5-BROMO-2-FLUOROCINNAMIC ACID
- Product Name
- 5-BROMO-2-FLUOROCINNAMIC ACID
- CAS No.
- 202865-71-2
- Chemical Name
- 5-BROMO-2-FLUOROCINNAMIC ACID
- Synonyms
- TIMTEC-BB SBB006748;RARECHEM BK HW 0189;5-Bromo-2-fluorociamic acid;5-BROMO-2-FLUOROCINNAMIC ACID;5-Bromo-2-fluorocinnamicacid98%;5-Bromo-2-fluorocinnamic acid 98%;5-BROMO-2-FLUOROCINNAMIC ACID USP/EP/BP;3-(5-BROMO-2-FLUORO-PHENYL)-ACRYLIC ACID;(E)-3-(5-broMo-2-fluorophenyl)acrylic acid;3-(5-BROMO-2-FLUOROPHENYL)-2-PROPENOIC ACID
- CBNumber
- CB7359736
- Molecular Formula
- C9H6BrFO2
- Formula Weight
- 245.05
- MOL File
- 202865-71-2.mol
5-BROMO-2-FLUOROCINNAMIC ACID Property
- Melting point:
- 195-199 °C
- Boiling point:
- 336.0±32.0 °C(Predicted)
- Density
- 1.6228 (rough estimate)
- refractive index
- 1.4240 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.14±0.10(Predicted)
- Appearance
- White to off-white Solid
- CAS DataBase Reference
- 202865-71-2(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B692208
- Product name
- 5-Bromo-2-fluorocinnamic acid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- CS-0044968
- Product name
- 5-Bromo-2-fluorocinnamic acid
- Purity
- >97.0%
- Packaging
- 25g
- Price
- $98
- Updated
- 2021/12/16
- Product number
- V4184
- Product name
- 5-Bromo-2-fluorocinnamic acid
- Packaging
- 5g
- Price
- $128
- Updated
- 2021/12/16
- Product number
- 2921-B-02
- Product name
- 5-Bromo-2-fluorocinnamic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $135
- Updated
- 2021/12/16
- Product number
- 2921-B-02
- Product name
- 5-Bromo-2-fluorocinnamic acid
- Purity
- 98%
- Packaging
- 5G
- Price
- $45
- Updated
- 2021/12/16
5-BROMO-2-FLUOROCINNAMIC ACID Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Synthesis
141-82-2
93777-26-5
202865-71-2
A Knoevenagel condensation reaction catalyzed by piperidine (0.5 mL, 4.9 mmol) in pyridine (11.4 mL) was carried out with 5-bromo-2-fluorobenzaldehyde (5.0 g, 24.6 mmol) and malonic acid (5.6 g, 53.7 mmol). The reaction mixture was stirred at 100 °C for 3 h. After completion of the reaction, the solvent was removed by concentration under reduced pressure. Distilled water was added to the concentrated mixture and the precipitate was collected by filtration. The resulting crude product was purified by recrystallization with ethanol to give the final 5-bromo-2-fluorocinnamic acid (1.3 g, white solid). The structure of the product was confirmed by 1H NMR (400 MHz, CD3OD): δ 7.89 (d, 1H), 7.74-7.70 (m, 2H), 7.15 (t, 1H), 6.62 (d, 1H).
References
[1] Patent: US2015/291563, 2015, A1. Location in patent: Paragraph 0163; 0164
5-BROMO-2-FLUOROCINNAMIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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