(1H-PYRAZOL-3-YL)METHANOL
- Product Name
- (1H-PYRAZOL-3-YL)METHANOL
- CAS No.
- 23585-49-1
- Chemical Name
- (1H-PYRAZOL-3-YL)METHANOL
- Synonyms
- 3-(HYDROXYMETHYL)PYRAZOLE;1H-PYRAZOLE-3-METHANOL;1H-pyarzole-3-methanol;(1H-PYRAZOL-3-YL)METHANOL;3-HyroxyMethyl-1H-pyrazole;1H-Pyrazole-3-methanol 95%;3-HyroxyMethyl-1H-pyrazol...;1H-Pyrazole-3-methanol (9CI, ACI);3-(Hydroxymethyl)pyrazole , (1H-Pyrazol-3-yl)methanol
- CBNumber
- CB2315276
- Molecular Formula
- C4H6N2O
- Formula Weight
- 98.1
- MOL File
- 23585-49-1.mol
(1H-PYRAZOL-3-YL)METHANOL Property
- Melting point:
- 184-185 °C
- Boiling point:
- 137-140 °C(Press: 0.5 Torr)
- Density
- 1.225 g/cm3(Temp: 25 °C)
- storage temp.
- 2-8°C
- form
- solid
- pka
- 13.59±0.10(Predicted)
- color
- Off White
Safety
- HS Code
- 2933119000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- H953548
- Product name
- (1H-Pyrazol-3-yl)methanol
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR52395
- Product name
- (1H-Pyrazol-3-yl)methanol
- Packaging
- 1g
- Price
- $218
- Updated
- 2021/12/16
- Product number
- 1603AB
- Product name
- (1H-Pyrazol-3-yl)methanol
- Packaging
- 250mg
- Price
- $134
- Updated
- 2021/12/16
- Product number
- 4H56-1-LX
- Product name
- 3-Hyroxymethyl-1H-pyrazole
- Packaging
- 1g
- Price
- $144
- Updated
- 2021/12/16
- Product number
- 112426
- Product name
- 3-Hyroxymethyl-1H-pyrazole
- Packaging
- 1g
- Price
- $186
- Updated
- 2021/12/16
(1H-PYRAZOL-3-YL)METHANOL Chemical Properties,Usage,Production
Chemical Properties
Colorless Liquid
Synthesis
1621-91-6
23585-49-1
General procedure for the synthesis of 3-(hydroxymethyl)pyrazole from 1H-pyrazole-3-carboxylic acid: a tetrahydrofuran solution (20 mL) of aluminum (III) hydride was cooled to 0 °C under nitrogen protection and stirred. To this solution was added 1H-pyrazole-3-carboxylic acid (4 g, 35.7 mmol). The reaction mixture was stirred at room temperature for 1 hour and then heated to reflux overnight. Upon completion of the reaction, the mixture was cooled to 0 °C and water (2.7 mL), 10% NaOH solution (5.4 mL) and water (8.1 mL) were added sequentially to quench the reaction. After quenching, the mixture was continued to be stirred at 0 °C for 30 min and then filtered through a Celite pad. The filtrate was concentrated under reduced pressure to remove the solvent and the resulting residue was purified by silica gel column chromatography (eluent: ethyl acetate/hexane, 1/2, v/v) to afford the target product (1H-pyrazol-3-yl)methanol (1.9 g, 19.37 mmol, 54% yield) as a buttery solid. m/z = 81.1 [M + H - H2O]+ was shown by LCMS detection.
References
[1] Patent: WO2017/216726, 2017, A1. Location in patent: Page/Page column 968
[2] Patent: WO2014/66795, 2014, A1. Location in patent: Paragraph 0175
(1H-PYRAZOL-3-YL)METHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (1H-PYRAZOL-3-YL)METHANOL manufacturers
- Product
- (1H-PYRAZOL-3-YL)METHANOL 23585-49-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 1H-pyrazol-5-ylmethanol 23585-49-1
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg,10kg,100kg
- Release date
- 2020-01-09