Description

3,4-dihydroxyphenylacetic acid (DOPAC) is a normal constituent of rat brain tissue. A mass fragmentographic method for determination of DOPAC in rat brain tissue has been described. It is major metabolite of dopamine (DA). The voltammetric reduction of DOPAC has been studied at a glassy carbon electrode modified with single-wall carbon nanotubes (SWNTs). Semi-automatic fluorometric assay technique for DOPAC has been reported.

3,4-Dihydroxyphenylacetic acid Preparation Products And Raw materials

Raw materials

Hippuric acid Sodium acetate Acetic anhydride Hydrogen peroxide Benzene Veratraldehyde Hydrochloric acid Sodium hydroxide Magnesium sulfate Sodium carbonate

Preparation Products

Hydroxytyrosol 3,4-(METHYLENEDIOXY)PHENYLACETIC ACID

Less

3,4-Dihydroxyphenylacetic acid Suppliers

Americas 1 Belgium 1 Canada 1 China 239 Europe 3 France 1 Germany 3 India 12 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 United Kingdom 10 United States 34 Global 312

NINGBO SYNTAME BIOTECH CO LTD

Tel: +86-0574-28802872 +86-18668283131
Email: sales@syntame.com
Country: China
ProdList: 105
Advantage: 58

Jiangxi Zhiyan Biopharmaceutical Technology Co., Ltd

Tel: 13732973797
Email: liu@zybiopharma.com
Country: China
ProdList: 270
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
Advantage: 61

Jinxiang Chemical (Danyang) Products Co., Ltd.

Tel: 025-86819862 13913839793
Fax: 0086-25-86819859
Email: nancyzong@jinchemical.com
Country: China
ProdList: 97
Advantage: 74

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11655
Advantage: 64

Wuhan Wei Shunda Technology Development Co., Ltd.

Tel: 86-027-88774375
Fax: 86-027-88416321
Email: mwmwhot@163.com
Country: China
ProdList: 233
Advantage: 65

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8837
Advantage: 52

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18738
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11707
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2866
Advantage: 58

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4940
Advantage: 60

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 18017383231 18017383231
Fax: qq：2817624287
Email: lyh_antaeus@163.com
Country: China
ProdList: 9347
Advantage: 55

China Kouting Group Limited

Tel: +86 (21) 5811-6473 5811-6475
Fax: +86 (21) 6129-4103
Email: sales@koutingchina.com
Country: China
ProdList: 496
Advantage: 60

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9545
Advantage: 55

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8065
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9894
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Country: China
ProdList: 2930
Advantage: 58

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9346
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7887
Advantage: 56

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5874
Advantage: 58

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10274
Advantage: 55

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-+86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 11578
Advantage: 59

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 18112977050
Email: cb6@aikonchem.com
Country: China
ProdList: 16684
Advantage: 50

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Giant chemicals

Tel: 028-85434334 18108076537
Fax: QQ：245797092
Email: market@gianthx.com
Country: China
ProdList: 4505
Advantage: 56

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 7057
Advantage: 55

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

Less

View Lastest Price from 3,4-Dihydroxyphenylacetic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 3,4-Dihydroxyphenylacetic acid 102-32-9
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-12

Hebei Yanxi Chemical Co., Ltd.

Product: 3,4-Dihydroxyphenylacetic acid 102-32-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-11-14

Hebei Weibang Biotechnology Co., Ltd

Product: 3,4-Dihydroxyphenylacetic acid 102-32-9
Price: US $0.00-0.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-25

102-32-9, 3,4-Dihydroxyphenylacetic acidRelated Search:

DL-3,4-DIHYDROXYMANDELIC ACID DL-4-HYDROXY-3-METHOXYMANDELIC ACID 3,4,5-Trimethoxyphenylacetic acid 4,5-DIMETHOXY-2-NITROPHENYLACETIC ACID ETHYL 3,4-DIMETHOXYPHENYLACETATE METHYL HOMOVERATRATE 3-Hydroxy-4-methoxyphenylacetic acid 3,4-(METHYLENEDIOXY)PHENYLACETIC ACID 3,4-Diethoxyphenylacetic acid 3,5-DIMETHOXY-4-HYDROXYPHENYLACETIC ACID 2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID 2,3,4-TRIMETHOXYPHENYLACETIC ACID 3,4-Dihydroxyphenylacetic acid 1,3-BENZODIOXOLE-5-GLYCOLIC ACID Homovanillic acid DL-4-HYDROXY-3-METHOXYMANDELIC ACID ETHYL HOMOVANILLATE 4-Ethoxy-3-methoxyphenylacetic acid

Ba 2773

DIHYDROXYPHENYLACETIC ACID, 3,4-(RG)

Dopac/(3,4-dihydroxyphenyl)-aceticaci

Hypoxanthine DisodiuM

(3,4-dihydroxyphenyl)-aceticaci

3,4-Dihydroxybenzeneacetic acid

3,4-dihydroxy-benzeneaceticaci

3,4-dihydroxybenzeneaceticacid

3,4-Dihydroxyphenylacetic acid, 98+%

3,4-Dihydroxyphenylcaetic acid

2-(3,4-dihydroxyphenyl)acetic acid

3,4-DIHYDROXYPHENYLACETIC ACID, 97+%

DOPAC, Homoprotocatechuic acid

ba2773

Benzeneacetic acid, 3,4-dihydroxy-

Dihydroxyphenylacetic acid

dihydroxyphenylaceticacid

Dopacetic acid

dopaceticacid

PYROCATECHOL-4-ACETIC ACID

N,N-DIMETHYL-P-PHENYLENEDIAMINE SULFATE

CATECHOL-4-ACETIC ACID

DOPAC

HOMOPROTOCATECHUIC ACID

4-CARBOXYMETHYLPYROCATECHOL

4-CARBOXYMETHYLCATECHOL

3,4-DIHYDROXYPHENYLACETIC ACID

Catechol-p-acetic acid

4-Carboxymethylcatechol 4-Carboxymethylpyrocatechol Catechol-4-acetic Acid Homoprotocatechuic Acid Pyrocatechol-4-acetic Acid

3,4-DihydroxyphenyL

3,4-Dihydroxyphenylacetic Acid &gt

Mouse 3,4 dihydroxyphenylacetic acid elisa kit

CAS 102-32-9 3, 4-Dihydroxybenzeneacetic Acid

Senecionine Impurity 1

Drotaveraldine Impurity 08

3,4-Dihydroxyphenylacetic acid in methanol

102-32-9

HO2C6H3CH2CO2H

HOHOC6H3CH2COOH

HO2C6H3CD2COOH

Carbonyl Compounds

Carboxylic Acids

Building Blocks

Organic Building Blocks

buildingblock

Aromatic Phenylacetic Acids and Derivatives