7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE
- Product Name
- 7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE
- CAS No.
- 6742-12-7
- Chemical Name
- 7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE
- Synonyms
- formycin;NSC 102811;formycin A;FORMYCIN MONOHYDRATE;FORMYCIN A MONOHYDRATE;8-Aza-9-deazaadenosine;8-AZA-9-DEAZAADENOSINE MONOHYDRATE;3-β-D-Ribofuranosyl-1H-pyrazolo[4,3-d]pyrimidine-7-amine;3-(β-D-Ribofuranosyl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine;3-d)pyrimidine,7-amino-3-beta-d-ribofuranosyl-1h-pyrazolo(
- CBNumber
- CB7395563
- Molecular Formula
- C10H13N5O4
- Formula Weight
- 267.25
- MOL File
- 6742-12-7.mol
7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE Property
- Melting point:
- 141-144 °C (decomp)
- Boiling point:
- 709.5±60.0 °C(Predicted)
- Density
- 1.771±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO: soluble1mg/mL
- form
- powder
- pka
- 8.37±0.50(Predicted)
- color
- white to off-white
- BRN
- 624229
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SMB00287
- Product name
- Formycin A
- Purity
- from
- Packaging
- 10mg
- Price
- $416.78
- Updated
- 2025/07/31
- Product number
- API0010090
- Product name
- FORMYCIN A
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $407.4
- Updated
- 2021/12/16
7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE Chemical Properties,Usage,Production
Description
Formycin (Formycin A) is isolated from Nocardia interforma and from Streptomyces lavendulae , . The antibiotic is effective against Xanthomonas oryzae and Pellicularia filamentosa. Its activity against Yoshida rat sarcoma cell is enhanced by coformycin. Formycin B inhibits Xanthomonas oryzae and interferes with multiplication of influenza A virus in the cells of chick chorioallantoic membrane . Oxoformycin B shows no activity against Xanthomonas oryzae .
Uses
Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM. Formycin A shows antitumor and antiviral activities[1][2].
Definition
ChEBI: Formycin A is a formycin. It has a role as an antineoplastic agent.
IC 50
HIV-1: 10 μM (EC50)
References
[1] Dapp MJ , et al. Discovery of novel ribonucleoside analogs with activity against human immunodeficiency virus type 1.J Virol. 2014 Jan;88(1):354-63. DOI:10.1128/JVI.02444-13
[2] Zhang M, et al. Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds. Appl Environ Microbiol. 2020 Jan 7;86(2). DOI:10.1128/AEM.01971-19
7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE Preparation Products And Raw materials
Raw materials
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