3,4-Dihydroxyphenylacetic acid
- Product Name
- 3,4-Dihydroxyphenylacetic acid
- CAS No.
- 102-32-9
- Chemical Name
- 3,4-Dihydroxyphenylacetic acid
- Synonyms
- 2-(3,4-dihydroxyphenyl)acetic acid;DOPAC;3,4-Dihydroxybenzeneacetic acid;3,4-DihydroxyphenyL;HOMOPROTOCATECHUIC ACID;Dihydroxyphenylacetic acid;N,N-DIMETHYL-P-PHENYLENEDIAMINE SULFATE;ba2773;Ba 2773;dopaceticacid
- CBNumber
- CB7358779
- Molecular Formula
- C8H8O4
- Formula Weight
- 168.15
- MOL File
- 102-32-9.mol
3,4-Dihydroxyphenylacetic acid Property
- Melting point:
- 127-130 °C (lit.)
- Boiling point:
- 257.07°C (rough estimate)
- Density
- 1.3037 (rough estimate)
- refractive index
- 1.5090 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- water: soluble50mg/mL, clear, almost colorless
- pka
- 4.42±0.10(Predicted)
- form
- Powder, Crystals or Lumps
- color
- White to off-white
- Water Solubility
- Soluble in water and methanol.
- BRN
- 2211017
- InChI
- InChI=1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
- InChIKey
- CFFZDZCDUFSOFZ-UHFFFAOYSA-N
- SMILES
- C1(CC(O)=O)=CC=C(O)C(O)=C1
- LogP
- 0.980
- CAS DataBase Reference
- 102-32-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Acetic acid, (3,4-dihydroxyphenyl)-,(102-32-9)
- EPA Substance Registry System
- 3,4-Dihydroxyphenylacetic acid (102-32-9)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 850217
- Product name
- 3,4-Dihydroxyphenylacetic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $46.1
- Updated
- 2024/03/01
- Product number
- 11569
- Product name
- 3,4-Dihydroxyphenylacetic acid
- Purity
- analytical standard
- Packaging
- 25mg
- Price
- $71.4
- Updated
- 2024/03/01
- Product number
- D1283
- Product name
- 3,4-Dihydroxyphenylacetic Acid
- Purity
- >97.0%(T)
- Packaging
- 25g
- Price
- $241
- Updated
- 2024/03/01
- Product number
- A15893
- Product name
- 3,4-Dihydroxyphenylacetic acid, 98+%
- Packaging
- 1g
- Price
- $23.65
- Updated
- 2024/03/01
- Product number
- A15893
- Product name
- 3,4-Dihydroxyphenylacetic acid, 98+%
- Packaging
- 5g
- Price
- $85
- Updated
- 2024/03/01
3,4-Dihydroxyphenylacetic acid Chemical Properties,Usage,Production
Description
3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA). Both degradations involve the enzymes monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), albeit in reverse order: MAO catalyzes dopamine to DOPAC, and COMT catalyzes DOPAC to HVA; whereas COMT catalyzes dopamine to 3-MT and MAO catalyzes 3-MT to HVA. The third metabolic end-product of dopamine is norepinephrine (noradrenaline).
DOPAC can be oxidized by hydrogen peroxide, leading to the formation of toxic metabolites which destroy dopamine storage vesicles in the substantia nigra. This may contribute to the failure of levodopa treatment of Parkinson's disease. A MAO-B inhibitor such as selegiline or rasagiline can prevent this from happening.
wikipedia
Chemical Properties
beige to light brown crystalline powder
Uses
3,4-Dihydroxyphenylacetic Acid is a metabolite of Dopamine (D533782).
Uses
3,4-Dihydroxyphenylacetic acid is an important metabolite when studying the behavior of the dopaminergic system.
Definition
ChEBI: (3,4-dihydroxyphenyl)acetic acid is a dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine. It has a role as a human metabolite. It is a dihydroxyphenylacetic acid and a member of catechols. It is functionally related to a phenylacetic acid. It is a conjugate acid of a (3,4-dihydroxyphenyl)acetate.
General Description
3,4-dihydroxyphenylacetic acid (DOPAC) is a normal constituent of rat brain tissue. A mass fragmentographic method for determination of DOPAC in rat brain tissue has been described. It is major metabolite of dopamine (DA). The voltammetric reduction of DOPAC has been studied at a glassy carbon electrode modified with single-wall carbon nanotubes (SWNTs). Semi-automatic fluorometric assay technique for DOPAC has been reported.
3,4-Dihydroxyphenylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,4-Dihydroxyphenylacetic acid manufacturers
- Product
- 3,4-Dihydroxyphenylacetic acid 102-32-9
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-12-12
- Product
- 3,4-Dihydroxyphenylacetic acid 102-32-9
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-11-14
- Product
- 3,4-Dihydroxyphenylacetic acid 102-32-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-25